A decade ago a drug based on an internal protein of the flu virus, called NP (
for nucleoprotein), set the immune system's killer T cells into action, but it only partially protected mice from the flu.
Not exact matches
Like many other related viruses, Ebola virus contains a negative - sense, single - stranded RNA that encodes seven different proteins, one of which is known as the
nucleoprotein (NP)
for its ability to interact with the viral RNA genome.
In December, Outi Vaarala of the University of Helsinki and her colleagues had reported that Pandemrix contained a much higher level of
nucleoprotein than a GSK vaccine called Arepanrix, which was associated with a much smaller risk
for narcolepsy.
The study also suggests ways to make influenza vaccines even safer,
for instance by keeping the
nucleoprotein levels low or removing the specific region of the protein that mimics the receptor.
Their search turned up a suspect: a piece of a receptor
for hypocretin resembles part of the H1N1 influenza
nucleoprotein — which binds to the virus genome and plays a key role in its replication.
Telomeres are
nucleoprotein complexes located at the ends of chromosomes, essential
for chromosome protection and genomic stability.
Immunohistochemical staining of the tissues was carried out
for the influenza
nucleoprotein detection in sparrows» tissues.