You should have a passion
for medicinal chemistry and enjoy and excel at making molecules using modern methods of organic synthesis.
Not exact matches
«We're not only about discovery science but also translation science from which we can derive benefits
for mankind,» explains Mark von Itzstein, executive director of the Institute
for Glycomics and professor of
medicinal chemistry and federation fellow at GriffithUniversity.
«
For 20 years we have been using rational bioengineering to modify the chemical structures of clinically important natural products — using genetics to make a new molecule in a process that parallels
medicinal chemistry — and that's what we were doing when we stumbled upon this,» said Professor Barrie Wilkinson from the John Innes Centre.
A postgraduate
medicinal chemistry course has been proposed at the National University of Singapore that will aim to help meet an anticipated increase in demand
for chemists.
The use of halogen atoms is a promising approach
for compound optimization in
medicinal chemistry.
After the initial screening, potential «hits» were optimized by
medicinal chemistry and tested
for potency, specificity, and toxicity.
It's becoming clear and clearer as people look at different stages of the plant's growth and in different habitats growing next to other plants that the stressors in the environment can really change the
chemistry; because most of the
medicinal compounds in the plants are what are called secondary compounds, so they are not things essential to the metabolism of the plant like sugar and water and ATP
for energy and DNA.
His research interests include
medicinal chemistry, nanotechnology, drug delivery, cell trafficking and molecular imaging
for theranostic applications in cancer and Alzheimer's disease (AD).
Sumit Chanda, Ph.D., professor and director of the Immunity and Pathogenesis Program at Sanford Burnham Prebys Medical Discovery Institute (SBP), and Anthony Pinkerton, Ph.D., director of
medicinal chemistry at SBP's Conrad Prebys Center
for Chemical Genomics, are collaborators on the effort.
Liu, J., Yu, L. F., Eaton, J. B., Caldarone, B., Cavino, K., Ruiz, C., Terry, M., Fedolak, A., Wang, D., Ghavami, A., Lowe, D. A., Brunner, D., Lukas, R. J., Kozikowski, A. P. Discovery of Isoxazole Analogs of Sazetidine - A as Selective alpha4 beta2 - Nicotinic Acetylcholine Receptor (nAChR) Partial Agonists
for the Treatment of Depression, Journal of
medicinal chemistry 2011 54, 7280 - 7288
Taken together, these data suggest that indole derivatives, although their IC50 values are in the micromolar range, represent functional leads
for further development of novel CXCR4 antagonists useful in
medicinal chemistry programs.
In September the University of Kansas announced he would receive the 2018 Edward E. Smissman Lectureship
for outstanding contributions to
medicinal chemistry and molecular pharmacology.
Our projects are based on chemical biology (use of chemical molecules
for understanding biological phenomena) and
medicinal chemistry (compounds with therapeutic properties).
«To turn them into real therapeutics
for testing, we will now optimize their properties through
medicinal chemistry, so they are stable in the body, enter the brain, and safely engage the correct target in this fragile organ.»