Not exact matches
That
normal includes potential long - term health
effects from wildfire smoke, especially
for vulnerable groups like pregnant women, infants, the elderly, and people with respiratory impairment, Henderson said.
Under
normal conditions the
effect would have been
for rents to decline, with property prices following suit, leading to mortgage defaults.
In
normal market conditions, it's easy
for them to leak these type of internal discussions to see their
effect on the markets.
This way of telling Luther's story is quite conservative in its
effects, even though it presents Luther as a radical,
for it makes the present division of the Church seem
normal and inevitable to us.
These include adequate uranium supply (probably necessitating immense uranium strip mines in Tennessee), almost inconceivable reactor and waste - transport accidents, low - level radiation
effects from
normal plant operations, and the burden of guarding both radioactive waste and outdated but radioactive nuclear plants
for thousands of years.
One might argue that the
effects of human - generated pollution have altered the
normal weather patterns, but that's another argument
for another forum.
In support of this, it is to be recalled that Newton's argument
for absolute space involves certain definite ideas about forces, their
effects, and what constitutes a deformation of a
normal situation.
BIBLE says that earthquakes, hurricances, floods, plagues, locusts, etc. are caused by God as punishment
for sins SCIENCE explains that earthquakes are due to tectonic plate movements, hurricanes caused by ocean heat and coriolis
effect, floods
normal effect of weather fluctations, etc..
Recipes with
normal cocoa usually call
for baking soda to achieve a similar
effect.
Above -
normal rainfall now predicted
for California Weather officials on Monday updated a rain outlook
for the month of December, saying now that there will be above -
normal rainfall moving toward the New Year that will have a significant
effect on the drought outlook...
The young Arsenal striker Yaya Sanogo may not have scored against Hull City in the famous FA cup final triumph at Wembley back in May, but there is little doubt that he did have a big
effect for the Gunners after coming on with around half an hour of
normal time left to play.
HMRC chief executive Jon Thompson said the
effect of the court ruling essentially means that footballers playing
for British teams pay domestic tax as
normal for the income earned from their clubs.
If your preemie is now a healthy baby who had a smooth NICU course and no serious long - term
effects of prematurity, he should learn to sit up according to
normal developmental milestones
for his corrected age:
So much of putting this issue together came down to doing the research and soul - searching to really understand the differences between shame and guilt, and shame as a
normal emotion and when it crossed into unhealthy territory and the
effects of that toxic shame and then the sheer enormity of effort that must take place
for a person to heal from a shame - based self - image.»
Second, you can be sure that night wakings are entirely
normal through toddlerhood and are not associated with any ill
effects for your child.
The most recent evidence
for an
effect of infant feeding on cognitive development will be reviewed, but it will go beyond IQ, beyond just a number, and will look at the
normal brain development that happens when infants are breastfed and what developmental, educational and social consequences occur when infants are artificially fed.
«We considered that a claim that a product provided calcium «
for strong bones» implied a greater health
effect than a claim that calcium was needed «
for normal growth and development of bone».
Salk L (1960) The
effects of the
normal heart beat sound on the behaviour of the newborn infant: implications
for mental health.
This forecast assumes a «
normal» pattern
for the Liberal Democrat vote, which of course may well not be the case (the alternative of giving the Lib Dems the same incumbency
effect as found
for the other two main parties has them returning to around their 2010 vote share, which at this stage of the game seems unlikely).
Note that
normal activities may still be reasonably scrutinized
for their
effect.
The Disability Discrimination Act 1995 described a disabled person as someone with «a physical or mental impairment which has a substantial and long - term adverse
effect on his ability to carry out
normal day - to - day activities», which has or can be expected to last
for more than 12 months.
Scientists have looked
for the gravitational
effects of unidentified, star - sized objects, which could be made either of
normal matter or dark matter, known as massive compact halo objects, or MACHOs.
Others are looking
for variations in patients»
normal DNA that explain why some people tolerate radiation well, whereas others experience severe and lasting side
effects ranging from trouble swallowing and memory loss to impotence and incontinence.
IBM developed a technique
for making carbon nanotubes emit light, paving the way
for new fiber optics; Harvard scientists figured out how to deposit tiny wires on glass or plastic, opening the door
for the development of supercheap computers; and at the University of Central Florida, neuroscientist Beverly Rzigalinski discovered a nanomolecular fountain of youth
effect: When Rzigalinski applied cerium oxide nanoparticles to rat neurons in a petri dish, the particles seemed to strip out the free radicals that make tissues age and kept the neurons alive and functioning up to six times their
normal life span.
It is possible that medical advances over the past few decades in the treatment of type 2 diabetes, hypertension and high cholesterol levels have had a greater impact on people who are overweight — which increases the risk
for these conditions — whereas the
effect was much smaller in those of
normal weight.
In the lab, the antibiotics had no harmful
effect on
normal cells, and since they are already approved
for use in humans, trials of new treatments should be simpler than with new drugs — saving time and money.
In the next experiment, Karsenty looked
for evidence of such signaling
effects in osteoblasts from
normal mice.
Our data provide the first observational confirmation of this
effect, on scales much larger that what had been observed to date
for normal galaxies,» adds Dominique Sluse of the Argelander - Institut für Astronomie in Bonn, Germany and University of Liège.
«The demonstrated
effect in
normal - weight women in relation to risk
for obesity - related cancers is novel and contrary to our hypothesis,» remarked Dr. Thomson.
«Our previous studies have shown that 16 weeks of soccer training reduces blood pressure in 20 45 - year - old women with
normal blood pressure, but this is the first study that has looked at the
effects of recreational soccer in women with high blood pressure,» says Professor Peter Krustrup, who has been studying the health
effects of recreational soccer and many other forms of physical activity
for the past 10 years.
«Studies like ours can help those working with these patients: awareness of the roles played by the different factors is in fact crucial
for devising interventions aiming to minimise the
effect of the deficits and restore
normal weight levels in individuals who are already suffering because of the disease.»
Contrary to all expectations, the universe's expansion is apparently accelerating, so the inwards gravitational tug of both
normal and dark matter is being trumped by the
effect of another substance so exotic no one knows
for certain what it might be.
But the full potential of CARs
for treating solid tumors has not been reached because they have targeted molecules found on the surface of both
normal cells and cancer cells, resulting in serious side
effects.
Monitoring groups of mice, one group receiving
normal levels of protein in the diet and the other group nourished with low levels of protein
for five weeks, researchers were able to uncover the damaging
effect a reduction of protein can cause to the structure of this vital organ.
«Inhibiting DGKi seems to reverse the
effects of cystic fibrosis, but not block ENaC completely,» says Margarida Amaral from the University of Lisboa, «indeed, inhibiting DGKi reduces ENaC activity enough
for cells to go back to
normal, but not so much that they cause other problems, like pulmonary oedema.»
«More importantly, a retrovirus can infect only dividing cells such as reactive glial cells, but it does not affect neurons, which makes it ideal
for therapeutic use with minimal side
effect on
normal brain functions.»
The researchers also showed that DENV NS1 caused similar levels of blood vessel leak in
normal mice as in mice bred to have inhibited cytokine activity, suggesting that cytokines were not necessary
for this
effect.
Specifically, compared with controls, marijuana abusers had significantly attenuated behavioral («self - reports»
for high, drug
effects, anxiety, and restlessness), cardiovascular (pulse rate and diastolic blood pressure), and brain DA [reduced decreases in distribution volumes (DVs) of [11C] raclopride, although
normal reductions in striatal nondisplaceable binding potential (BPND)-RSB- responses to MP.
It's possible that inherited regions of CNV with strong influence on gene expression are targeted
for amplification / deletion by cancer cells, which might obscure their
effect in an otherwise
normal cell.
In
effect, Affigen uses cancer's «Achille's Heel»: the proteins which distinguish tumor cells from
normal cells, that can target tumor cells
for destruction with extreme sensitivity and precision.
DOYLESTOWN, Pa. (January 23, 2018)--
For decades, researchers have tried to target cancer therapies to only the cancerous cells, to avoid the toxic bystander
effects of standard chemo and radiation therapy to
normal cells.
We carefully staged wild - type (w1118) larvae at the molt to the L3, fed them
for 12 h, and then starved them
for 12 h on non-nutritive agar to eliminate the
effect of
normal fly food.
Third, two other randomised controlled trials of homocysteine - lowering treatments have shown
effects on cognition: a trial in which
normal participants with baseline tHcy levels > 13 µmol / L were treated with folic acid (0.8 mg / d)
for three years showed a beneficial
effect on several cognitive tests [44].
Under
normal conditions, deletion of the transporter does not lead to any noticeable phenotype, suggesting that pharmacological or biological blockade of the transporter
for therapeutic purposes is not likely to elicit significant off - target
effects in
normal tissues.
Although it is uncertain how much brain progranulin would need to increase
for a therapeutic
effect, reaching the lower limit of
normal, which is commonly defined as the fifth percentile of the control group (2 SDs below the control group mean), is a reasonable estimate.
Cyclotherapy is a prospective therapeutic strategy
for the protection of
normal cells from the side
effects of chemotherapy [17].
Such strategies may identify compensatory mutations that reduce the pathophysiological
effects of the risk alleles, and help determine the cellular pathways required
for the
normal function of hSERT.
To avoid this side
effect, cancer researchers have been searching
for a kinase that is active in cancer cells but not in
normal cells.
Myelosuppression is a well - established side
effect of current AML therapies, with prolonged events leading to an increased risk of infections and death.44 Consequently, therapies that preferentially kill leukemic cells over
normal bone marrow cells are urgently required, and the overexpression of CD123 on AML leukemic stem cells and blasts compared with
normal hematopoietic cells contributes to its attractiveness as a therapeutic target in this disease.6, 45 However, severe myelosuppression and myeloablation have emerged
for some investigational CD123 - targeted treatment modalities.
Importantly, IMGN632 was effective at concentrations well below those that affected
normal bone marrow cells, suggesting the potential
for efficacy in AML patients with reduced likelihood of myelosuppressive side
effects and favorable safety profile.