In today's issue of Science Translational Medicine, he and his colleagues present a more efficient way of finding such new uses
for old drugs: by bringing together data on how diseases and drugs affect the activity of the roughly 30,000 genes in a human cell.
Researchers are also looking at new uses
for old drugs — trying to prevent Alzheimer's using ibuprofen, for example.
«Computer program finds new uses
for old drugs: Researchers repurpose pain meds to kill cancer cells.»
Researchers at the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine have developed a computer program to find new indications
for old drugs.
Multi-targeted therapy of cancer by niclosamide: A new application
for an old drug.
Not exact matches
The
drug at the heart of four lawsuits in New Jersey is insulin — «a century -
old medicine that
for most of its history cost $ 15 or less,» write Barrett and Langreth, but «whose list price has risen more than 270 percent over the past decade.»
On Thursday, Bristol - Myers Squibb abruptly ditched an accelerated approval application
for a combo of its rival immunotherapy Opdivo and an
older drug called Yervoy.
As lawmakers and the public scrutinize dramatic price increases
for other
old drugs — most recently with the Mylan - owned EpiPen, which saw its cost go up by 500 % in the past nine years — the next flash point may be insulin, a
drug both ubiquitous and complicated.
In his retrial, 80 - year -
old Cosby was convicted of three counts of aggravated indecent assault,
for drugging and sexually assaulting Temple University employee Andrea Constand in 2004 at his suburban Philadelphia home, according to the Associated Press.
Williams, a 39 - year -
old Kansas City man whose long criminal record includes
drug and domestic violence charges, is serving nearly eight years in federal prison
for unlawfully transporting a firearm in a stolen vehicle.
For Alice Marie Johnson, a 62 - year -
old nonviolent
drug offender serving a life sentence without parole.
However, things changed when she went back to work
for an
old boss who had a thing
for her (and somewhat began returning the favor after her husband began spending a little too much time cooking a certain
drug).
While Yervoy brought in $ 960 million in sales in 2013 (an enormous figure
for a two - year -
old drug with a small patient population), the company currently has more than 35 ongoing clinical trials investigating another
drug that disengages the immune system's brakes: the much - awaited nivolumab, which was also from the Medarex portfolio.
In the early hours of Monday morning, French
drug giant Sanofi said it would buy hemophilia drugmaker Bioverativ, a Biogen spinout that is less than a year
old,
for $ 11.6 billion.
Which is why so many
old - guard health care companies, from hospitals and insurers to benefits managers and
drug and device makers — which together account
for one - fifth of the economy — are hastily recombining and reinventing themselves.
«This deposition and investigation are about better understanding the dramatic price increases we're seeing
for decades
old prescription
drugs and how those prices are affecting consumers — and we're committed to being thorough in that pursuit.»
Here's yet another facet of the U.S.
drug pricing conundrum:
older treatments which have been around
for years can win label expansions that significantly increase their value, and consequently, their list prices.
«While we understand a steady, rational increase in prices, it is the sudden, unfounded price explosions in select
older drugs that hinder us in caring
for patients,» Fogel told the committee.
The most anticipated event
for Biogen Idec's
drug pipeline, Friday's release of data on its experimental Alzheimer's medicine, started 12 years ago with the rekindling of an
old friendship.
Specialists in infectious disease are protesting a gigantic overnight increase in the price of a 62 - year -
old drug that is the standard of care
for treating a life - threatening parasitic infection.
EKR is getting its
old drug back
for a song.
While most of the attention on pharmaceutical prices has been on new
drugs for diseases like cancer, hepatitis C and high cholesterol, there is also growing concern about huge price increases on
older drugs, some of them generic, that have long been mainstays of treatment.
The courtroom was cleared
for arraignments in a criminal
drug and weapons case that featured a different Martin Shkreli — a Bedford, N.Y. man more than 20 years
older than the 34 - year -
old Pharma Bro — as one of the defendants.
Menlo is a seven - year -
old, Redwood City, Calif. - based
drug developer focused on severe skin itching and chronic cough, and demand
for its shares was such that it increased its proposed IPO terms from offering 5.7 million shares at $ 14 to $ 16, to offering 6.5 million shares at $ 16 to $ 17.
(i) a woman's right to choose; (ii) teaching evolution in school; (iii) medical immunization of teen girls against HPV; (iv) assisted suicide; (v) gay marriage; (vi) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» by theists (vii) basic $ ex education
for older school children; (viii) treating
drug abuse as principally a medical issue; (xi) population control; (x) buying alcohol on a Sunday; (xi) use of condoms and other contraceptives (xii) stem cell research.
A son made a decision
for Christ when he was six years
old, but then in high school got involved in
drugs and drinking, and died one night in a car accident.
Get on your computer and look up the average life expectancy
for a homeless teenager who is a
drug addict who is regularly raped by dirty
old men.
In fact most of us would be trying to scratch out a living on a farm with no modern equipment, hoping
for enough rain to produce food
for the next year, and dying at 35 yrs
old from diseases now cured by
drug companies.
The Archbishop of Manila has called
for an end to the «waste of human lives» following a brutal week in President Rodrigo Duterte's
drug war in which dozens were killed including a 17 year
old boy.
In sum, what the hippies found is that when the call to love one another isn't being matched enough by the actual feeling (and doesn't even seem to be working
for the really radical ones out on the commune), and when the life immersed in
drugs, hedonism, festivals, personal drama, and song can no longer keep one from noticing this, there's always the
old stand - by, the enemy, which can be evoked to bring «us» together.
I guess that the 8 year
old is God's collateral damge,
for I can not imagine how many abortions he might have had, bottles of Patron he might have drank, or
drugs he slammed to warrant this fate.
And while the administration of life - ending
drugs must be freely chosen by the person to be euthanized, it is obvious that the more euthanasia becomes normalized, the more coercive the cultural attitude will become
for the young and
old alike.
(i) a woman's right to an abortion; (iii) medical immunization of teen girls (and boys) against HPV; (iv) assisted suicide; (vi) gay marriage; (vii) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» Catholics; (viii) basic $ ex education
for older school children; (ix) treating
drug abuse as principally a medical issue; (x) population control; (xi) buying alcohol on a Sunday in many places; (xii) use of condoms and other contraceptives; (xiii) embryonic stem cell research; (xiv) little 10 year -
old boys joining organizations such as the Boy Scouts of America, regardless of the religious views of their parents; and (xv) gays being allowed to serve openly in the military.
(Source: Fox News) BILLINGS, Mont. — A 35 - year -
old man imprisoned
for drug possession has filed a $ 10 million federal lawsuit against Yellowstone County, alleging jailers interfered with his satanic religious practices while he was in jail.
BILLINGS, Mont. — A 35 - year -
old man imprisoned
for drug possession has filed a $ 10 million federal lawsuit against Yellowstone County, alleging jailers interfered with his satanic religious practices while he was in jail.
But the young man rubbed his eyes as if he had just woke up, and he looked towards the rays of the sun, and won the consideration of all who now had turned their attention to him;
for he no longer showed himself licentious, nor did he stare madly about, but he had returned to his own self, as thoroughly as if he had been treated with
drugs; and he gave up his dainty dress and summery garments and the rest of his sybaritic way of life, and he fell in love with the austerity of the philosophers, and donned their cloak, and stripping off his
old self modeled his life in future upon that of Apollonius.
Death by suicide,
drug and alcohol poisoning, chronic liver disease and cirrhosis roughly doubled in the fifteen - year period between 2000 and 2015
for 30 - 34 year
olds and 50 - 54 year
olds.
Walker, a 62 - year -
old human resources manager who took up powerlifting after developing osteoarthritis, set world records
for her age group (60 — 64) in the 70 - kilogram weight class
for power squat (77.5 kg), bench press (45 kg), and deadlift (112.5 kg) at the World
Drug - Free Powerlifting Federation championships in Muskegon, Mich..
I'm actually in favour of
drug testing at the elite level but
for these
old guys who really cares.
The new odor, a commingling of the vapors of turpentine, rotten eggs and
old oysters, comes from dimethyl sulfoxide, better known as DMSO, the controversial and often illegally used
drug hailed by a growing legion of amateur and professional athletes who view it as a panacea
for many ills ranging from sprained ankles to tendinitis and ripped muscles.
The
old - school wrestler detested the direction of theatrical wrestling in the late - 1980s, but moreover he held huge disdain
for a culture of steroid and illicit
drug use that he saw perverting the sport.
Before making his debut however, he has come under hot water
for apparently missing a
drugs test on Monday, when he was supposedly en route to
Old Trafford to carve out the finer details of his move this week.
* Curiosities about same sex stimulation, I think many men have these curiosities and it messes with them mentally, either they act on it or divulge in gay porn I DO NT THINK THATS TRUE UNLESS THEY ARE IN PRISON * Addiction to porn and / or jacking off ONLY WHEN GETTING IT FROM THEIR WIFE IS SUCH A CHORE * Medical Conditions such as low sex drive, he is
older and it has been going down over the years, he has high blood pressure and takes medication, he also has low Vitamin D and takes supplements, he may have some ED issues as well LACK OF SEX COULD CAUSE AS WELL AS BE CAUSED BY THOSE FACTORS * Sexual advances from other woman and him acting on those or seeking out other women
for comfort when he is angry and / or depressed A DEFINITE POSSIBILITY * His ADHD doesn't allow him to process issues normally, he is quick to anger, depression, and feeling disrespected that causes his to retreat * He was self raised, came from
drug infested household where neglect, torture, and narcissism ruled, and he lost his mother at the age of 7 from
drugs, growing up in foster care * I make more money and I control all the money, he is not interested in paying bills at all, this immaculateness him * He is a control freak and sex is his way of controlling me, where he otherwise can't control me as I am more educated and he is more vocational SOUNDS TO ME LIKE YOU ARE A MATCHED PAIR IN THAT RESPECT.
* Curiosities about same sex stimulation, I think many men have these curiosities and it messes with them mentally, either they act on it or divulge in gay porn * Addiction to porn and / or jacking off * Medical Conditions such as low sex drive, he is
older and it has been going down over the years, he has high blood pressure and takes medication, he also has low Vitamin D and takes supplements, he may have some ED issues as well * Sexual advances from other woman and him acting on those or seeking out other women
for comfort when he is angry and / or depressed * His ADHD doesn't allow him to process issues normally, he is quick to anger, depression, and feeling disrespected that causes his to retreat * He was self raised, came from
drug infested household where neglect, torture, and narcissism ruled, and he lost his mother at the age of 7 from
drugs, growing up in foster care * I make more money and I control all the money, he is not interested in paying bills at all, this immaculateness him * He is a control freak and sex is his way of controlling me, where he otherwise can't control me as I am more educated and he is more vocational
-- I have an Italian mom, which means dark, hereditary circles and hollows — I just turned 50 on July 20 — and though I try to take good care of myself and am told that I look younger than my age, these eyes are showin'the signs... — I have a 12 year
old boy with special needs and sleep is something that we do not get much of around here, which impacts my eyes (no replacement
for sleep, I know)-- I have tried many, many, many creams (
drug store brands, Estee Lauder, Lancome Genifique, Clinique, Origins, Clarins, Chanel, am trying ProX / olay right now, many others) and I have still not yet found my holy grail eye cream, nor have I ventured into trying the Perricone brand (though I've always wondered if it was worth it)
Now all of that milk goes to the home, it's almost like a
drug in California we do require physician prescription and the same quality and the same way that processing that we clean the milk
for the NICU babies, we also do that
for the
older child in the mature milk.
A 44 - year -
old South Holland woman with two «crack» pipes was charged with retail theft and possession of
drug paraphernalia and a 46 - year -
old Chicago man was charged with battery after she stole clothing retailing
for $ 130 from Macy's at Orland Square Mall and he attempted to run interference on April 9.
Baby wearing was the only thing that saved me from agony while my two year
old was
drugged up on Motrin
for her molars, which did nothing to help really.
While
drug treatments are potentially dangerous and not highly effective
for symptoms ascribed to colic or GER, one partial exception may be the
older type of acid - reducing
drugs such as Zantac, still prescribed today.
The FDA has not approved these
drugs for children under a year
old because no studies have found them effective in that population.