Janssen GPH will also prioritise work with the International Partnership for Microbicides developing the investigational drug dapivirine for use as a monthly vaginal microbicidal ring designed to prevent sexual transmission of HIV and continue its pact with Drugs for Neglected Diseases initiative for the preclinical research of a reformulated form of flubendazole
for lymphatic filariasis (elephantiasis) and onchocerciasis (river blindness), Janssen GPH is also developing a new, chewable formulation of Vermox (mebendazole) that will facilitate treatment of intestinal worms in younger children.
(MDA has long been used
for lymphatic filariasis and other parasitic diseases but has a checkered history with malaria.)
Not exact matches
On Monday, the 2015 Nobel Prize in Physiology or Medicine went to William Campbell of Drew University in Madison, New Jersey, and AAAS member Satoshi Ōmura of Kitasato University in Tokyo, who will share half the prize
for discovering the drug avermectin, which has been used to treat river blindness and
lymphatic filariasis as well as other parasitic diseases.
Urbanization and the resulting shrinkage of green spaces in cities can be considered a boon
for mosquitoes that transmit diseases, such as Aedes aegypti (dengue) and Culex quinquefasciatus (
lymphatic filariasis).
Use of this technology to exclude patients from ivermectin - based treatment at the point of care in Loa - endemic regions would allow resumption / expansion of mass drug administration programs
for onchocerciasis and
lymphatic filariasis in Central Africa.