Microbiome Helper: a Custom and Streamlined Workflow
for Microbiome Research — André M. Comeau — mSystems — January 2017
The UMI will provide oversight and guidance about how federal agencies, private foundations and commercial entities should direct funding
for microbiome research.
Not exact matches
As I've said, there have been a number of
research papers of late, led in large part by the work of French scientist Laurence Zitvogel, that are building a strong case
for a central role
for the
microbiome in cancer treatment response.
Edwardson will conduct
research primarily in Shedd Aquarium's Microbial Ecology Lab, the headquarters
for the Shedd Aquarium
Microbiome Project.
Shedd Aquarium's
Microbiome Project is ideal
for this
research since it's the world's first comprehensive look at
microbiomes in a controlled aquarium ecosystem.
Stay tuned
for a future interview by Anne, with some of the
research scientists attempting to supplement the
microbiome of infants delivered by planned Cesareans.
Emerging
research shows that bacteria are absolutely vital
for human health, and science has linked an imbalance in the human
microbiome with multiple chronic non-transmissible diseases.
For instance, recent
research strongly suggests that in modern urban populations, the human
microbiome has undergone major changes since the Industrial Revolution.
This opens the door to connecting human
microbiome samples between databases, which has the potential to expose sensitive subject information —
for example, a sexually - transmitted infection, detectable from the
microbiome sample itself,» said lead author Eric Franzosa,
research fellow in the Department of Biostatistics at Harvard Chan.
This is a highly limiting factor
for research, because it complicates the annotation of data obtained by molecular techniques, and because it has been shown that gut
microbiomes are to some extent specific to their host, and researchers have been using strains of other origin in mouse models.
The newfound role of the soil
microbiome — the collection of microscopic bacteria, fungi and archaea that interact with plant roots — represents a turning point
for research aimed at understanding and predicting where important tree species will reside in the future.
As noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art
research in both animal models as well as humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential
for psychiatric medications to directly affect the gut
microbiome.»
Through projects at Duke Health, DCRI and the Duke Center
for Childhood Obesity
Research, Armstrong and other Duke scientists are assessing the most effective strategies to reduce obesity in children, including programs that offer at - risk children access to free medical care, partnerships with municipal recreation programs across North Carolina, and even studying children's gut bacteria to determine how the gut
microbiome is related to weight.
(See here
for more on the reach of
microbiome research these days.)
Such fundamental
research while still in its early stages may pave the way
for novel therapeutic strategies in time as the
microbiome is far more manipulable than our genome.
«The fact that the virome has been overlooked
for 10 years is the elephant in the room in
microbiome research,» says Dutilh.
Alkek Center
for Metagenomics and
Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Research on
microbiome links to obesity,
for instance, suggests that a new «skinny»
microbiome has to be accompanied by a switch to a diet lower in fat and calories, or else the new microbes will just be outcompeted.
Thackray says additional
research is needed to determine whether specific gut bacterial species contribute to the development of PCOS and whether the
microbiome offers potential pathways
for treating the condition.
In the end, this
research could lead to new strategies
for manipulating the
microbiome to improve intestinal health and decrease age - associated inflammation.
«Many of the fungi most commonly detected in stool samples are also present in food or in the mouth,» said lead study author Thomas A. Auchtung, Ph.D., a senior scientist at the Alkek Center
for Metagenomics and
Microbiome Research at Baylor College of Medicine in Houston.
«Based on our
research, we identified more than a dozen microbes with known links to health that are heritable,» says Ley, also director of the Department of
Microbiome Science at the Max Planck Institute
for Developmental Biology in Tübingen, Germany.
Determining exactly who has or is at risk
for the disease is a critical unmet medical need,» said first author Rohit Loomba, MD, professor of medicine in the Division of Gastroenterology, director of the NAFLD
Research Center and a faculty member in the Center
for Microbiome Innovation at UC San Diego.
Although amplicon has been the traditional workhorse
for studies on microbial life, the spike in human
microbiome research inspired many scientists to switch to shotgun, which is cheaper and generates more genetic information.
Tags: animal
research, bacteriology, biosciences, chemistry, food,
microbiome, School of Medicine and Public Health, Wisconsin Institute
for Discovery
In recent years, there's been a boom in
research on the human
microbiome, the universe of microbes that live on and within our bodies, as scientists uncover its importance
for our health.
So the findings of our
research are quite hopeful; they suggest that our
microbiome could be a powerful means
for improving our health.»
Part of the NIH's Roadmap
for Medical
Research, the Human
Microbiome Project will award a total of $ 115 million to researchers over the next five years.
Washington, D.C. — May 13, 2016 — In support of a National
Microbiome Initiative launched by the White House Office of Science and Technology Policy and to accelerate discovery in the field of microbiome research, The Kavli Foundation has committed $ 1 million to a Kavli Microbiome Ideas Challenge supporting development of next generation scientific tools for investigating life on a microb
Microbiome Initiative launched by the White House Office of Science and Technology Policy and to accelerate discovery in the field of
microbiome research, The Kavli Foundation has committed $ 1 million to a Kavli Microbiome Ideas Challenge supporting development of next generation scientific tools for investigating life on a microb
microbiome research, The Kavli Foundation has committed $ 1 million to a Kavli
Microbiome Ideas Challenge supporting development of next generation scientific tools for investigating life on a microb
Microbiome Ideas Challenge supporting development of next generation scientific tools
for investigating life on a microbial scale.
With Helmsley funding, CCFA's
research consortium is now looking to identify potential therapies
for development by pharmaceutical companies while also conducting a rigorous investigation of the effect of diet on the
microbiome and how that might allow patients to alter the course of their illness without taking medications.
The UMIC is calling
for investments in new
research tools and cross-disciplinary collaborations that will one day allow us to predict and manage the behavior of
microbiomes.
Other investigators on this study were Caitlin E. Millett, graduate student, psychiatry and neural and behavioral sciences; Dahlia Mukherjee, postdoctoral fellow, and Aubrey Reider,
research assistant, in the Department of Psychiatry, and Shannon L. Kelleher, an associate professor of cellular and molecular physiology, pharmacology, and surgery; Adem Can, University of Maryland School of Medicine; Maureen Groer, University of South Florida, School of Nursing, and Innsbruck Medical University, Austria; Dietmar Fuchs, Innsbruck Medical University, Austria; and Teodor T. Postolache, University of Maryland School of Medicine, Rocky Mountain Mental Illness Research, Education and Clinical Center (MIRECC), and The Military and Veteran Microbiome Consortium for Research and Education, MVM &mdas
research assistant, in the Department of Psychiatry, and Shannon L. Kelleher, an associate professor of cellular and molecular physiology, pharmacology, and surgery; Adem Can, University of Maryland School of Medicine; Maureen Groer, University of South Florida, School of Nursing, and Innsbruck Medical University, Austria; Dietmar Fuchs, Innsbruck Medical University, Austria; and Teodor T. Postolache, University of Maryland School of Medicine, Rocky Mountain Mental Illness
Research, Education and Clinical Center (MIRECC), and The Military and Veteran Microbiome Consortium for Research and Education, MVM &mdas
Research, Education and Clinical Center (MIRECC), and The Military and Veteran
Microbiome Consortium
for Research and Education, MVM &mdas
Research and Education, MVM — Core.
OpenBiome was founded to expand safe access to fecal transplantation
for patients with recurrent C. difficile infection and to catalyze
research on the role of the
microbiome in human health.
Ideas
for novel tools and methods will be broadly applicable across the many environments studied in
microbiome research — the earth's soils, ocean and freshwater environments, and atmosphere; as well as animal hosts» gut and skin ecosystems.
October 28, 2015 — A consortium of 48 scientists from 50 institutions in the United States has called
for an ambitious
research effort to understand and harness
microbiomes — the communities of microorganisms that inhabit ecosystems as varied as the human gut and the ocean, to improve human health, agriculture, bioenergy, and the environment.
«
Microbiome research is a high priority
for ASM and the result of this challenge could help develop groundbreaking tools to accelerate and enhance our knowledge of
microbiomes.»
This Ideas Challenge recognizes the need
for an interdisciplinary approach to
microbiome research and invites the scientific community — including microbiologists, ecologists, chemists, physicists, engineers, material scientists, nanoscientists, computational scientists and others — to submit their ideas
for novel experimental tools and methods aimed at understanding microbial interactions and function from new perspectives.
The Human
Microbiome Project offers an opportunity to transform our understanding of the relationships between microbes and humans in health and disease,» said Dr. Alan Krensky, the director of the Office of Portfolio Analysis and Strategic Initiatives (OPASI), which oversees the NIH Roadmap
for Medical
Research.
Seres Therapeutics, Inc. (NASDAQ: MCRB) today announced that new preclinical data supporting the development of
microbiome therapeutics
for immuno - oncology (leveraging gut microbiota to impact tumor immunotherapy) 1 will be presented today by Sceneay et al in the late breaking poster session at the 2018 American Association
for Cancer
Research Annual Meeting (AACR) in Chicago.
In support of a National
Microbiome Initiative launched by the White House Office of Science and Technology Policy and to accelerate discovery in the field of microbiome research, The Kavli Foundation committed $ 1 million to a Kavli Microbiome Ideas Challenge supporting development of next generation scientific tools for investigating life on a microb
Microbiome Initiative launched by the White House Office of Science and Technology Policy and to accelerate discovery in the field of
microbiome research, The Kavli Foundation committed $ 1 million to a Kavli Microbiome Ideas Challenge supporting development of next generation scientific tools for investigating life on a microb
microbiome research, The Kavli Foundation committed $ 1 million to a Kavli
Microbiome Ideas Challenge supporting development of next generation scientific tools for investigating life on a microb
Microbiome Ideas Challenge supporting development of next generation scientific tools
for investigating life on a microbial scale.
Ideally, ideas
for novel tools and methods will be broadly applicable across the many environments studied in
microbiome research — the Earth's soils, ocean and freshwater environments, and atmosphere; as well as animal hosts» gut and skin ecosystems.
For example, research on the microbiome - the collective genomes of the microorganisms that inhabit our bodies - is yielding increasing evidence for its role in infectious disease [104], [10
For example,
research on the
microbiome - the collective genomes of the microorganisms that inhabit our bodies - is yielding increasing evidence
for its role in infectious disease [104], [10
for its role in infectious disease [104], [105].
About OpenBiome OpenBiome is the first public stool bank, founded to expand safe access to fecal transplantation
for patients with recurrent C. difficile infection and to catalyze
research on the
microbiome's role in human health.
The group of scientists who issued the call
for a «Unified
Microbiome Project» proposed a large - scale, public and private initiative to advance the science of
microbiomes through the development of new
research tools and interdisciplinary collaborations.
PrePrint: American Gut: an Open Platform
for Citizen - Science
Microbiome Research — Daniel McDonald — bioRxiv
That's why The Kavli Foundation has asked the American Society
for Microbiology, in conjunction with the American Chemical Society and American Physical Society, to select the most promising, interdisciplinary groups working on tools that could help
microbiome research.
As pressure mounts
for farmers to grow enough healthy crops to meet a burgeoning population's needs, and
for new land management strategies that improve soil carbon storage to reduce atmospheric CO2 and produce healthy soils, the soil
microbiome is the subject of more in - depth scientific
research than ever before.
Microbiome research is even important
for space exploration and planetary science.
At PNNL, she leads
research into the
microbiome, a term
for the collective communities of microbes that reside in many environmental niches, including the human gut and soil.
Zuscik, Mooney and Gill aim to collaborate with researchers in the Military and Veteran
Microbiome: Consortium
for Research and Educationat the U.S. Department of Veteran's Affairs to move this research into
Research and Educationat the U.S. Department of Veteran's Affairs to move this
research into
research into humans.