Sentences with phrase «for microcephaly»

In the case of the Zika virus, most prevalent in northeastern Brazil, there is no cure for the microcephaly that results in a baby's head being too small and the brain underdeveloped.

«Another issue that the study helps clarify is whether or not any of the recent evolutionary changes in Zika virus are to blame for microcephaly.

Recently, the Centers for Disease Control and Prevention confirmed that Zika virus is indeed the reason for microcephaly and other birth defects among babies born to Zika - infected mothers.

In tandem with the declaration, the committee made two major recommendations: Standardize surveillance for microcephaly and other neurological disorders in places where Zika is spreading, and intensify research to discern whether the clusters of cases are truly linked to the virus.

There are no treatment options for microcephaly to date.

Not exact matches

After taking samples and conducting brain scans, the researchers found that 41 percent of mothers of babies with microcephaly tested positive for Zika infection in blood or cerebrospinal fluid samples, compared with none of those whose babies did not have microcephaly.

A high proportion of mothers of both microcephaly and non-microcephaly babies also tested positive for another mosquito - borne virus, dengue fever, as well as other infections such as herpes, rubella and toxoplasma.

The concerns for the presumed exposure, infection in pregnancy, and neonatal microcephaly has led some countries in central and south America to issue travel and pregnancy warnings.

She said Brazil had registered more than 4,700 suspected cases of microcephaly and a quarter was only studied for the moment.

Investigators noted that although they could not obtain specific serological tests that would confirm ZIKV infection in these patients, all were screened for other infectious conditions that could cause microcephaly.

The Society for Maternal - Fetal Medicine released a statement on the use of ultrasound screening for fetal microcephaly following Zika virus exposure.

«Using ultrasound screening for fetal microcephaly: Statement on ultrasound screening for fetal microcephaly following Zika virus exposure.»

«We've been seeing growing evidence of the association between Zika and congenital central nervous system malformations, not just microcephaly, since the first cases were picked up,» says Wim Van Bortel, senior expert on vector - borne diseases at the European Centre for Disease Prevention and Control in Solna, Sweden.

To determine whether 25HC could protect against Zika - induced microcephaly, the researchers gave pregnant mice 25HC or placebo before and for five days after their embryos were infected with Zika virus.

Other infections also can cause microcephaly; in fact, out of 121 infants tested for other pathogens, 26 had evidence of infection with either toxoplasmosis, herpes simplex, cytomegalovirus, and syphilis.

Two of them also prove for the first time in an animal model that Zika virus can cause microcephaly in fetuses.

«The [Zika infected] cells can serve as a reservoir for a virus throughout life, and, as you can imagine, that will have a large consequence beyond microcephaly,» he said.

Take the gene ASPM, short for «abnormal spindle - like microcephaly - associated».

For example, MCPH1 and ASPM cause microcephaly when mutated, FOXP2 causes speech defects, and all three show signs of selection pressure during human, but not chimp, evolution.

The new report suggests that, as in Brazil, Zika virus bears blame for Colombia's microcephaly epidemic too.

So, given three possible explanations for what the Flores hominid is, and those three possibilities are that, you know, a dwarfed species descended from Homo erectus or an Australopithecine or a microcephalic modern human, he says that the most parsimonious diagnosis is the one that requires the fewest assumptions — would be microcephaly.

«Vaccines are an important tool for preventing Zika virus transmission and microcephaly,» said Pedro F. C. Vasconcelos, medical virologist and present director of the Evandro Chagas Institute and co-author.

While the mouse study does not prove a direct connection between Zika infection and microcephaly, Rossi said, it does underscore the urgent need for effective animal models to further study the course of disease and its transmission.

It emerged as an infectious threat in the Western hemisphere in Brazil in 2015 where it made news for creating a spate of birth defects, including the devastating brain anomaly microcephaly.

Reliable diagnostic criteria for the identification of cases of microcephaly are also still required.»

As evidence grew for a causal link between Zika infection and microcephaly and other serious congenital anomalies (1), the World Health Organization (WHO) declared the Latin American Zika epidemic a public health emergency of international concern in February 2016 (2).

Some of the severe manifestations and complications associated with Zika disease include fetal loss, microcephaly and other birth defects, and the potential for delayed mental and physical effects among infected babies born in apparent good health.

But the Brazilian government is now warning that the virus may be responsible for a dramatic increase in cases of microcephaly, a severe birth defect in which the brain fails to develop properly and the head is much smaller than normal.

Even as the Zika virus becomes more prevalent — the Centers for Disease Control reports that the number of U.S. infants born with microcephaly and other birth defects is 20 times over the normal rate — researchers are still trying to fully pin down the identifying consequences of the viral infection.

For example, to understand why a fetal brain sometimes doesn't reach full size, a condition called microcephaly, the researchers grew organoids using iPS cells derived from a person with the condition.

These findings may correlate with disrupted brain development, but direct evidence for a link between Zika virus and microcephaly is more likely to come from clinical studies, the researchers say.

The money would be a 1 - year increase to bolster health services for at - risk or infected pregnant women and babies born with microcephaly.

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known as microcephaly.

The findings — so far observed only in cells and minibrains grown in the lab — offer a possible explanation for the misshapen heads that are the hallmark of microcephaly, a condition that afflicts some babies infected with Zika.

A particular cause for concern was the increasing number of cases of brain malformations in newborns (microcephaly).

But Congress recessed for summer without approving emergency funding to combat the virus linked to microcephaly - stricken newborns.

In both of these scenarios, neural stem cells, which are crucial for normal neural development, are lost, leading to microcephaly.

Zika was known for 60 years as a mild virus that appeared sporadically, but since 2007, two troubling shifts have taken place, Dye said: Zika virus now results in widespread outbreaks of hundreds or thousands of cases, and it is associated with neurological disorders like microcephaly and Guillain - Barre syndrome, a disorder in which the body's immune system attacks the nerves.

These results collectively suggest that neural stem cells need MSI1 to generate enough neurons for normal brain size, but the presence of MSI1 also increases the vulnerability of these cells to Zika infection, leading to the death of the population which ultimately results in microcephaly.

The big Zika news this week was the announcement from the U.S. Centers for Disease Control and Prevention that yes, the virus can indeed cause microcephaly and other birth defects.

In a paper published in Nature Communications, scientists at the Institute for Research in Biomedicine (IRB Barcelona) provide molecular details about Seckel Syndrome, a rare disease that causes microcephaly, or small brain, and growth delays.

CEP63 deficiency promotes p53 dependent microcephaly and reveals a role for the centrosome in meiotic recombination

«Studies of fetuses and babies with the telltale small brains and heads of microcephaly in Zika - affected areas have found abnormalities in the cortex, and Zika virus has been found in the fetal tissue,» says Guo - li Ming, M.D., Ph.D., a professor of neurology, neuroscience, and psychiatry and behavioral science at Johns Hopkins» Institute for Cell Engineering.

For example, it recommends testing for the virus when babies have microcephaly and their mothers traveled to or lived in Zika - virus regions while pregnaFor example, it recommends testing for the virus when babies have microcephaly and their mothers traveled to or lived in Zika - virus regions while pregnafor the virus when babies have microcephaly and their mothers traveled to or lived in Zika - virus regions while pregnant.

«For couples wanting to get pregnant or thinking of becoming pregnant there is a different balance of risks because of the dangers of microcephaly and congenital Zika syndrome.

There is little doubt that a strain of the virus is responsible for the surge in Brazilian babies born with unusually small heads, or microcephaly.

«It strengthens the case that Zika is a culprit behind microcephaly,» said Joseph Gleeson, an investigator for the Howard Hughes Medical Institute, who was not involved in the study.

Organoids grown from the cells of a patient carrying the gene for severe microcephaly, however, didn't grow as large because those brain regions didn't develop properly.

Structural eye anomalies (in particular, microphthalmia and coloboma), cataracts, intraocular calcifications, and posterior ocular findings have been reported in infants with presumed and laboratory - confirmed prenatal ZIKV infection; however, posterior findings have been the most prevalent.21,25,28,33,35,36,41 - 43 Case series report chorioretinal atrophy, focal pigmentary mottling of the retina, and optic nerve atrophy / anomalies.28, 34,37,41 - 43,55 Series of 20 or more infants with presumed ZIKV - associated microcephaly report ocular findings in 24 % to 55 %.28, 33,42 In one study, testing for ZIKV IgM was performed in 24 of 40 infants (60 %) with microcephaly and the results were positive in the cerebrospinal fluid in 100 % of those tested.42 The proportion of infants with ocular lesions did not differ in those with and without testing.42 In that series, first trimester maternal infection and smaller head circumference significantly correlated with the presence of abnormal ocular findings.42

Although the evidence for Zika as the cause of microcephaly is growing, absolute proof is still not available.