Sentences with phrase «for microsatellite»

A Purdue University - affiliated startup is seeking to open up access to space for microsatellite companies by modernizing a launch technique first used in the 1950s.

Not exact matches

Aborted launch of microsatellite this morning is latest failure for nation's space scientists

Although a variety of molecular methods are still in use, microsatellite DNA markers have become the marker of choice for population studies.

For the new study, which is published today in the Proceedings of the Royal Society B, Bowman and his colleagues collected samples from 38 L. mariae palms in Palm Valley and 100 L. rigida palms in the Roper, Nicholson, and Gregory rivers and compared the microsatellite markers.

Touboul is the project scientist for MICROSCOPE, a microsatellite to be launched in 2007 by the European Space Agency.

Funded by the National Zoological Gardens of South Africa, Rufford's Small Grants for Nature, and the National Geographic Society, Parusnath is developing and testing microsatellite markers similar to those used in human parentage tests to establish the genetic relatedness of Sungazers in different populations across the species» distribution.

A microsatellite is a short, repetitious sequence of DNA — CACACACA, for instance — in which the number of repetitions can change from one generation to the next and often does.

While Wells screened the Central Asian Y chromosomes for single - nucleotide mutations such as M45, Zerjal searched for a different DNA variable called a microsatellite.

That's why a particular pattern of microsatellites can profile a particular individual — to show, for instance, as Tyler - Smith and Zerjal had done shortly before embarking on their Central Asian work, that Thomas Jefferson had fathered a son by his slave Sally Hemings and that his Y chromosome had been passed down to a man living in Pennsylvania today.

«Microsatellite length and location appears to be essential for EWS / FLI to activate the oncogenic gene targets,» says Dr. Lessnick.

«Our results have revealed and characterized two classes of GGAA - microsatellites that suggest unique interactions and distinct regulatory mechanisms for distance - dependent activation and repressions.

At long range, enhancer - like microsatellites demonstrate length - dependent EWS / FLI binding, but the researchers found minimal correlation for activation and none for repressed targets.

As a young Chinese scientist, I am participating in an exchange program with Germany, having joined the Chinese - German microsatellite genome research project at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, Germany.

In 2017, the U.S. Food and Drug Administration (FDA) approved the cancer drug Keytruda (pembrolizumab) for a range of solid tumors that are either microsatellite instability - high (MSI - H) or mismatch repair deficient (dMMR).

For the study, an international team of researchers based at institutions in Spain, the United States, Canada and Australia used mitochondrial DNA and microsatellite genotypic data to investigate the levels of genetic variation and to reconstruct the history of the invasions.

It's one of the most promising techniques in weather forecasting in a generation, and is already used on government - owned constellations, including the six microsatellites that were launched in the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC), a joint project between NOAA and Taiwan.

The samples were then analyzed with a technique called polymerase chain reaction (PCR), used to amplify specific nuclear «microsatellites» for statistically measuring gene flow between the different populations and subpopulations located in the western South Atlantic (Breeding Stock A) and the eastern South Atlantic and Indian Ocean populations (Breeding Stocks B and C, and the Arabian Sea humpback whale population, respectively).

Where the mitochondrial DNA that Georgiadis analyzed provides just a single locus for comparison, Wasser's team compared up to 16 loci in each microsatellite sample — and the regional differences they found did not evaporate upon closer inspection.

The unit provides genetic testing services using a combination of both microsatellite and single nucleotide polymorphism (SNP) panels for characterizing and selecting breeders in a wide variety of inbred mouse strains subsequently used for the generation of congenic animals.

• Mouse whole genome scanning The unit offers microsatellite and SNP based Genome Scanning Services for gene identification projects, based on linkage analysis, offering coverage for a number of mouse strains (i.e. C57BL6, DBA2J, CBA, 129S6, 129P2), as well as bioinformatic analysis using suitable mouse genetic software.

In fact, the Food and Drug Administration's approval of pembrolizumab in May 2017 for adult and pediatric patients with solid tumors and high microsatellite instability, was the first time it had approved a cancer treatment based on a genetic feature rather than the cancer's location of origin.

Both cancer types demonstrate a high frequency of microsatellite instability, where the repair mechanism for DNA is broken, and mutations in POLE, a gene responsible for producing a protein involved in DNA replication and repair.

The facility's infrastructure includes a pyrosequencing genetic analyser (PyroMark ID MA) capable of quick and efficient SNP analysis of as many as 480 samples per day, in addition to all the necessary equipment for a more conventional microsatellite genotypic analysis.

The FDA approved nivolumab (Opdivo), an anti-PD-1 checkpoint inhibitor, for patients 12 years and older with relapsed colorectal cancer that is characterized by high microsatellite instability (MSI - hi).

The FDA granted accelerated approval to pembrolizumab (Keytruda, Merck) as a second - line treatment for all metastatic solid tumor types classified as MSI - hi (high microsatellite instability) or dMMR (deficient DNA mismatch repair).

To compare the breeds, the researchers analyzed the DNA samples from the cheek - swabs for subtle differences in genetic signposts, called microsatellite loci, among the dogs.

The primary tumor location was an independent prognostic marker in patients with RAS wild - type metastatic colorectal cancer after adjusting for age, gender, synchronous / metachronous disease, consensus molecular subtype, and microsatellite instability and molecular status, according to the results of an analysis (abstract 3503) of data from CALGB / SWOG 80405 presented at the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting.

Dr. Eng presented how the Genomic Medicine Institute collaborated with the Digestive Disease Institute and Pathology and Lab Medicine Institute to successfully integrate microsatellite testing and mismatch repair protein immunohistochemistry into pathology routine for all colorectal carcinomas resected on Cleveland Clinic main campus.

The Identifiler kit and the AmpF \ STR Minifiler kit (Applied Biosystems) were used for amplification of 8 polymorphic microsatellites of the nuclear genome (D13S317, D7S820, D2S1338, D21S11, D16S539, D18S51, CSF1PO, FGA).

The role of αCaMKII autophosphorylation in the establishment of alcohol addiction Alanna Easton, King's College, UK Novel age - dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research Karienn Montgomery, University of Florida, USA Microsatellite regions upstream of the vole Avpr1a gene contribute to both individual and species differences in receptor expression Zoe Donaldson, Columbia University, USA Per Genes and Addiction Stephanie Perreau - Lenz, Central Institute of Mental Health, Germany

For the remaining 14 samples, a match was nearly perfect, with only one or two of the microsatellite markers varying, typically by only one repeat unit, as might be expected through microsatellite instability within a pedigree.

Microsatellite genotypes were obtained for 203 clinical infection samples from eight locations, and Illumina paired - end sequences were obtained to yield high coverage genome - wide single nucleotide polymorphism (SNP) data for 65 clinical infection samples from four locations.

We recovered material from 42 herbarium accessions of sweet potato collected worldwide from the 17th century to the early 20th century and obtained data on chloroplast microsatellites for all of them and reliable data on nuclear microsatellites for 30 accessions.

Microsatellite markers used for screening tests are on the same chromosome as the disease gene.

The individual microsatellite data was then analyzed for the presence of segregation under a recessive model.

Flanking microsatellite markers were selected for each locus and tested in case and control pools for possible allelic differences.

Information on island - mainland comparisons of microsatellite diversity and differentiation was unavailable for island foxes and deer mice.

Previous estimates using microsatellites and an ultrametric UPGMA bootstrap consensus tree based on (δμ) 2 genetic distances with low support calculated the divergence of southern lineages (excluding San Nicolas) to be 5539 years ago and 12,000 years ago for the island fox lineage as a whole [14].

Despite the potential for circumpolar dispersal, we found significant differentiation in mtDNA diversity (FST = 0.032, p < 0.005) and microsatellite alleles (FST = 0.005, p < 0.05) among the six Antarctic Areas historically used by the IWC for management of blue whales.

More broadly, the AgTech field as a whole continued to see billions in venture capital funding, including for technologies such as microsatellites and connected sensors that can measure and verify carbon sequestration in natural and working lands.