Amo1 is not required for the microtubule loading of several factors affecting microtubule dynamics, and does not seem to be required
for nuclear pore function.
Not exact matches
Researchers from the University of Seville at the Andalusian Centre
for Molecular Biology and Regenerative Medicine (Centro Andaluz de Biología Molecular y Medicina Regenerativa — Cabimer) have discovered that in eukaryotic cells the proximity of the genes to the
nuclear pores, which are found in the
nuclear membrane, contributes to maintaining the integrity of the genome.
The proximity and anchoring of the genes to the
nuclear pores during transcription has been known of
for more than a decade.
Moreover, proteins that rely on RanGAP
for transportation into the nucleus don't flow through the
nuclear pores.
It will be one of the hardest forms of damage to repair via rejuvenation biotechnology; the only one that springs to mind as likely being even more difficult is the matter of damaged
nuclear pore proteins in long - lived cells, single molecules that might be as old as you are, doing the same job
for an entire human life span.