Sentences with phrase «for obese mice»

Both fusion proteins effectively decreased body weights for obese mice and cynomolgus monkeys.

Whole - body vibration, the activity this gym - goer is performing, provided a metabolic tune - up for obese mice.

Not exact matches

One team has found in two children mutations in the gene for the metabolic hormone leptin, which in mice tells the body it's satiated; defects in this gene had not previously been found in obese people.

Back then, Harrison restricted calories for genetically modified obese mice, which remained extremely fat even when food was cut.

Separate groups of germfree mice were colonized with uncultured fecal microbiota from each member of four twin pairs discordant for obesity or with culture collections from an obese (Ob) or lean (Ln) co-twin.

«If human offspring from obese mothers have a similar risk for developing fibrosis as we see in mice, we may be able to predict who is going to develop more serious disease,» said Thompson.

While hardly any inflammation occurred in the subcutaneous fat of obese mice and cGMP signaling was largely intact, things were very different for the deeper - lying abdominal fat: through the significant weight increase, inflammation had spread and the fat - burning turbocharger cGMP largely came to a standstill.

For example, cloned cows have faulty immune systems, and cloned mice grow obese and exhibit other abnormalities.

For example, we showed in collaborative work with Jeffrey I. Gordon's laboratory at Washington University in St. Louis last year that transferring the microbes from an obese person into mice raised in a bubble with no microbes of their own resulted in fatter mice.

In fact, metabolic benefits were almost the same for genetically obese and diabetic mice from both WBV and those exercising on the treadmill.

Meanwhile, Granier became interested in adiponectin receptors after a Japanese group showed that a small molecule could activate the receptors for to increase insulin sensitivity in an obese mouse model.

For some years an asthma drug called amlexanox has been studied for its ability to inhibit TBK1, and a previous experiment showed that when administered to obese mice, it caused weight loss and increased the animals» sensitivity to insulin, helping improve their diabetes and fatty liver diseaFor some years an asthma drug called amlexanox has been studied for its ability to inhibit TBK1, and a previous experiment showed that when administered to obese mice, it caused weight loss and increased the animals» sensitivity to insulin, helping improve their diabetes and fatty liver diseafor its ability to inhibit TBK1, and a previous experiment showed that when administered to obese mice, it caused weight loss and increased the animals» sensitivity to insulin, helping improve their diabetes and fatty liver disease.

So this mutation was referred to as the fat mouse, and then they're also referred to as the ob / ob mice; ob standing for obese.

For example, if the hypothalamus of a mouse doesn't recognize leptin, the animal will overeat, becoming obese.

Mice homozygous for the obese spontaneous mutation, Lepob (commonly referred to as ob or ob / ob), exhibit obesity, hyperphagia, transient hyperglycemia, glucose intolerance, and elevated plasma insulin.

After exercising for six weeks, both obese and lean mice showed a significant reduction in the overall size of fat cells and the overall amount fat in the marrow.

Male C57BL / 6J obese mice fed a high - fat diet for 12 weeks and genetically diabetic db / db mice at an age of 6 weeks received dietary C3G supplementation (0.2 %) for 5 weeks.

A recent study at the Salk Institute for Biological Studies in La Jolla, Calif., showed that mice that feasted on fatty foods for eight hours a day and subsequently fasted for the rest of each day did not become obese or show dangerously high insulin levels.

Activity through play is most effective with obese cats as, in addition to burning calories, it increases muscle mass, increases resting metabolic rate, improves mobility and mental stimulation, and often improves the cat — owner bond.10 Owners should be encouraged to increase their cat's activity level at home gradually, based on its needs, starting with 5 to 10 minutes per day of low - intensity activities for sedentary pets (e.g., walking).22 Creativity in activities, such as incorporating food - dispensing toys, placing meals in different parts of the house, and using interactive toys, laser pointers, and electronic mice can also be helpful with a long - term weight loss program.22 Any increase in physical activity is likely beneficial for a cat of any weight.