Sentences with phrase «for multiple clinical trials»

Dr. Mullin has a strong interest in clinical research and has served as a co-investigator for multiple clinical trials through the Animal Clinical Investigation network.

Not exact matches

Through talking to experts in the field over the past year, Gates said he had identified five areas of need: Understanding better how Alzheimer's unfolds, detecting and diagnosing it earlier, pursuing multiple approaches to trying to halt the disease, making it easier for people to take part in clinical trials of potential new medicines, and using data better.

A day after Collins was heard off the House floor discussing the possible sale of an Australian biotech stock, the company issued a news release further confirming its experimental treatment for multiple sclerosis had failed in clinical trials.

The value of Innate's shares tanked in late - June following a failed clinical trial for its multiple sclerosis treatment.

WASHINGTON — A day after Rep. Chris Collins was heard off the House floor discussing the possible sale of an Australian biotech stock, the company issued a news released further confirming its experimental treatment for multiple sclerosis had failed in clinical trials.

Shares plummeted Tuesday by more than 90 percent on a failed clinical trial for its multiple sclerosis treatment.

Clinical trials that specifically test ADAR1 - targeted therapeutics for their safety and efficacy against multiple myeloma are still necessary before this approach could become available to patients.

«Every day, most of us take for granted that when we will to move, we can move any part of our body with precision and control in multiple directions and those with traumatic spinal cord injury or any other form of paralysis can not,» said Benjamin Walter, associate professor of Neurology at Case Western Reserve School of Medicine, Clinical PI of the Cleveland BrainGate2 trial and medical director of the Deep Brain Stimulation Program at UH Cleveland Medical Center.

Previously, Russo oversaw international clinical trials for Sativex, an oral spray made by GW Pharmaceuticals in Salisbury, U.K., that has been approved in 27 countries for treating spasticity caused by multiple sclerosis and in Canada for certain types of pain.

«The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders,» says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study.

Researchers found that AcK1 closely resembles ShK, a peptide from a sea anemone, which has been shown to suppress autoimmune diseases and is currently in clinical trials for the treatment of multiple sclerosis.

«These very important early clinical trials could provide hope for patients with all sorts of neurologic problems that involve paralysis such as stroke, brain injury, ALS and even multiple sclerosis.»

Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco - derived carcinogen in cigarette smokers, researchers at the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter, demonstrated in a phase II clinical trial presented today at the American Association for Cancer Research (AACR) Annual Meeting in New Orleans.

For example, Matt Krause, director of human resources at CV Therapeutics, says, «Our research programs include multiple, cutting - edge cardiovascular product candidates in various stages of clinical trials and preclinical programs, all of which rely heavily on the contributions from our many B.S. - and M.S. - level scientists.»

«For patients diagnosed with MGUS, maintaining a healthy weight may be a way to prevent the progression to multiple myeloma, if further confirmed by clinical trials.»

It is critically important to understand how a genetic pathway actually functions and the consequences of interrupting it, especially in this case where there are multiple drug inhibitors of cyclin D being tested in clinical trials for breast cancer.

Inosine has also been administered in human clinical trials for multiple sclerosis and Parkinson's disease and has been proven to be safe in doses up 3000 mg / day.

The compound they discovered has spawned an experimental drug, ShK, which is about to go into clinical trials for treating multiple sclerosis (Toxicon, DOI: 10.1016 / j.toxicon.2011.07.016).

The findings are particularly noteworthy because drugs that act on the newly discovered target, a protein known as PIM1, are already in clinical trials for leukemia and multiple myeloma.

«For the past five years, TAVR has been growing in use and acceptance largely based upon clinical evidence from multiple randomized controlled trials, but these have been limited to patients at the highest risk for surgery,» said Martin B. Leon, M.D., professor of medicine and director of the Center for Interventional Vascular Therapy at Columbia University Medical Center - New York Presbyterian Hospital and co-principal investigator of the PARTNER triaFor the past five years, TAVR has been growing in use and acceptance largely based upon clinical evidence from multiple randomized controlled trials, but these have been limited to patients at the highest risk for surgery,» said Martin B. Leon, M.D., professor of medicine and director of the Center for Interventional Vascular Therapy at Columbia University Medical Center - New York Presbyterian Hospital and co-principal investigator of the PARTNER triafor surgery,» said Martin B. Leon, M.D., professor of medicine and director of the Center for Interventional Vascular Therapy at Columbia University Medical Center - New York Presbyterian Hospital and co-principal investigator of the PARTNER triafor Interventional Vascular Therapy at Columbia University Medical Center - New York Presbyterian Hospital and co-principal investigator of the PARTNER trials.

«This study presents a novel strategy for treating multiple myeloma, and we hope to bring it to patients as part of a phase I clinical trial as soon as possible,» Hofmeister says.

Clinical trials are currently trying to do just this in multiple cancer types, but this is the first study that has shown that it might also work for colon cancer.

We have one of the most comprehensive CAR T cell programs in the world, with 14 CAR T clinical trials ongoing and plans to open numerous additional trials in the coming year, including for patients with multiple myeloma, prostate cancer, liver cancer and breast cancer.

But in 1995, after successful clinical trials, the FDA approved the nanodrug Doxil for treating AIDS - related Kaposi sarcoma; later, the agency extended its approved use to ovarian cancer and multiple myeloma, and in Europe doctors use it to fight breast cancer.

This page features information on multiple myeloma and immunotherapy clinical trials for multiple myeloma patients, and highlights the Cancer Research Institute's role in working to bring effective immune - based cancer treatments to people with multiple myeloma.

There are now multiple immunotherapies targeting clearance of alpha - synuclein from the brain in early - stage clinical trials, and multiple trials underway or in the works on the next generation of cell replacement therapies for dopaminergic neurons, including the TRANSEURO trial; the Summit4StemCell initiative, put together by Jeanne Loring — a researcher at The Scripps Research Institute who is exceptionally engaged with turning her research into therapies; a Japanese trial to be run by Jun Takahashi of Kyoto University in Japan (cf. here and here); and a trial centered at Memorial Sloan Kettering Cancer Center headed by cell biologist Lorenz Studer.

Methods: PD patients (n = 44) of a Phase I Multiple Ascending Dose clinical trial of PRX002 / RG7935 performed smartphone - based assessments for 24 weeks.

One secondary outcome will be immunogenicity, meaning monitoring subjects for any emergence of antibodies against the infused therapeutic antibodies themselves; additionally, «Multiple clinical and exploratory biomarkers will be assessed» in the Phase Ib trial.

This same approach is now being tested in clinical trials for people with multiple sclerosis (MS) and other autoimmune diseases in the hope that providing brand new blood cells will reset the immune system to a healthy state.

Researchers from Ruhr - University Bochum in Germany have reported that a drug currently in clinical trials for multiple sclerosis is neuroprotective in two mouse models of Huntington's disease.

Cell therapy has been studied for multiple degenerative disorders and promising results from preclinical studies and clinical trials have been described for some.

Dr. Katerina Akassoglou says a biomarker for multiple sclerosis could transform the diagnosis and care of MS, while also aiding in the development of new therapies and improving clinical trials.

«A trial of this magnitude has many moving parts: multiple contracts and co-funders, a four - drug IND, a major industry partner, a biotech firm, and six university hospitals,» said Ramy Ibrahim, M.D., vice president of clinical development at the Parker Institute for Cancer Immunotherapy.

In addition, a growing number of immunotherapy clinical trials are in place to test this groundbreaking approach on other cancers like lymphoma, multiple myeloma, and for solid tumors, through trials in glioblastoma, mesothelioma, and ovarian and pancreatic cancer.

deCODE genetics (Nasdaq: DCGN) today announced positive top - line results from its Phase I multiple dose clinical trial of DG051, which the company is developing for the prevention of heart attack.

She is an active clinical trialist, leading numerous multiple clinical trials of molecularly targeted agents for advanced cancer patients.

It is currently being utilized for enrollment in multiple international clinical trials.

April 30, 2015 Clinical trial for guanabenz as treatment for Multiple Sclerosis begins enrollment Patients are now being enrolled in a clinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pClinical trial for guanabenz as treatment for Multiple Sclerosis begins enrollment Patients are now being enrolled in a clinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pMultiple Sclerosis begins enrollment Patients are now being enrolled in a clinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pclinical trial conducted to study guanabenz, an FDA - approved drug to treat high blood pressure, as a potential therapeutic to reduce loss of myelin in multiple sclerosis (MS) pmultiple sclerosis (MS) patients.

He was the founding Chairman of the Multiple Myeloma Research Consortium, Clinical Trials Core and now chairs the Multiple Myeloma Committee for the Alliance for Clinical Trials in Oncology (the former CALGB).

The new results — from trials for patients with advanced lymphoma, multiple myeloma, and pancreatic cancer — expand on Penn's work with chimeric antigen receptor (CAR) therapies, building on findings in patients with chronic lymphocytic leukemia and acute lymphoblastic leukemia dating back to the start of the first clinical trial in 2010.

Tanioka and his colleagues analyzed multiple biologic features of cancer cells from 213 patients treated for HER2 - positive breast cancer through a National Cancer Institute cooperative group clinical trial, CALGB 40601.

Whereas enthusiasm for fasting is increasing, clinical relevance remains low because of insufficient human data, including almost nonexistent controlled trials (21, 33 — 36), few clinical outcomes studies (37, 38), lack of correction for inflated type I error rates from multiple hypothesis tests, and limited safety data (39 — 41).

Not only has it been shown in multiple clinical trials to be extremely effective at promoting a healthy innate immune response, I can also personally vouch for how well it works!

Avigan and his colleagues have secured funding to perform a larger clinical trial for their leukemia vaccine, and also are conducting a trial for a vaccine against multiple myeloma, another blood cancer.

Dr. Stephenson says she is in the early stages of developing a randomized clinical trial, which is needed to validate her early findings and influence any official recommendations for women who have had multiple miscarriages.

Upon the conclusion of the pilot trial, researchers anticipate the launch of a full clinical trial across multiple sites for 12 - 18 months.

The Veterinary Center for Clinical Trials (VCCT) connected patients and referring veterinarians to investigators performing more than 60 ongoing clinical trials in multiple disciplines, including oncology, internal medicine, neurology, genetics, dentistry and dermClinical Trials (VCCT) connected patients and referring veterinarians to investigators performing more than 60 ongoing clinical trials in multiple disciplines, including oncology, internal medicine, neurology, genetics, dentistry and dermatTrials (VCCT) connected patients and referring veterinarians to investigators performing more than 60 ongoing clinical trials in multiple disciplines, including oncology, internal medicine, neurology, genetics, dentistry and dermclinical trials in multiple disciplines, including oncology, internal medicine, neurology, genetics, dentistry and dermattrials in multiple disciplines, including oncology, internal medicine, neurology, genetics, dentistry and dermatology.

To accomplish our mission, we serve as a «one - stop - shop» for our veterinary faculty, other campus units and study sponsors by providing clinical technical expertise, administrative support and financial oversight for small and large animal clinical trials in multiple disciplines, including (but not limited to) ophthalmology, oncology, neurology, cardiology, dermatology, diagnostic imaging, dentistry, internal medicine, orthopedics and soft tissue surgery.

The clinical trial comes on the heels of a breakthrough Zoetis - American Humane Association pilot study — Canines and Childhood Cancer: Measuring the Effects of Animal - Assisted Therapy for Pediatric Oncology Patients, Their Parents and Therapy Dogs — that confirmed the feasibility of conducting a randomized control trial using AAT in multiple settings.

At any given time, there are usually multiple ongoing clinical trials for dogs with these cancers at the PUVTH.