Sentences with phrase «for particular cell types»

In each case there is interest in obtaining comprehensive, accurate data for particular cell types and in identifying patterns of variation within the data.

Not exact matches

«The problem with plasma cell - free liquid biopsy in particular is that the amount of wild - type [DNA] can be very, very high, and so keeping that really rare signal from being swamped out by the wild - type... is key,» says Dawne Shelton, R&D manager for in vitro diagnostic products at Bio-Rad in Hercules, California.

«A personalised immunotherapy was prepared for each patient by taking a sample of their blood and extracting a particular type of immune cell called dendritic cells.

Scientists are hopeful that ultimately these cells could be transformed in the laboratory to yield specific cell types needed for a particular treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.

The company's goal is to create a comprehensive source of stem cells that could be of particular use for treating people of Middle Eastern descent, whose tissue types are often underrepresented in the public tissue banks such as those in the U.S. and elsewhere.

While the genetic code carried in our DNA provides instructions for cells to manufacture specific proteins, it is a second code that determines which genes are in fact activated in particular cell types.

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in the liver.

Cancer stem cells, a type of self - renewing cell found in tumors, are of particular interest because they are the main cell type responsible for tumor progression and for resistance to chemotherapy and radiotherapy, and therefore a major cause of tumor recurrence after treatment.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

Yet in other cases, a missing cell type is responsible for causing a particular disease.

Narrowing the treatment to a particular tumor cell type makes for a more effective — and less harmful — oncolytic approach.

In lymph nodes, a particular type of stromal cells that forms a scaffold for lymphocytes to crawl around within the node normally secretes an enzyme called autotaxin, which is responsible for the production of the lipid signaling molecule, lysophosphatidic acid (LPA).

He adds, «This study was actually a pilot project for a much larger effort within the Center for Molecular Therapeutics to map responses against drug combinations across hundreds of cancer cell lines, not just melanoma, and look for novel combinations that will benefit subsets of patients regardless of the particular type of tumor they have.

These latter two cell types can mount effective immune responses to viruses and tumors; whereas, exhausted T cells fail and memory T cells, in particular, for long - lasting durable effects.

The research provides more evidence for how these lncRNAs, which were once thought to be a type of «junk DNA» of no particular value or function, may instead play a critical role in triggering cells to become malignant and spread.

In research published this week in the Journal of Neuroscience, University at Buffalo scientists and colleagues focused on a particular protein, called a transcription factor, that regulates gene activity necessary for the development of one type of retinal neuron, the horizontal cells.

For example, one thing that we are doing is to try to differentiate individual pluripotent stem cells into a particular cell type with a shotgun approach.

The Hippocampal Formation contains several types of cells which code for different aspects of space: the animal's current location within the environment, its heading direction, the distance over which it travels in a particular direction, and the location of environmental boundaries.

In particular, they are now looking for expertise in molecular biology, especially in virus - based techniques for introducing new genes into specific cell types in the grid - cell circuit.

In one of the experiments, for example, activation of a particular signal at the correct time elicits the appearance of the mesoderm, endoderm and ectoderm — the precursors of all cell types — with a spatial organization similar to that of an embryo.

Depending on the composition of the viral envelope, viruses exhibit particular patterns of cell tropism, and thus are suited for infecting specific cell types.

Certain small molecules in particular have affinity for particular types of cells.

The study relates to a particular type of vaccine (killed) against a particular virus, influenza, though the findings might hold true for other killed vaccines and for those vaccines consisting only of proteins produced by GM in bacteria, yeast or insect cells, against diseases such as hepatitis B (HBV) and human papilloma virus (HPV, the causative agent of cervical cancer).

«As we better understand the underlying genetic circuitry that orchestrates development of a particular kind of stem cell into a specialized cell type, we should be able to manipulate it for such purposes.»

«There is a lot of excitement in stem cell biology these days about the possibility of rationally and efficiently generating particular cell types from different stem cells for therapeutic purposes,» he said.

«Two decades of discoveries in the fields of stem cell biology, cortical brain development, and cell transplantation have revealed the potential for particular types of neurons to repair the nervous system, representing a possible breakthrough therapy for patients with devastating neurological diseases,» said Cory Nicholas, Co-Founder, VP of Research at Neurona.

To overcome these hurdles, Bhatia and her team reprogrammed human skin cells into induced pluripotent stem cells (iPSCs)-- embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease.

Nor is it shocking that, having found a way to save Quinn, the writers quickly come up with a means for his rescue, this time by way of a fancy algorithm that Carrie (Claire Danes) and Astrid (Nina Hoss) are able to run off the little information they have about Quinn's captor, Bibi (Rene Ifrah), and the particular type of mosaic tiling on the floor outside Peter's cell.

It replicates in a particular type of cell called a T - lymphocyte, which is responsible for regulating the immune system.

There is also a particular need for replication and extension of our finding that greater protective parenting was associated with a significant shift in cell - type composition in the direction of relatively fewer CD14 monocytes (a marker of innate immunity), suggesting potential long - term impact on chronic inflammation (Irwin and Cole, 2011).