Sentences with phrase «for markers of disease»

Searches for markers of disease genes can be done without genetic maps of the relative order and distance between markers, but will be more efficient as maps with small distances between markers (high resolution maps) become available in the future.

Not exact matches

Think of people declining to get tested for the genetic markers of a hereditary disease, or a smoker whose cigarette packs might as well have that warning from the Surgeon General printed in invisible ink.

As well, many other gene markers for grain - mediated injury have been described, thus placing many into the category of gluten intolerant, but not truly having celiac disease.

The Malaysian researchers were aware of how reheated oils used over and over in deep fat fryers create hypertension (high blood pressure) and other markers for cardiovascular disease.

The Atlanta - based Centers for Disease Control and Prevention, the federal agency that collects data on a range of other health markers, only started tracking breastfeeding statistics in 1994.

A new study of 635 children in Massachusetts found that a bigger waist size at age 3 increases the odds that a child will have a marker for liver damage and nonalcoholic fatty liver disease by age 8.

Individuals were classified as high risk for Alzheimer's if a DNA test identified the presence of a genetic marker — having one or both of the apolipoprotein E-epsilon 4 allele (APOE - e4 allele) on chromosome 19 — which increases the risk of developing the disease.

Now with an extensive and diverse collection of representative apple genomes, thorough and careful analyses have allowed Fei's group to distinguish important genetic markers that will greatly aid breeders in their quest for better apples — be it for disease resistance, shelf - life, taste, or even size.

The company wanted to use it as a diagnostic marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.

«It's good to see this type of study advance, as we desperately need noninvasive and low - cost markers for Alzheimer's disease,» Hendrix says.

The marker of antigens produced by pancreatic cancer has a low positive predictive value for identifying early stage disease.

In other words, she says, personality constructs emerging from the basic biology of the brain can be yet another marker that the individual is at risk for TILT, and easier to sensitize to the disease.

«We hope that our work will provide the basis for a larger study of patient samples that may ultimately identify biomarkers that can be used as surrogate markers to determine the benefit of therapeutic interventions in diagnosed but asymptomatic HD patients to prevent or delay disease onset.»

The researchers analyzed how the changes affected indicators of cardiovascular health, such as blood pressure, heart rate and other markers for heart disease and stroke, like high «bad» cholesterol levels.

Although tau imaging is still in its earliest stages, Ryan hopes that such imaging will accelerate drug development and that finding a blood - based biomarker for Alzheimer's to reveal risk (much like cholesterol serves as a marker for cardiovascular risk) will change the field dramatically in terms of how doctors can diagnose the disease.

«Our analysis suggests that migraine should be considered an important risk marker for cardiovascular disease, particularly in women,» concludes Prof. Kurth, adding that: «The risk of developing cardiovascular events was shown to be 50 % higher in women with a diagnosis of migraine.

The concentration of these components can be a differentiating marker between certain bowel diseases and their accurate detection by way of non-invasive devices such as the electronic nose would be a great step forward for the detection and monitoring of the evolution of these diseases,» explains doctor Pilar Nos, Head of the Digestive System Medicine Department at La Fe hospital.

«This opens a new door in identifying biological markers for dementia since we might consider using the brain's processing of speech sounds as a new way to detect the disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University of Toronto's psychology department.

For neuroscientists finishing a Ph.D. program or a postdoctoral position, the mysteries of neuronal circuits and genetic markers for disease pale compared to one puzzling question: Where are the joFor neuroscientists finishing a Ph.D. program or a postdoctoral position, the mysteries of neuronal circuits and genetic markers for disease pale compared to one puzzling question: Where are the jofor disease pale compared to one puzzling question: Where are the jobs?

As a result, the emphasis in early development is on understanding the molecular underpinnings of disease and developing markers for therapeutic effects.

These discoveries build upon previous findings about genes linked to Alzheimer's, such as the APOE - 4 gene, which is a powerful marker for late - onset Alzheimer's disease; about 40 percent of those diagnosed have this DNA variant.

As Maurizio Battino, researcher at UNIVPM and Director of the study, said: «This is the first time a study has been published that supports the protective role of the bioactive compounds in strawberries in tackling recognised markers and risk factors for cardiovascular diseases.»

The study also found distinct blood pressure patterns from ages 18 to 55 that reveal people at high risk for calcification of coronary arteries — a marker for heart disease — by middle age.

«Our study suggests that short height in children is a possible marker of stroke risk and suggests these children should pay extra attention to changing or treating modifiable risk factors for stroke throughout life to reduce the chances of having this disease,» said senior study author Jennifer L. Baker, Ph.D., associate professor in the Center for Clinical Research and Prevention at Bispebjerg and Frederiksberg Hospital and Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, at the University of Copenhagen, in Denmark.

A detailed understanding of how TSPO binds to such markers opens up novel paths for diagnostic imaging and could constitute an important step along the way to early detection of such diseases and inflammations.

By providing clues to the function of proteins, he says, the Atlas may accelerate their use as markers for disease or drug targets.

Our results pointed to three new genetic markers for FECD and confirmed the vital role of a previously known marker even among those who did not have a previously known family history of the disease.

While rapid point - of - care tests for diagnosing sexually transmitted infections are commercially available today and used within developing regions, they tend not to be affordable or accurately quantify the concentrations of the disease markers within a sample, which help to determine the stage of the infection.

They also evaluated the blood for insulin resistance and two markers of inflammation that are connected with disease.

Now he looks at a whole range of possible genetic markers for the disease, in every patient taking part in every AD drug trial.

«Women with migraines have higher risk of cardiovascular disease, mortality: Migraine should be considered an important risk marker for cardiovascular disease, say experts.»

While attending a conference, Orszag learned from biologist Craig Venter that he could get screened for a genetic marker that can raise the risk of heart disease when lots of caffeine is consumed.

«We've got a marker for biological aging — telomere length — so we're studying whether we can relate it to the increased risk of getting some of these age - associated diseases.

«Our ability to pinpoint CRP levels as being significantly elevated before and after postoperative delirium onset establishes CRP as a risk marker, as well as a disease marker, for delirium,» said Sarinnapha Vasunilashorn, co-first author of the study, along with Simon Dillon, also of BIDMC.

«The distinct neural markers associated with cognitive performance and GWI revealed in our study can be useful for future research to objectively measure the efficacy of treatments for GWI as well as other brain disorders related to the same neurotransmitter system, like Alzheimer's disease.»

Similar experiments could identify new markers of diseased tissue or new targets for targeted molecular therapies.

Replicating Venter's $ 70 million technological feat is too costly for most of us, and it's not clear what good it would serve to know that, like Venter, one has a genetic marker for wet earwax — or Alzheimer's disease, which can't be prevented or cured.

Researchers at the Ludwig - Maximilians - University, the German Center for Neurodegenerative Diseases (DZNE), and the Institute for Stroke and Dementia Research (ISD) in Munich, Germany, have identified a brain inflammation marker in patients at early asymptomatic stages of Alzheimer's disease.

A selection of Joe Davis's colorful «prayer flags,» which are printed with the code for the genetic markers of diseases such as cancer, Parkinson's and Huntington's.

The researchers assessed the blood and urine samples of 70 people with the relapsing - remitting form of MS to check for levels of salt; a marker of inflammatory activity called creatinine; and vitamin D, low levels of which have been linked to the disease.

The first big advance occurred in the early 1990s, when epidemiological studies revealed that 90 to 95 percent of individuals with the disorder carry a genetic marker associated with autoimmune disease — self - inflicted damage that occurs when the body mistakes its own tissues for a foreign invader and attacks them.

Monitoring the levels of GARP on B cells may provide a very useful diagnostic marker for autoimmune disease.

These findings also suggest that other microRNAs may also be important markers of severity for other neurological diseases such as Parkinson's disease and Alzheimer's disease.

Second, fibrosis is a marker of progression to chronic kidney disease, suggesting that the paracrine effects could act as preventative therapy for other serious ailments.

These recommendations are based largely on a body of research that links higher sodium intakes to certain «surrogate markers» such as high blood pressure, an established risk factor for heart disease.

A protein known as suPAR has been identified in recent years as both a reliable marker for chronic kidney disease and a pathogen of the often deadly condition.

«We urgently need markers to predict which therapies are going to be effective and which will not be effective in individual patients with advanced prostate cancer,» said lead study author Emmanuel Antonarakis, MD, an assistant professor of oncology and urology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7 testing may be extremely valuable in guiding treatment decisions for men with hormone - resistant disease in the near future.»

The researchers note that CD8 + T cells could potentially be used as markers for the progression of fatty liver disease, which is expected to become the leading indication for liver transplantation within the next one or two decades.

These findings also suggest that other microRNAs may also be important markers of severity for other neurological diseases such as Parkinson's and Alzheimer's.

«While we don't know which comes first — depression or cardiovascular disease — the consensus is that depression is a risk marker for cardiovascular disease, meaning if you have cardiovascular disease, there is a higher likelihood that you could also have depression, when compared with the risk in the general population,» said Victor Okunrintemi, M.D., M.P.H., a research fellow at Baptist Health South Florida in Coral Gables, Florida, and lead author of a pair of studies that looked into different aspects of depression and cardiovascular disease.