Imaging like ultrasound and X-rays to look
for other causes of disease and assess the appearance of the stomach and intestines
In the search
for other causes of the disease, an international team of researchers, led by Davide Calebiro, Luca Persani from the University of Milan and Ralf Paschke from the University of Calgary, have now scored a success.
Not exact matches
Important factors that could
cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability
of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential
for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost
of accommodating, announced increases in the build rates
of certain aircraft; 6) the effect on aircraft demand and build rates
of changing customer preferences
for business aircraft, including the effect
of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result
of global economic uncertainty or otherwise; 8) the effect
of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution
of key milestones such as the receipt
of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or
other third party approvals
for the consummation
of our announced acquisition
of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our
other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability
of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and
other customers, and the risk
of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production
of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts
of terrorism; 14) any adverse impact on the demand
for air travel or our operations from the outbreak
of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or
other security attacks, information technology failures, or
other disruptions; 16) returns on pension plan assets and the impact
of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price
for our announced acquisition
of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and
other aerostructures suppliers; 19) the effect
of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect
of changes in tax law, such as the effect
of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations
of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect
of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability
of raw materials and purchased components; 23) our ability to recruit and retain a critical mass
of highly - skilled employees and our relationships with the unions representing many
of our employees; 24) spending by the U.S. and
other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate
for our additional capital needs or
for payment
of interest on, and principal
of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness
of any interest rate hedging programs; 28) the effectiveness
of our internal control over financial reporting; 29) the outcome or impact
of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and
other cost savings; 32) our ability to consummate our announced acquisition
of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and
other business disruptions
for ourselves and Asco as a result
of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks
of doing business internationally, including fluctuations in foreign current exchange rates, impositions
of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among
other things.
Other than accidents and suicides, the top 10 leading
causes of death encompass stroke, Alzheimer's, diabetes, the flu and pneumonia, and kidney
disease, according to the Centers for Disease Control
disease, according to the Centers
for Disease Control
Disease Control (CDC).
Other activities include: producing products that may be recycled at the end
of their lifespan
for material reuse; reducing energy consumption in operations; or even re-engineering distribution methods as a means
of reducing long - distance travel during product delivery, ultimately reducing fossil fuel consumption (and the
disease -
causing air pollution that is its byproduct).
Contamination from upstream tar sands / oil sands development is
causing higher levels
of cancer and
other serious
disease for members
of the Athabasca Chipewyan and...
This is hypothesized to happen
for many different reasons, including a decline in the competitiveness
of other economic sectors (
caused by appreciation
of the real exchange rate as resource revenues enter an economy, a phenomenon known as Dutch
disease), volatility
of revenues from the natural resource sector due to exposure to global commodity market swings, government mismanagement
of resources, or weak, ineffectual, unstable or corrupt institutions (possibly due to the easily diverted actual or anticipated revenue stream from extractive activities).
Brian, Well I suppose I do have a fear about what these fantasy beliefs can do to
cause trouble all over the world, as if we don't have enough with real problems
of political ills, poverty,
diseases and natural disasters; but mostly I am repelled by so many, like eaglemt and the huge number
of others like him / her, who preach hell - fire and eternal torment
for those who don't regard their unproven beliefs as reality.
So the discovery
of the bacteriological
cause of paresis brought few cures; more often it only reinforced the hope that specific cures (or diagnoses inviting means
for cure) could be found
for the
other «
diseases.»
The depravity
of their cynicism astounds even a crusty old bird like me: If Golden Rice is a success and effectively reduces blindness,
disease, and death
caused by vitamin A deficiency in millions
of rice consumers, it will pave the way
for other GM food crops that may be healthier
for people and good
for the environment.
Here are some
of the
causes of constipation: a poor diet comprised
of too much animal protein and a lack
of fiber intake, not enough fluids, lack
of exercise or
other physical activity, an illness, certain drugs and medication prescribed
for other diseases or weight loss programs, colon cancer, depression, stress, anxiety etc
Excessive and unnecessary use
of the drugs, which are similar to what doctors prescribe
for people's ear infections, strep throats and
other illnesses, can lead to super-resistant strains
of bacteria that can
cause serious human
diseases that have no cure.
A far - reaching study conducted by scientists at Cincinnati Children's reports that the Epstein - Barr virus (EBV)-- best known
for causing mononucleosis — also increases the risks
for some people
of developing seven
other major
diseases.
If so, does it
cause Lyme - like symptoms, and what are the implications
for diagnosing and treating people with these
other forms
of disease?
«We're always looking
for ways to mitigate risk, and our first - time finding points to a novel environmental factor that also might help us to determine the
cause of this and
other devastating autoimmune
diseases.»
So much so that type 2 diabetes, obesity, and
other diseases of Western civilization are becoming
causes for concern there too.
Each
of these immune cells contains DNA that codes
for a protein that recognizes bacteria, viruses, allergens, cancer cells and
other potential
disease -
causing invaders.
A new strategy — an injectable antibody —
for lowering blood lipids and thereby potentially preventing coronary artery
disease and
other conditions
caused by the build - up
of fats, cholesterol, and
other substances on the artery walls, is supported by findings from two new studies from researchers in the Perelman School
of Medicine at the University
of Pennsylvania.
Collins and his colleagues exposed one culture
of Escherichia coli — some strains
of which colonize the human and animal gut;
others of which are notorious
for causing disease outbreaks — to increasing amounts
of an antibiotic over time.
University
of Adelaide researchers have developed a new theory
for the
causes of dementia and
other neurodegenerative
diseases, involving an out -
of - control immune system.
In 2013 Obama directed the U.S. Centers
for Disease Control and Prevention (CDC) and
other federal agencies to study the
causes and prevention
of gun violence.
But the U
of U Health investigation is the first to examine a large cohort
for viruses that
cause other tropical infectious
diseases.
We intend to follow up this work by trying to get yet more detail on the prevalence
of such mutations as well as by testing
for these events in
other tissues; most genetic investigations are performed only in blood, so we may have missed some
disease -
causing mutations by not testing elsewhere,» Dr Gilissen will conclude.
The more Duesberg looked
for answers, the more he came to believe that the original hypothesis
of top AIDS researchers was actually correct: The
disease was — at least in the United States — brought on by drug use and
other immune - suppressing
causes.
Certain conditions affect one sex more than the
other, he notes, so «if the genetics
of a cell affects the progress
of a
disease, it might suggest specific
causes or treatments
for disease.»
Mikovits,
for her part, took pains to tell members
of the lay press and
other scientists that the virus had not been proved to
cause CFS, merely that it was «associated» with the
disease.
If massive overgrowth
of clostridia is the
cause of enteritis necroticans, the
disease might be expected to occur in places
other than Papua New Guinea, and without the necessity
for ingesting a witches» brew quite so potent as the one cooked up during pig feasting.
But
for a host
of other risk factors — such as cigarette smoke and certain bacterial infections — the
disease -
causing mechanism is unclear.
For years, the fungus Ophidiomyces ophiodiicola was the suspected culprit behind the
disease, but scientists couldn't tell whether the pathogen was
causing the skin lesions they were seeing on dead snakes or if the fungus had just taken advantage
of lesions that were there from some
other cause.
Diabetes is the seventh leading
cause of death in the United States and a major risk factor
for other life - threatening conditions, including heart
disease and stroke.
«Our findings have broad implications not only
for malaria in pregnancy (125 million pregnancies at risk each year), but also
for other globally important
causes of adverse birth outcomes such as preeclampsia,» says Dr. Kain, who is also Science Director, Tropical
Disease Unit at the Toronto General Hospital, UHN.
«In the most recent global burden -
of -
disease study, diarrheal
disease accounts
for the loss
of more disability - adjusted life years than any
other infectious
disease, and cryptosporidiosis is the second leading
cause of diarrheal illness.»
This is true
for the origin
of arrhythmia and
other cardiac dysfunctions, which represent the second most common
cause of death in this
disease.
Defective genes can be
caused by mutations in either the maternally - inherited mitochondrial genome (mtDNA) or more frequently, the genes located on the autosomes, the 23 pairs
of chromosomes which are responsible
for all traits and all
other genetic
diseases.
For instance, a finding published by researchers at the Pennington Biomedical Research Center in Baton Rouge, Louisiana, in 2009 said that longer lengths
of sitting were directly proportional to an increased risk
of death from cardiovascular
disease and most
causes of death
other than cancer.
Part
of the problem is the lack
of resources we ourselves direct to food from abroad: The FDA has a minuscule team
of some 1,500 inspectors devoted to food imports, a workforce too small to screen more than a tiny fraction
of the food that arrives at U.S. ports each year
for microbial pathogens or
other disease -
causing contaminants.
But the study, conducted through the new USTAR Center
for Genetic Discovery at the U
of U, shows that Phevor's unique approach allows it to identify
disease -
causing genes more precisely than
other computational tools.
For more than 60 years, researchers have been hypothesising that the
diseases are
caused by, among
other factors, changes to the level
of the neurotransmitter.
But
for others, only 10 percent
of the mtDNA molecules with the variant are needed to
cause disease.
Such methods may in fact exacerbate bad breath by drying out the mouth and can allow species that
cause gum
disease and
other infection to take over by destroying large swathes
of native bacteria that are not responsible
for producing bad odors.
Culver adds that — like
other work on the
cause of cave fish blindness — the new research may also have implications
for human
disease.
For example, clumps
of proteins called amyloid fibrils are thought to be the
cause of Alzheimer's
disease as well as several
other devastating illnesses.
A new study in Proceedings
of the National Academy
of Sciences USA could turn this long - held notion on its ear, paving the way to new therapies
for Alzheimer's and
other diseases that
cause dementia and memory loss.
The finding is anticipated to help in the search
for causes of kidney
disease, new drug development, and
other cellular research.
But
other scientists have pointed to natural
causes, including volcanic eruptions,
disease, and climate change at the end
of last Ice Age, as the key reasons
for these species» demise.
«The alterations
caused by the long - term consumption
of sunflower and fish oils make the liver susceptible to non-alcoholic steatohepatitis, a very serious
disease that may act as a catalyst
for other liver
diseases such as cirrhosis and liver cancer,» Prof. Quiles notes.
Buoyed by these results, Dana - Farber researchers are working to create a derivative
of dBET1 that can be used as a drug in human patients — and to extend the conjugate strategy
for the treatment
of other cancers and
other genetically -
caused diseases.
«Cutting sodium can
cause other physiological changes such as increased resistance to insulin, which can set the stage
for diabetes and increase the risk
of death from heart
disease,» Stolarz - Skrzypek says.
LONDON — Wellcome Trust, the United Kingdom's largest biomedical research charity, today announced more than # 4 million in support
for a pioneering, and potentially controversial, IVF treatment that could prevent some forms
of muscular dystrophy and
other diseases caused by defective mitochondria, the energy - generating organelle in cells.
NASH, which
causes inflammation
of the liver that is not
caused by alcohol abuse, is a very serious condition and can act as a catalyst
for the onset
of other diseases such as cirrhosis and liver cancer.