Sentences with phrase «for prcd»

If your dog is a Labrador Retriever, Chesapeake Bay Retriever or Portuguese Water Dog and is well beyond the normal age of onset for prcd - PRA (about six years), you are confident that it is showing no signs of vision loss, and you have reliable clinical exam information with no signs of vision loss, you don't need an ERG.

Yes, all Cocker Spaniels can be tested for prcd - PRA.

As announced June 1, 2005, OptiGen now provides a direct mutation test for prcd - PRA.

Indeed, the best thing about the test for prcd - PRA is that it helps keep the gene pool from shrinking.

The result — discovery of the cause for prcd - PRA in PWDs AND improvement of the test.

Fortunately, Drs. Gustavo Aguirre and Gregory Acland at the James A. Baker Institute at Cornell University have localized the gene for prcd in some breeds of dogs to chromosome 9.

They have identified genetic markers for the prcd PRA in Labrador Retrievers, Golden Retrievers and a number of other breeds.

Since the test for prcd - PRA can only reveal the existence of affected or carrier status of this one form of PRA, breeders and owners of the breed should still have regular eye exams by veterinary ophthalmologists.

Fortunately the majority of their mates were Normal for prcd and so relatively few Affected offspring have been produced.

If this is accurate, they are not false negative for prcd.

These conditions are not detectable with OptiGen's test for prcd - PRA.

Genetic Registries — ACDs: According to the policy of the ACDCA, the Orthopedic Foundation for Animals (OFA) will serve as database administrator for the Australian Cattle Dog Health Registry, including the database for prcd - PRA results.

To date, OptiGen has tested hundreds of golden retrievers from multiple lines and countries for prcd - PRA and so we can now provide more extensive information on the incidence of the disease in this breed.

Given the multiple forms of PRA, if an Aussie is diagnosed with the disease it would be wise to confirm the diagnosis by having it tested for prcd (which Optigen, the lab offering the test, will do for no charge.)

DNA tests are available for several diseases that affect Golden Retrievers (such as for prcd - PRA, GR - PRA1, and ichthyosis), and more will certainly be added over time.

Nov. 27, 2006 — News Release — GENETIC TEST FOR prcd - PRA ANNOUNCED FOR Spanish Water Dog and Australian Shepherds — Ithaca, New York, USA.

The number of Spanish Water Dog and Australian Shepherds samples that have been tested for prcd is low and at this point it is not possible to determine the prevalence of the disease within the breed.

For any Spanish Water Dog and Australian Shepherds that does not have a diagnosis of PRA, OptiGen will accept samples for prcd - PRA testing at the fee schedule viewable on the website.

It's been proven that all breeds being tested for prcd - PRA have the same disease caused by the same mutated gene.

June 1, 2005 New Mutation Test for prcd PRA Is Now Available OptiGen, LLC, proudly announces identification of the gene causing canine prcd - PRA (progressive rod - cone degeneration form of Progressive Retinal Atrophy).

The Labrador Retriever Club support the use of OFA Data Bases, Penn Hip, CERF and other individual tests such as the test for CNM1, the Optigen tests for the prcd form of PRA in the Labrador Retriever, and the new test for EIC.

Optigen today announced that the linkage test for the prcd form of PRA will soon be available in two additional breeds, English Cocker Spaniels, and Chesapeake Bay Retrievers.

They will screen the dog not only for prcd but the other types of PRA for which there are DNA tests as well.

ALL OF MY BREEDING DOGS ARE TESTED FOR PRCD - PRA (Progressive Retinal Atrophy) which causes blindness in poodles thru OPTIGEN in Ithaca, New York.

Not exact matches

Based on the settlement, Paw Print Genetics now holds the exclusive North American sublicense from OptiGen for PRA - prcd, CEA, CSNB and RD / OSD testing in the U.S. and Canada.

The patents at issue in the case are owned by Cornell University and are licensed to OptiGen for canine genetic testing related to progressive retinal atrophy (PRA - prcd), Collie eye anomaly (CEA), congenital stationary night blindness (CSNB), and Retinal dysplasia / Oculoskeletal dysplasia (RD / OSD).

Because there is more than one form of PRA, if there should happen to be a second form in the breed and your dog had the genes for that type it would be possible to test your dog «for PRA» using the PRCD test with clear results when the dog is actually affected — but with a different form of PRA.

These «clear» dogs can be bred to any mate - even to a prcd - affected dog which may be a desirable breeding prospect for other reasons.

The only one of these tests that should be used for Aussies is the one for Progressive Rod Cone Degeneration (PRCD).

prcd stands for progressive rod - cone degeneration which is a type of PRA known in several breeds.

The OptiGen test for PRA in the Spanish Water Dog and Australian Shepherds identifies a mutation in the prcd gene that was discovered through extensive research in the laboratories of Dr. Gustavo Aguirre and Dr. Gregory Acland at Cornell University (Zangerl et al., Genomics 88, 551 - 563, 2006).

As an individual breeder, if you are considering importing a dog you should only do so if it has had its hips and elbows cleared, has had a clear eye exam within the past year, a thyroid panel, Pelger - Huet Anomaly screen, and has been DNA tested for MDR1, cataracts, CEA, the PRCD form of PRA, degenerative myelopathy, and cobalamin malabsorbtion.

With the other genetic tests currently available for Australian Shepherds, most notably MDR1, CEA and PRA, the answer to the «what to do» question is straightforward: Having a single copy of the CEA - CH or prcd / PRA mutations or even two of the MDR1 are not reasons to remove a dog from your breeding program.

PRA of any type is rare in Aussies, but most of those who do have it have the progressive rod - cone degeneration (prcd) form, which is what people typically test for.

If a dog with a PRA diagnosis does not have prcd, Optigen will also screen the sample to see if it might have one of the other forms for which they have a test.

Mutation frequency for Collie Eye Anomaly (CEA) and Progressive Rod Cone Degeneration (PRCD, a form of PRA) in the breed is much lower.

For example, the prcd - PRA DNA test detects one specific mutation in the prcd gene and the XL - PRA test detects a specific mutation in a different gene.

The PRA test for the Labrador (prcd - PRA) is different than the PRA test for the Samoyed (XL - PRA).

Multiple Tests for Labrador retrievers or Samoyeds not tested previously by OptiGen: There is a discounted price for ordering multiple tests on one sample (e.g. prcd - PRA and RD / OSD, or XL - PRA and RD / OSD).

Intriguingly, an identical homozygous mutation was identified in a human patient with recessive retinitis pigmentosa, the human equivalent of PRA, and established the novel retinal gene, PRCD, as an important gene for the maintenance of rod photoreceptor structure and function across species.

The same ancestral autosomal recessive mutation for the progressive rod cone degeneration (prcd) form of progressive retinal atrophy (PRA) is found in the American Cocker Spaniel, American Eskimo Dog, Australian Cattle Dog, Australian Shepherd, Chesapeake Bay Retriever, Chinese Crested Dog, English Cocker Spaniel, Entelbucher Mountain Dog, Finnish Lapphund, Golden Retriever, Kuvasz, Labrador Retriever, Lapponian Herder, Norwegian Elkhound, Nova Scotia Duck Trolling Retriever, Poodle, Portuguese Water Dog, Silky Terrier, Spanish Water Dog, Stumpy Tail Cattle Dog Swedish Lapphund, and Yorkshire Terrier.3 This list continues to grow as more breeds are discovered with the same defective gene.

The OptiGen prcd test for Entlebucher Mountain Dogs provides almost 100 % identification of these dogs.

OptiGen holds an exclusive international license from Cornell University for the testing of prcd - PRA.

The OptiGen prcd test for American Eskimo Dogs provides almost 100 % identification of these dogs.

Rather, they are «positive» for another disorder and do not have prcd - PRA.

This situation is very different than for the initial prcd - PRA test in other breeds where the rate of false positives was substantial.

This has been true for the two prcd - PRA affected golden retrievers that we have received at OptiGen that are of diagnostic age.

Two dogs out of 250 research dogs did not show as «affected» using the prcd - PRA mutation test for ACDs, even though they appeared to have PRA upon exam by Dr. Acland.

The response by golden retriever owners and breeders to the knowledge that prcd - PRA occurs in their breed has been exemplary of what any conscientious breed club would hope for.

These «clear» dogs can be bred to any mate - even to a prcd - affected dog that may be a desirable breeding prospect for other reasons.