Sentences with phrase «for most tumors»

Not exact matches

For instance, most common adult solid tumors that are not cured by surgical removal are resistant to chemotherapy or radiation control, yet drug therapy is frequently offered as a «possibly effective» treatment because both patient and physician want to believe it so.

Also, eating in a comparable manner to our precursors has been demonstrated on numerous occasions to offer stunning medical advantages, including counteractive action of most maladies of human progress, for example, tumor, coronary illness, Alzheimers, and other interminable conditions that are generally created by horrible eating routine and way of life.

Former President Jimmy Carter said that his most recent brain scan showed no signs of cancer, more than three months after he began treatment for four melanoma tumors.

They implemented this principle through the development and application of something they call the «Occam Plausibility Algorithm,» which selects the most plausible model for a given dataset and determines if the model is a valid tool for predicting tumor growth and morphology.

«This research represents a big step forward in understanding why some tumors are more aggressive than others and being able to predict rationally which neoantigens will be the most effective at stimulating an immune response,» said Dr. Balachandran, a member of the David M. Rubenstein Center for Pancreatic Cancer Research at MSK, and corresponding author of the companion study in Nature.

Tumor biopsies are among the most cumbersome, risky, and expensive tests in all of medicine, so it's no surprise that researchers have been trying for decades to improve them.

«Surgery is the main treatment option for patients with most solid tumors, but recurrence and metastasis remain significant problems,» says study senior author Michael Goldberg, PhD, assistant professor at Dana - Farber and Harvard Medical School.

This is particularly true for immunotherapy, in which characterization of tumor heterogeneity is essential for choosing the most effective therapy.

Glioblastoma, the most common brain tumor in adults, has no effective long - term treatment and on average, patients live for 12 to 15 months after diagnosis, according to the National Cancer Institute.

While nivolumab improved survival rates in the overall study population, it appeared to be most successful in patients whose tumors were positive for the human papillomavirus (HPV).

It was the third mass retraction at Tumor Biology, which now holds the unenviable world record for most retracted papers, according to Retraction Watch.

The IBM Watson Health unit is perhaps the most prominent, with the company for the past several years claiming that its AI is assisting major medical centers and hospitals in tasks such as genetically sequencing brain tumors and matching cancer patients to clinical trials.

Antczak says it's been thought for years that bovine papillomavirus (BPV) is the most likely culprit behind sarcoid tumors.

The findings also have potential uses for most other types of solid tumors, including those affecting the lungs and ovaries, because the same protein and enzyme are involved, François said.

Mutations in the gene BRAF are the most common mutation found in melanoma, with up to 50 percent of tumors testing positive for the mutations.

When researchers screened a library of more than 200 drugs and related compounds for activity against embryonal subtype tumor cells from three patients, the most promising results involved drugs that increased oxidative stress in tumor cells.

Most cancer patients would opt for tumor profiling even if the test revealed that they or their families were at risk for other genetic diseases, according to a Yale Cancer Center study.

The study looked for two of the most common types of brain tumors — gliomas, which are often malignant, and meningiomas, which are more often benign — in people ages 20 to 79 in Denmark, Finland, Norway and Sweden between 1974 and 2003.

«If we can define which types of mutations and changes are the critical events driving tumor growth, we will be better equipped to identify the most appropriate treatments for individual cancers.»

A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast cancer.

Glioblastoma is the most aggressive type of tumor that originates in the brain and with no curative treatments currently available, the average survival time for patients ranges from 15 to 18 months.

Patient - derived xenographs involve the implantation of tumor tissue into an immunodeficient mouse which becomes an avatar to help identify which drug or drug combinations are most likely to be effective for an individual cancer patient.

For the CRISPR trial, a UPenn - led team wants to remove T cells from patients and use a harmless virus to give the cells a receptor for NY - ESO - 1, a protein that is often present on certain tumors but not on most healthy celFor the CRISPR trial, a UPenn - led team wants to remove T cells from patients and use a harmless virus to give the cells a receptor for NY - ESO - 1, a protein that is often present on certain tumors but not on most healthy celfor NY - ESO - 1, a protein that is often present on certain tumors but not on most healthy cells.

DIPG is the most deadly brain tumor in children and currently there are no approved drugs for treating it.

Their findings confirm preclinical evidence that the agent, which is derived from salmonella flagellin, is worthy of further investigation as treatment for some of the most common and most resilient solid - tumor cancers.

For most of the solid tumors that we work with, unfortunately, once the cancer has spread to a distant place, we're at this point unable to cure those patients, although we can oftentimes improve their quality of life or make them live longer.

More discouraging news about hormone replacement therapy for menopausal women appeared in June: Women taking Prempro, the most widely prescribed pill containing both estrogen and progestin, are more likely to develop Alzheimer's and to have early breast tumors that go undetected by mammograms.

It has been known for decades that warfarin, the most widely used anticoagulant worldwide, reduces tumor metastasis in model systems.

For most available T cell immunotherapies, T cells (which play a central role in defending the body against illness) are engineered to recognize and eliminate tumors, but their activity is not specifically controlled, leading to toxicity and unwanted side effects in patients as a result of inflammation or in some cases suboptimal response to treatment.

The new findings could help physicians prescribe the most effective treatments for each patient based on how genes are activated in the individual tumor.

«Being able to safely take tissue samples will also allow us to test for specific tumor sub-types and better decide the most appropriate treatment for each individual patient,» added Dr Booton.

The authors cite tumor heterogeneity as the most likely reason for the success of their variance - based approach.

Most of the cells that made up the tumors were positive for CA125, but the researchers found a small population that were negative and focused on those, Janzen said.

In the Oncogene study, the research team found key distinctions in how these mutated genes give rise to PLGGs, a varied group of cancers that collectively account for the most common brain tumor in children.

«Level III IVC tumor thrombectomy for renal cancer is one of the most challenging open urologic oncologic surgeries,» explained Inderbir S. Gill, MD, of the USC Institute of Urology, part of Keck Medicine of USC in Los Angeles, CA.

It is the most common malignant brain tumor in adults and accounts for about 22 percent of all brain cancers.

Glioblastomal tumors make up about one - quarter of the cases of brain cancer, and most patients survive for no more than 18 months past diagnosis.

That's enough time for the immune cells to find even the most hidden tumor.

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor - related deaths.

A new study published in the Oct. 9 issue of the journal Nature Medicine demonstrates, for the first time, that glioblastoma (GBM), the most common and most lethal brain tumor, is driven by two distinct subsets of cancer stem cells.

«We also need to integrate PIK3CA mutation analysis of breast tumors into routine practice so that we can ensure women receive the most appropriate neoadjuvant therapy for their tumor type.»

«Metastatic brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the brain and account for about 40 percent of advanced melanoma metastases.

Kaplan - Meier analysis demonstrated that most of the mice injected with cells expressing wild - type PREX2 or GFP exhibited tumor - free survival for more than ten weeks.

«Most other tumors have a mutant p53, but in these testicular cell tumors, the p53 is functioning properly, and the drugs used for testicular cancer appear to work in concert with p53's tumor suppression function to kill the cancer cells.»

«Circulating tumor cells — cells from a tumor that have escaped into the bloodstream with the potential to spread into other tissues — are extremely useful for assessing a patient's disease in order to select the most appropriate treatment,» said UBC mechanical engineering professor Hongshen Ma, the lead researcher.

«This model, when combined with a rare genetic disease, revealed for the first time how a protein known to prevent tumor growth in most cases, p53, may instead drive bone cancer when genetic changes cause too much of it to be made in the wrong place.»

«Metastatic brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the brain and account for about 30 percent of advanced breast cancer metastases,» says Khalid Shah, MS, PhD, director of the Molecular Neurotherapy and Imaging Laboratory in the MGH Departments of Radiology and Neurology, who led the study.

The authors note that «these observations emphasize the importance of integrating RNA - seq data with tumor genomes,» although this claim would have been far better supported if one did not have to dig through a massive / disorganized Excel file for most of the RNA - seq data.

Childhood Solid Tumor Network offers the world's largest and most comprehensive collection of scientific resources for studying pediatric solid tumors

While most types of primary brain cancer may spread within the brain, it is rare for a primary brain tumor to spread outside the brain.