Sentences with phrase «for multiple clinical studies»

Performed data collection, data review, query reporting, and query resolution activities in support of database locks for multiple clinical studies.

Not exact matches

«The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders,» says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study.

Due to the gaps in knowledge and the many unresolved questions, IQWiG still regards the use of certain forms of SCT for multiple myeloma to be acceptable only in the context of clinical studies.

«There are clearly molecular differences between African - American and Caucasian multiple myeloma cases, and it will be critical to pursue these observations to better improve clinical management of the disease for all patients,» said John D. Carpten, senior author of the study and chair of the Department of Translational Genomics at the Keck School of Medicine.

In the current study, McKeown and her colleagues analyzed longitudinal data on 1,685 middle - aged adults over a period of 14 years, obtained from the Framingham Heart Study's Offspring cohort — a National Heart, Lung, and Blood Institute - funded program that has monitored multiple generations for lifestyle and clinical characteristics that contribute to cardiovascular disstudy, McKeown and her colleagues analyzed longitudinal data on 1,685 middle - aged adults over a period of 14 years, obtained from the Framingham Heart Study's Offspring cohort — a National Heart, Lung, and Blood Institute - funded program that has monitored multiple generations for lifestyle and clinical characteristics that contribute to cardiovascular disStudy's Offspring cohort — a National Heart, Lung, and Blood Institute - funded program that has monitored multiple generations for lifestyle and clinical characteristics that contribute to cardiovascular disease.

An FDA - approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study.

This review shows uniform recognition that exercise and physical activity are safe for those with lung cancer, patients are requesting increased activity counseling, and multiple studies and reviews show potential clinical benefit in quality of life, exercise tolerance, and post-operative complications.

Over the last decade there have been multiple large studies trying to determine a clinical use for iNO in preterm neonates, but despite evidence of short - term benefit, this drug has not been shown to improve long - term outcomes in preemies.

«This study presents a novel strategy for treating multiple myeloma, and we hope to bring it to patients as part of a phase I clinical trial as soon as possible,» Hofmeister says.

Clinical trials are currently trying to do just this in multiple cancer types, but this is the first study that has shown that it might also work for colon cancer.

The study enrolled 100 patients with de novo coronary lesions 2.25 - 3.50 mm in diameter and length ≤ 27 mm in two 50 - patient cohorts for angiographic, intravascular ultrasound, and clinical assessment at nine or 24 months, with optical coherence tomography (OCT) performed in a subset of 30 patients at multiple time periods.

Other studies have demonstrated that activation of Ras is critical for multiple stages of induction and progression of metaplasia and may represent a focus for clinical intervention in gastric pre-cancer.

Cell therapy has been studied for multiple degenerative disorders and promising results from preclinical studies and clinical trials have been described for some.

«It's amazing to see studies going on at multiple locations in the Mekong region, where precise clinical measurements are being made in patients undergoing treatment for malaria, and within a few months these clinical data are connected to genome sequence data on the parasites,» says Professor Dominic Kwiatkowski, CGGH Director, as he reflects on the strength of the collaboration with TRAC.

From these cell based and clinical studies, we have developed important mechanistic ideas such as activation of protein kinase C, the role of vascular endothelial growth factor (VEGF) and selective insulin resistance as some of the basic mechanisms for the pathogenesis of diabetic microvascular and cardiovascular diseases which are now widely studied by multiple laboratories.

April 30, 2015 Clinical trial for guanabenz as treatment for Multiple Sclerosis begins enrollment Patients are now being enrolled in a clinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pClinical trial for guanabenz as treatment for Multiple Sclerosis begins enrollment Patients are now being enrolled in a clinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pMultiple Sclerosis begins enrollment Patients are now being enrolled in a clinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pclinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pmultiple sclerosis (MS) patients.

March 13, 2015 Blood pressure drug protects against symptoms of multiple sclerosis in animal models An FDA - approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study.

Multiple studies have given us bulletproof evidence that regular exercise brings significant psychological benefits — for example, one Harvard study has shown that ten weeks of strength training reduced clinical depression symptoms more successfully than traditional counseling.

The information was obtained from the Framingham Heart Study, a federally funded program that has monitored multiple generations for lifestyle and clinical characteristics that contribute to heart disease.

The manufacturer of Slendesta has backed its effectiveness for weight loss by citing and referring to multiple clinical studies.

Whereas enthusiasm for fasting is increasing, clinical relevance remains low because of insufficient human data, including almost nonexistent controlled trials (21, 33 — 36), few clinical outcomes studies (37, 38), lack of correction for inflated type I error rates from multiple hypothesis tests, and limited safety data (39 — 41).

To accomplish our mission, we serve as a «one - stop - shop» for our veterinary faculty, other campus units and study sponsors by providing clinical technical expertise, administrative support and financial oversight for small and large animal clinical trials in multiple disciplines, including (but not limited to) ophthalmology, oncology, neurology, cardiology, dermatology, diagnostic imaging, dentistry, internal medicine, orthopedics and soft tissue surgery.

The clinical trial comes on the heels of a breakthrough Zoetis - American Humane Association pilot study — Canines and Childhood Cancer: Measuring the Effects of Animal - Assisted Therapy for Pediatric Oncology Patients, Their Parents and Therapy Dogs — that confirmed the feasibility of conducting a randomized control trial using AAT in multiple settings.

Dr. Clifford was responsible for the creation of a clinical studies program at Red Bank Veterinary Hospital and brings this expertise to Hope VS. This opportunity will enable Hope VS to offer cutting technologies and novel therapies to our clients not only in oncology but multiple other specialties.

Glucosamine sulphate in particular is supported by multiple clinical studies and is approved in 70 countries as being used for cartilage support.

Responsible for assisting in the daily management of Phase 1 - Phase IV clinical studies in multiple therapeutic areas

Group Pension and Administrators (Richardson, TX) 2007 — 2010 Medical Data / Reporting Analyst • Implemented tactics to decreased time for generating specialized reports by 50 % on clinical financial research • Researched case studies needing Benefit Modelers and benchmark resulting in efficient aid in negotiations and cost analysis • Analyzed / interpreted data, problem solved, and communicated solutions for a variety of issues across multiple departments • Provided multiple solutions for cost drivers using medical related software showing cause and effect relationships

The study did not find evidence of these clinical domains being separate at a molecular genetic level, although only 1 — 2 genome - wide genetic variants were found to be nominally associated with either sub-domain (without allowing for multiple testing), and these did not replicate in an independent clinical sample of children diagnosed with ASD.