Sentences with phrase «for nanopore»

Benchmarking of de novo assembly algorithms for Nanopore data reveals optimal performance of OLC approaches.

Introduction to ONT devices and latest technology Wet lab training and best practices for sample quality and library preparation for Nanopore sequencing Running MinKNOW and real - time sequencing data handling Introduction to basecalling and analysis tools (ONT and opens source) for analysis of ONT data

Title: Analysis Methods for Nanopore Sequencing Data Abstract: Over the last four years nanopore - based sequencing instruments have become widely available.

For the nanopore to be effective at determining a sequence of bases, its diameter must approach the diameter of the DNA and its thickness must approach that of the space between one base and the next, or about 0.3 nanometers.

They are also being explored for nanopore sequencing applications.

In this experiment, Drndić and her colleagues worked with a different material — silicon nitride — rather than attempting to craft single - atom - thick graphene membranes for nanopores.

Not exact matches

• Oxford Nanopore Technologies Ltd, a U.K. - based developer of nanopore - based electronic systems for analysis of single molecules, raised $ 100 million pounds ($ 140 mNanopore Technologies Ltd, a U.K. - based developer of nanopore - based electronic systems for analysis of single molecules, raised $ 100 million pounds ($ 140 mnanopore - based electronic systems for analysis of single molecules, raised $ 100 million pounds ($ 140 million).

In recent years, genome sequencers have dramatically shrunk in size; Oxford Nanopore's MinION, for example, weighs only 85 grams and fits in your hand.

«Oxford Nanopore was the first announcement, but they've been roundly criticized for not showing much data,» says chemist Geoffrey Barrall, president of Electronic BioSciences in San Diego, California, which is also developing nanopore seqNanopore was the first announcement, but they've been roundly criticized for not showing much data,» says chemist Geoffrey Barrall, president of Electronic BioSciences in San Diego, California, which is also developing nanopore seqnanopore sequencing.

«By adjusting for a variety of parameters we were able to identify a pore size range, a nanopore, that best suited the purpose of the textile, one that is highly opaque visibly and at the same time highly transparent in the thermal wavelength range,» said Fan.

Using a portable, miniature DNA sequencing device (Oxford Nanopore MiniON), the researchers show for the first time that not only can the tool be used for examining environmental samples in extreme and remote settings, but that it can be combined with other methodology to detect active microbial life in the field.

Two years ago, Oxford Nanopore Technologies demonstrated a revolutionary new sequencing technology at a meeting for genomicists, but it's taken until now for it to show more data and to begin to share its new cheap, hand - held device with researchers.

The nanopore devices closest to being a commercially viable option for sequencing are made out of protein pores and lipid bilayers.

«We have shown that we can make graphene membranes and that we can pass DNA through them, a proof - of - concept for graphene nanopores,» Drndić said.

For one thing, sequencing technologies continue to develop at a breakneck pace, and, according to Willerslev, as third - generation technologies such as nanopore sequencing are applied to ancient - DNA work, researchers will be able to probe even deeper into the biological past.

Church's team at Harvard's Wyss Institute for Biologically Inspired Engineering and the Harvard Medical School developed a new electronic DNA sequencing platform based on biologically engineered nanopores that could help overcome present limitations.

I will review recent advances in the use of nanopore sequencing for clinical microbiology and human genetics, including our collaborations on viral and bacterial diagnostic sequencing, real - time surveillance, direct RNA and human whole - genome sequencing, and discuss the opportunities and barriers around moving to sequencing as a routine test in the clinic.

This presentation will review methods for which Nanopore sequencing and real - time antimicrobial resistance gene analysis can help to address the threat of CRO as a diagnostic tool in the Medical Microbiology Laboratory.

If you are interested in opportunities for academic collaboration, are a distributor, or would like to commercialize products that integrate with or are designed for use with Oxford Nanopore's products, please contact Business Development.

In this contribution, we give an example of how the controlled nanopatterning of TiO2 surfaces by BCP nanopores allows for experiments which give insight into the interactions between biological units and the nanopatterns.

Her current research is focused on developing and using nanopores as a platform for molecular sensing and manipulation.

Wijeratne noted graphene nanoribbons are already being tested for use in DNA sequencing, in which strands of DNA are pulled through a nanopore in an electrified material.

Andre Marziali, Ph.D., University of British Columbia, Vancouver $ 650,000 (3 years) «Nanopores for Trans - Membrane Bio-Molecule Detection» This group will contribute to understanding how single biological molecules interact with pores inserted into membranes, and how useful information can be derived from those interactions.

After this course you should be able to: - Prepare libraries from genomic DNA for amplicon or whole genome approaches to nanopore sequencing - Run ONT devices and assess sequencing performance during a run - Understand the basics of ONT data handling and analysis - Analyse and interpret ONT amplicon data and whole genomic data from bacterial samples

We currently operate several different types of Illumina sequencers and MinIon sequencers from Oxford Nanopore Technologies offering researchers access to cutting edge technology for high throughput sequencing for a wide range of applications.

We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly developed, web - based pipeline for real - time bioinformatics analysis on a computational server or laptop (MetaPORE).

Using nanopore sequencing, metagenomic detection of viral pathogens directly from clinical samples was performed within an unprecedented < 6 hours sample - to - answer turnaround time and in a timeframe amenable for actionable clinical and public health diagnostics.

The design and engineering of advanced solid - state nanopore materials could allow for the development of novel gene sequencing technologies that enable single - molecule detection at low cost and high speed with minimal sample preparation and instrumentation.

We developed a portable system for metagenomic analyses consisting of nanopore technology - based sequencer, MinION, and laptop computers, and assessed its potential ability to determine bacterial compositions rapidly.

We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly developed, web - based pipeline for real - time bioinformatics analysis on a computational server or la

A novel diagnostic method for malaria using loop - mediated isothermal amplification (LAMP) and MinION ™ nanopore sequencer

The MinION ™ nanopore sequencer was recently released to a community of alpha - testers for evaluation using a variety of sequencing applications.

Sara Goodwin and James Gurtowski at Cold Spring Harbor Laboratory have created error correction software for Oxford Nanopore data

Nanopore sequencing is a promising technique for genome sequencing due to its portability, ability to sequence long reads from single molecules, and to simultaneously assay DNA methylation.

IONiseR provides tools for the quality assessment of Oxford Nanopore MinION data.

We report a third - generation sequencing assay on nanopore technology (MinION) for detecting BCR - ABL1 KD mutations and compare the results to a Sanger sequencing (SS)- based test in 24 Philadelphia - positive (Ph +) leukemia cases.

NanoOk — Flexible, multi-reference software for pre - and post-alignment analysis of nanopore sequencing data, quality and error profiles

The Oxford Nanopore Technologies MinION ™ sequencer is a small, portable, low cost device that is accessible to labs of all sizes and attractive for in - the - field sequencing experiments.

Nanopore - based single molecule sequencing of the D4Z4 array responsible for facioscapulohumeral muscular dystrophy

A talk by Stephanie Hao of Johns Hopkins University Applications of Nanopore Sequencing for Infectious Disease Detection at London Calling 2016.

Speed, single - base sensitivity and long read lengths make nanopores a promising technology for high - throughput sequencing.

In this manuscript we evaluate the potential for microbiome characterization by sequencing of near - full length 16S rRNA gene region fragments using the Oxford Nanopore MinION (hereafter Nanopore) sequencing platform.

Nanopore sequencing has been available to customers for a little over three years.

Picopore: A tool for reducing the size of Oxford Nanopore Technologies» datasets without losing information.

A tool for reducing the size of Oxford Nanopore Technologies» datasets without losing information.

We report the sequencing and assembly of a reference genome for the human GM12878 Utah / Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore seNanopore Technologies) nanopore senanopore sequencer.

Dr Andrew Kilianski presents a talk for the MinION Community on Real - time Genomic Characterization of Viral Threat Agents using Nanopore Sequencing.

Nanopore sequencing, a novel genomics technology, has potential applications for routine biosurveillance, clinical diagnosis, and outbreak investigation of virus infections.

A portable system for metagenomic analyses using nanopore - based sequencer and laptop computers can realize rapid on - site determination of bacterial compositions

We present a framework for mapping cytosine and adenosine methylation with the Oxford Nanopore Technologies MinION using this nanopore sequencer's ionic currentNanopore Technologies MinION using this nanopore sequencer's ionic currentnanopore sequencer's ionic current signal.