Sentences with phrase «for molecular studies»

Biotech and digital film companies are rooting in the city via the establishment of Torrey Pines Institute for Molecular Studies and an animation studio of Domain Media Group.

The statement also makes recommendations for clinical guidance and research priorities, such as optimal choice of EGFR tyrosine kinase inhibitors (TKIs), management of brain metastasis, role of re-biopsies, and use of circulating free DNA (cfDNA) for molecular studies.

The research was supported by the Howard Hughes Medical Institute, National Natural Science Foundation of China, National Institute of Diabetes and Digestive and Kidney Diseases (Grant DK106309), National Cancer Institute (Grant CA168654), and Center for Molecular Studies in Digestive and Liver Diseases (Grant DK050306).

Not exact matches

«This technology will allow us to paint a whole chromosome and look at it live and really follow it... as it goes through developmental transitions, for example in an embryo,» study co-author Rebecca Heald, a molecular and cell biologist at UC Berkeley, said in a statement.

Tony co-founded the UW Institute for Stem Cell and Regenerative Medicine and chaired the Molecular and Cellular Hematology Study Section for the National Institutes of Health.

Straticyte is the first and only molecular diagnostic test for oral precancerous lesions that provides an objective and accurate prediction score as evidenced by retrospective clinical studies.

Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).

Boivin had studied cellular, molecular, and microbial biology for her Bachelor of Science degree at the University of Calgary in her native Canada, but, she says, «I always had an interest in archaeology.»

By looking at reproduction as both a source of cooperation and conflict between the sexes, the researchers are finding clues from this study on a behavioral and molecular level that can be an important link for solving certain unexplained causes of human infertility.

«It requires student initiative to connect with the right role model / adviser,» says Todd Evans, a professor of developmental and molecular biology and Assistant Dean for Graduate Studies and Director of the Graduate Program at the Albert Einstein College of Medicine of Yeshiva University in Bronx, New York.

«Nonetheless, the proof of concept studies we have obtained thus far are extremely encouraging, and we are confident that with proper support and efforts we could translate our findings into experimental therapeutics for a variety of solid tumors that are driven by EphA2 overexpression, including breast, lung, prostate, pancreatic, and ovarian cancers,» said Pellecchia, who serves as the founding director of the Center for Molecular and Translational Medicine at UCR.

Europe came through: Last year, Cory received a European Molecular Biology Organization (EMBO) Installation Grant for his lab in mitochondrial biogenesis, and Gülayşe won a Marie Curie International Reintegration Grant from the European Commission to study how single genes can yield different protein products in neurons.

In doing so, the team has provided a molecular dynamics tool that allows for the study of various heat transfer problems at the nanoscale, including understanding and utilizing passive liquid flows.

Editor's Note (10/2/17): Seventeen years before the Nobel Prize in Physiology or Medicine went to three U.S. scientists for their research on biological clocks, one of them, Michael W. Young, set out an account in Scientific American describing the genetic studies that identified the «molecular timepieces» that are ubiquitous throughout the animal kingdom.

Zhou, who is the director of virology and molecular biology for Microbac Laboratories, headquartered in Pittsburgh, Penn., said the study did not yet look at the survivability of Zika on hard non-porous surfaces beyond eight hours.

«A molecular atlas of calcific aortic valve disease: Study builds molecular networks of calcific aortic valve disease to identify key molecules and therapeutic targets for a disease that affects one in four older Americans.»

Rothenburg further said that on the population level, this is probably the best - known example for a host - virus coevolution in nature, but it lacked a molecular explanation until this study.

«This study is the first to demonstrate evidence for both keratin and melanosomes, using structural, chemical and molecular methods,» says Pan.

«Our aim was to explore the effect of a more acidic ocean on every gene in the coral genome,» says study lead author Dr Aurelie Moya, a molecular ecologist with the ARC Centre of Excellence for Coral Reef Studies at James Cook University.

There, I got to study tuberculosis not only on the level of macroscopic bone changes as before, but also look at the molecular level and search for the pathogen's DNA.

«These findings stimulate new avenues for cell therapy approaches for regenerative medicine,» said Douglas Millay, PhD, study senior investigator and a scientist in the Division of Molecular Cardiovascular Biology at Cincinnati Children's.

«This new study uncovers for the first time the dynamic of stem cells during wound healing and identifies new molecular players associated with skin regeneration.

The study, which is published in the journal Molecular Psychiatry, describes a possible mechanism for how the gene variant produces clinical symptoms by affecting levels of specific proteins in the brain.

SAMHD1 isn't a molecular «good guy» or «bad guy» per se, but there are cases in which blocking its activity might thwart disease progression, said Li Wu, the study's senior author and a professor of veterinary biosciences and microbial infection and immunity in Ohio State's Center for Retrovirus Research.

Since older people have greater potential for improving their fitness than younger people, a follow - up study conducted by a research group headed by doctor and molecular biologist Helmuth Haslacher from MedUni Vienna, in collaboration with Robert Winker's team from the Health and Prevention Center of the Healthcare Institution for City of Vienna employees, took blood samples from 47 marathon runners before an ergometer test, in order to carry out laboratory tests to determine levels of analytes, including inflammatory markers, muscle and liver parameters.

In a study published in the May 29, 2014, edition of Molecular Ecology Resources, Duke researchers Peter Larsen, Ryan Campbell and Anne Yoder used high - throughput sequencing on sifaka blood samples to generate sequence data for more than 150,000 different sifaka antibodies — protective molecules that latch on to bacteria, viruses and other foreign invaders in the body and fight them off before they cause infection.

«Our goal here was to understand the molecular underpinnings of an important evolutionary transition, not to create a «dino - chicken» simply for the sake of it,» said Bhullar, lead author of the study, published online May 12 in the journal Evolution.

The global scope of the study could help researchers set upper and lower limits for black carbon deposition and better account for the effects of photodegradation, a process by which sunlight alters the molecular composition over time.

Research for the study was conducted by first co-authors Dr. Ranit Kedmi and Nuphar Veiga and colleagues at Prof. Peer's TAU Laboratory, in collaboration with Prof. Itai Benhar of TAU's School of Molecular Cell Biology and Biotechnology, Dr. Michael Harlev of TAU's Veterinary Service Center, Dr. Mark Belkhe of Integrated DNA Technologies (IDT) and Prof. Judy Lieberman of Boston Chidren's Hospital and Harvard Medical School.

«In addition, there are plans for further molecular biological studies with the objective of understanding exactly how the 5 - LO inhibitors act on the leukaemic cells.»

«The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders,» says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study.

The study of molecular entanglement is an important field of study as the presence of knots affects its physical properties, for instance the resistence to traction.

«Understanding how the enzyme actually works requires the knowledge of its three dimensional molecular structure at the atomic level,» said Dr. Mueller, principal investigator for the study that used cryo - electron microscopy (cryo - EM) to reveal the enzyme at near atomic resolution.

In the study, the research team identified three distinctive characteristic regimes with regard to the degree of slip at the interface and revealed the underlying molecular mechanisms for each regime: (i) the z - to - x chain rotation mechanism in the vorticity plane in the weak flow regime, which effectively diminishes the wall friction against chain movement along the flow direction, (ii) the repetitive chain detachment - attachment (out - of - plane wagging) and disentanglement mechanism in the intermediate regime, and (iii) irregular (chaotic) chain rotation and tumbling mechanisms in the strong flow regime.

«Data from this study serves as rationale to now include dogs with spontaneous cancers in the advancement and optimization of PMed for human patients,» according to the study, Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials.

Reasoning that boosting the clock may be beneficial, Zheng «Jake» Chen, Ph.D., the study's senior author and assistant professor of biochemistry and molecular biology at John P. and Kathrine G. McGovern Medical School at UTHealth, launched a search for a clock amplitude - enhancing small molecule.

A new study published in Nature Communications by researchers from the MRC Centre for Developmental Neurobiology (MRC CDN) at IoPPN, carried out in collaboration with the Tian lab at the Rutgers New Jersey Medical School (USA), unravels how this synchrony is achieved at the molecular level.

Published in the peer - reviewed journal Systems Biology in Reproductive Medicine, the study, «Sperm RNA elements as markers of health,» from the lab of Stephen A. Krawetz, Ph.D., the Charlotte B. Failing Professor of Fetal Therapy and Diagnosis in the Wayne State Department of Obstetrics and Gynecology and Center for Molecular Medicine and Genetics, indicates that RNA found in male sperm not only shows promise as a determinant in successful live birth, it may also tell us more about the health of a child as it matures.

After finishing her Ph.D. studies in molecular biology at the Hellenic Pasteur Institute in Athens in 1998, Alexopoulou headed for the United States.

Although a variety of molecular methods are still in use, microsatellite DNA markers have become the marker of choice for population studies.

Dmitry Royhman, currently studying to get his PSM in cell and molecular biology at IIT, says, «The reason I chose to do the PSM instead of the traditional Master's degree was because the M.S. would have restricted me more toward research, and I was not sure that was the path for me.»

His laboratories at the Institute for Biochemistry II (IBC II) and at the Buchmann Institute for Molecular Life Sciences (BMLS) recently participated in another groundbreaking study of a neurodegenerative disease, ALS.

To find out, John O'Neill, a biologist at the Medical Research Council's Laboratory of Molecular Biology in Cambridge, U.K., and his team studied skin cells known as fibroblasts, which are essential for wound healing.

According to Jonathan S. Stamler, MD, a collaborator on the study and Professor of Medicine and Director of the Institute for Transformative Molecular Medicine at Case Western Reserve University, «Neither [beta - blockers nor nitrates] in their current form are ideal.»

In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cells.

Currently only a handful of known genetic mutations have been found to account for about 10 percent of glaucoma, says Liu, corresponding author of the study in the journal Human Molecular Genetics.

This new technology offers two main advantages based on the use of molecular tools to manipulate the genome: firstly, working models that had not existed up until now for the study of tumour biology and, secondly, their application will eventually allow for the study of new therapeutic targets and therapies.

The enzyme studied in this report, Tet methylcytosine dioxygenase 2 (TET2), enables a change in the molecular structure (oxidation) of methyl groups that is needed for them to be removed from cytosines.

The study proves that deliberate and random mutations can be screened for a commercial product, says Jeremy Minshull, a molecular biologist at Maxygen Inc. in Redwood City, California.

«We think we can use our molecular, rational design approaches to make a better flu vaccine for people who really need it,» says study leader Andrew Pekosz, PhD, an associate professor in the Department of Molecular Microbiology and Immunology at the Bloomberg School of Publimolecular, rational design approaches to make a better flu vaccine for people who really need it,» says study leader Andrew Pekosz, PhD, an associate professor in the Department of Molecular Microbiology and Immunology at the Bloomberg School of PubliMolecular Microbiology and Immunology at the Bloomberg School of Public Health.