Sentences with phrase «for nuclear genome»

We first used in - solution capture method to enrich the DNA library for human mitochondrial DNA fragments5, 23 to screen for samples with sufficient quality for nuclear genome SNP genotyping.

Mapping and genotyping was done separately for the nuclear genome (plus chrUn) and for the mitochondrial genome.

And Pääbo calls the nuclear DNA work «really great — the way forward in ancient DNA is to go for the nuclear genome with technologies like this.»

«Also, manipulation of the embryo at that very sensitive time could cause more problems for the nuclear genome, which is why safety data is critical.»

Not exact matches

They showed that although these genomes are separate physical entities, the mitochondrial genome affects the evolution of the nuclear genome, the genetic material responsible for variations in most traits such as hair color and height.

Due to the limited number of specimens and difficulties in obtaining endogenous DNA from such old material, the number of Neandertals for which nuclear genomes have been sequenced is still limited.

«For chloroplast genome recovery from total DNA sequence data, the deliberate identification of reads that represent chloroplast DNA inserts into the nuclear genome allowed us to attain a higher - quality chloroplast genome assembly in a time - and cost - effective way,» Garaycochea explains.

In any case, however, high quality nuclear genome data from more than one individual would be necessary to fully investigate this proposed wave of human migration out of Africa, and is an intriguing area for future study.

When Pääbo's team looked at patterns of nuclear genome variation in present - day humans, it identified 12 genome regions where non-Africans exhibited variants that were not seen in Africans and that were thus candidates for being derived from the Neandertals, who lived not in Africa but Eurasia.

«Right now, the research group is analyzing the nuclear genome the results of which could provide us with information about its relationship with the Neanderthals and about the existence of genomic variations associated with the immune system that accounts for the evolutionary success of Homo sapiens over other human species with whom it co-existed.

«This method has important implications for the way future systematic studies are conducted as it provides researchers with a way to strategically target regions of interest in their study organism, such as single - copy regions of the nuclear genome or portions of organellar genomes, to produce large data sets at low costs,» says Uribe - Convers.

For the study Rand, Zhu and undergraduate co-author Paul Ingelmo generated 18 lines of flies by mixing and matching different mitochondrial and nuclear genomes in individuals from two different species.

But for flies with the same nuclear genome but the «Zim» mitochondrial genome, the balanced diet was just as good, if not slightly better than the high - sugar, low - yeast meals.

They sequenced the entire nuclear genome of this species, and identified all of the genes within that genome that code for biological functions.

An international team of scientists, led by researchers from the University of Tuebingen and the Max Planck Institute for the Science of Human History in Jena, successfully recovered and analyzed ancient DNA from Egyptian mummies dating from approximately 1400 BCE to 400 CE, including the first genome - wide nuclear data from three individuals, establishing ancient Egyptian mummies as a reliable source for genetic material to study the ancient past.

The study has solid geographical sampling, and the team's statistical analysis of two DNA genomes — mitochondrial and nuclear — shows pretty good evidence for the new species, says Bryan Stuart, a curator of herpetology at the North Carolina Museum of Natural Sciences in Raleigh, who was not involved in the work.

Researchers from the University of Seville at the Andalusian Centre for Molecular Biology and Regenerative Medicine (Centro Andaluz de Biología Molecular y Medicina Regenerativa — Cabimer) have discovered that in eukaryotic cells the proximity of the genes to the nuclear pores, which are found in the nuclear membrane, contributes to maintaining the integrity of the genome.

«For this reason, ribose - seq has application for rNMP mapping in any genomic DNA, from large nuclear genomes to small genomic molecules such as plasmids and mitochondrial DNA, with no need of standardization procedures,» she saFor this reason, ribose - seq has application for rNMP mapping in any genomic DNA, from large nuclear genomes to small genomic molecules such as plasmids and mitochondrial DNA, with no need of standardization procedures,» she safor rNMP mapping in any genomic DNA, from large nuclear genomes to small genomic molecules such as plasmids and mitochondrial DNA, with no need of standardization procedures,» she said.

Dr. Donovan Bailey, senior author of the study and professor at New Mexico State University, said this approach has several advantages over previously established methods for enriching either nuclear or organellar DNA for genome sequencing.

In addition, mitochondria contain their own genomes, which code for specific proteins and are expressed in coordination with nuclear DNA to regulate the provision of energy to cells.

Genetic differentiation for nuclear, mitochondrial and chloroplast genomes in common wild rice (Oryza rufipogon Griff.)

You are what you eat: a gene transfer ratchet could account for bacterial genes in eukaryotic nuclear genomes.

Nuclear domain «knock - in» screen for the evaluation and identification of small molecule enhancers of CRISPR - based genome editing.

«This suggests that cell division is used not only to transmit the genetic information into daughter cells and create two equivalent cells,» he said, «but it is also an opportunity for cells to reorganize their genomes in 3D space, sequestering parts of the genome at the nuclear periphery and rendering it inaccessible to transcription.»

Y - chromosome haplotypes were recovered by aligning reads against previously identified Y - chromosome contigs (12, 75), first against the contigs alone and then remapped against the full nuclear genome, including the Y - chromosome contigs, to control for repetitive regions.

In particular, diversity of the nuclear genome is unlikely to be reciprocally monophyletic among subpopulations, a phenomenon called incomplete lineage sorting, which results in support for different topologies across loci (27).

The Identifiler kit and the AmpF \ STR Minifiler kit (Applied Biosystems) were used for amplification of 8 polymorphic microsatellites of the nuclear genome (D13S317, D7S820, D2S1338, D21S11, D16S539, D18S51, CSF1PO, FGA).

Here we utilize whole - genome sequencing of Roifman Syndrome patients to reveal compound heterozygous rare variants that disrupt highly conserved positions of the RNU4ATAC small nuclear RNA gene, a minor spliceosome component that is essential for minor intron splicing.

With a given read depth of 31X, the assemblies from both Pacific Biosciences and Oxford Nanopore MinION show excellent continuity and completeness for the 16 nuclear chromosomes, but not for the mitochondrial genome, whose reconstruction still represents a significant challenge.

We are excited to announce that our successful work of backing up two mitochondrial genes into the nuclear genome has been accepted for publication in the journal Nucleic Acids Research!

(b) Archaeogenomic relatedness results for mtDNA (nucleotide sequence similarity to burial 14) and the nuclear genome.

In the absence of a population suitable for GWAS, we utilized genome - wide SNP profiles from a nuclear family to evaluate inheritance patterns in chromosomal regions harboring all 18 candidate genes.

With recent announcements of plans for sequencing the genome from present - day polar bear (34) offering a necessary reference, future sequencing of all or a substantial fraction of the nuclear genome of this exceptionally well preserved Pleistocene polar bear specimen may be feasible.