The number of symptoms and vitamin D levels had a borderline significant relationship at first, but after the analysts
adjusted for multiple comparisons, the association disappeared.
* p ≤ 0.05, ** p ≤ 0.01, *** p < 0.001, **** p < 0.0001 and non-significant (ns) p > 0.05 by Mann - Whitney test (A) and two - way ANOVA corrected
for multiple comparison using Sidak's multiple comparison test (C).
Statistical analyses were made using either Student's two - tailed unpaired t test or analysis of variance (ANOVA) as specified in the figure legends, and Newman - Keuls procedure was used
for multiple comparison analysis.
All analyses were also performed using Bonferroni corrections; we present results from analyses in which no corrections were
made for multiple comparisons since the findings were consistent.
The odds of type 2 diabetes were not statistically significant after adjustment
for multiple comparisons among the second generation, but co-corresponding author Dr. Sun Changhao, professor of nutrition and dean of the School of Public Health at Harbin, noted that these people were only in their 20s and 30s and could still be at increased risk as they age and that the research team will continue to follow up on these participants.
We then conducted multivariate (logistic) regression analyses to test the overall statistical significance of the complete set of psychosocial variables (thus
controlling for multiple comparisons).
Finally, we conducted a post hoc analysis to adjust
for multiple comparisons using the Bonferroni correction and a sensitivity analysis to determine the effect of potential unmeasured confounders.
Examining all the combinations of smoking status of parents and grandparents with the gender of the children and four different traits is quite likely to generate a chance finding of borderline significance, especially when using a series of different adjustments and not adjusting
for multiple comparisons.
For multiple comparisons, one - way ANOVA was applied, then pair-wise comparison was performed by Tukey - Kramer (Figs 1H, 4D and 5E and 5F) or Dunnett test (Fig 1I).
For multiple comparisons, one - way ANOVA with Tukey's post hoc analysis was used.
There was a suggestion of increased ASD risk among children whose mothers received an influenza vaccination in their first trimester, but the association was not statistically significant after adjusting
for multiple comparisons, indicating that the finding could be due to chance.