«Shorter stature appears to lead to higher mortality rates, longer waiting times
for lung transplantation.»
Although there is anecdotal evidence that suggests shorter adults wait longer
for lung transplantation, this is the first study to the researchers» knowledge of an analysis that focuses on the impact of short stature on waiting time and waiting list mortality.
Shorter adults are also more likely to be placed on mechanical ventilation while they wait
for lung transplantation, said lead author Jessica Sell, MPH, of the Columbia University Medical Center in New York.
What they found is that deaths in the 90 days after an operation
for lung transplantation have gone down over the past 25 years from 19.4 % to 10 %.
Not exact matches
More than 2,000 U.S. children are on an organ transplant waiting list
for kidneys, livers, hearts,
lungs and other organs, according to the federal Organ Procurement and
Transplantation Network.
Caucasian and Hispanic children who undergo
lung transplantation appear to be at greater risk
for developing chronic kidney disease, or CKD, according to a small retrospective study conducted at Texas Children's Hospital.
But patients with the antibodies in their blood are at high risk of dying while waiting
for a perfect match, said Brian Feingold, M.D., M.S., study lead author and medical director of Pediatric Heart and Heart -
Lung Transplantation at Children's Hospital of Pittsburgh of UPMC and associate professor of the University of Pittsburgh School of Medicine in Pennsylvania.
To continue to improve long - term results after
lung transplantation, the authors suggest that better collaboration is needed between the
transplantation centers and the local doctors and hospitals attended by patients
for their ongoing aftercare.
«
Lung transplantation is a life - saving, resource - intensive intervention for patients with end - stage lung disease,» said Joshua Mooney, MD, instructor of medicine at Stanford and lead aut
Lung transplantation is a life - saving, resource - intensive intervention
for patients with end - stage
lung disease,» said Joshua Mooney, MD, instructor of medicine at Stanford and lead aut
lung disease,» said Joshua Mooney, MD, instructor of medicine at Stanford and lead author.
It is the first animal to hit a milestone, set nearly 20 years ago by the International Society of Heart and
Lung Transplantation,
for determining whether a xenotransplantation approach is safe enough to try in humans, Brenner notes.
In this study, Danny F. McAuley, Gerard F. Curley, Umar I. Hamid, John G. Laffey, Jason Abbott, David H. McKenna, Xiaohui Fang, Michael A. Matthay, and Jae W. Lee looked at whether
lungs that were rejected
for transplantation because of edema could be «reconditioned» to qualify
for transplant.
They studied donor
lungs that had been rejected
for transplantation by the Northern California Transplant Donor Network and that were cleared
for research use by the donors» families.
The research highlights the potential
for MSC administration as a therapy
for resolving pulmonary edema and improving donor
lungs before
transplantation.
«Access to
lung transplantation for shorter lung transplant candidates could be improved by reformulating the LAS [Lung Allocation Score] calculation to provide greater transplant priority for this disadvantaged group,» Sell s
lung transplantation for shorter
lung transplant candidates could be improved by reformulating the LAS [Lung Allocation Score] calculation to provide greater transplant priority for this disadvantaged group,» Sell s
lung transplant candidates could be improved by reformulating the LAS [
Lung Allocation Score] calculation to provide greater transplant priority for this disadvantaged group,» Sell s
Lung Allocation Score] calculation to provide greater transplant priority
for this disadvantaged group,» Sell said.
It came back, but he has had to endure four cornea
transplantations, and is on a waiting list
for a new pair of
lungs.
Splitting his time between the Karolinska Institute and Kuban State Medical University in Krasnodar, Russia, Macchiarini says he is now also engineering tissues of the
lung, heart, and other thoracic organs
for transplantation.
UT Southwestern was one of 16 medical centers across the country — and the only one in Texas — participating in a national clinical trial of the technology, which was aimed at significantly expanding the number of donor
lungs available
for transplantation.
The work was supported by the National Institutes of Health, the Burroughs Wellcome Foundation, the California Institute of Regenerative Medicine, the Howard Hughes Medical Institute, the International Society
for Heart &
Lung Transplantation and a European Society
for Organ
Transplantation - Astellas Study and Research Grant.
We performed histological examination of GVHD target organs (liver,
lung, small intestine, and colon) and the tongue, which served as a surrogate
for skin damage (37), 4 wk after
transplantation.
Columbia University researchers used a new technique to rescue damaged donor
lungs and maintain their viability
for transplantation for several days.
Artificial
lungs for acute respiratory insufficiency but also
for end - stage
lung diseases, either
for the recovery of
lung function or as a bridge to
lung transplantation.
Many technological innovations
for diagnosis and treatment are expected to reach the clinic following validation, such as video - assisted thoracic surgery, sensitive imaging techniques, use of tracer gases, regenerative medicine (e.g. in
lung transplantation), nanoparticle - based carriers of inhalational drugs or bioactive compounds, personalised medicine (especially
for lung cancer), bronchoplasty, laser energy as a surgical tool, and metabolic imaging techniques.