Targeted treatment up front improves survival for advanced prostate cancer, and we predict a change in thinking
for precision cancer medicine.
While determining the genetic makeup of a patient's tumor is a critical tool
for precision cancer medicine, the report's authors noted several challenges and unanswered questions about large - scale clinical application of the methods.
If these results are validated in subsequent testing, in the future an oncologist will have many more options
for precision cancer therapy.»
Not exact matches
Syapse is on a mission to deliver the best care
for every
cancer patient through
precision medicine.
«Such advances in sequencing technology facilitate rational
precision therapies
for individuals with late - stage
cancer.»
In 2004 the
precision strategy got a boost with two FDA approvals
for pharmaceuticals to treat colon
cancer — the second most common cause of U.S.
cancer deaths.
Little progress has been made in outcomes
for pancreatic
cancer patients over the last 40 years, and we believe that
PRECISION Panc will reshape how we approach treatment development.
«Without
Cancer Research UK and their vision for cancer precision medicine, and the commitment of the other stakeholders, we couldn't get PRECISION Panc up and running.&
Cancer Research UK and their vision
for cancer precision medicine, and the commitment of the other stakeholders, we couldn't get PRECISION Panc up and running.&
cancer precision medicine, and the commitment of the other stakeholders, we couldn't get PRECISION Panc up and runnin
precision medicine, and the commitment of the other stakeholders, we couldn't get
PRECISION Panc up and runnin
PRECISION Panc up and running.»
«New era in
precision medicine
for pancreatic
cancer.»
The investment will support the
PRECISION Panc project which aims to develop personalised treatments
for pancreatic
cancer patients, improving the options and outcomes
for a disease where survival rates have remained stubbornly low.
Professor Johann de Bono, Regius Professor of
Cancer Research at The Institute of Cancer Research, London, and Consultant Medical Oncologist at The Royal Marsden NHS Foundation Trust, said, «Our study identifies, for the first time, genetic changes that allow prostate cancer cells to become resistant to the precision medicine ola
Cancer Research at The Institute of
Cancer Research, London, and Consultant Medical Oncologist at The Royal Marsden NHS Foundation Trust, said, «Our study identifies, for the first time, genetic changes that allow prostate cancer cells to become resistant to the precision medicine ola
Cancer Research, London, and Consultant Medical Oncologist at The Royal Marsden NHS Foundation Trust, said, «Our study identifies,
for the first time, genetic changes that allow prostate
cancer cells to become resistant to the precision medicine ola
cancer cells to become resistant to the
precision medicine olaparib.
The researchers, at The Institute of
Cancer Research, London, and The Royal Marsden NHS Foundation Trust, say their test is the first developed for a precision prostate cancer therapy targeted at specific genetic faults within tu
Cancer Research, London, and The Royal Marsden NHS Foundation Trust, say their test is the first developed
for a
precision prostate
cancer therapy targeted at specific genetic faults within tu
cancer therapy targeted at specific genetic faults within tumours.
Study co-leader Wyndham Wilson, M.D., Ph.D., NCI Center
for Cancer Research, added, «This is the first clinical study to demonstrate the importance of
precision medicine in lymphomas.»
«New three - in - one blood test opens door to
precision medicine
for prostate
cancer: Test picks out men
for treatment, detects early signs of resistance and monitors
cancer's evolution over time.»
«However, there is still much more to understand before the potentially huge benefits of widespread
precision treatment
for prostate
cancer will reach men in clinics across the UK.
In the era of
precision medicine, targeting the mutations driving
cancer growth, rather than the tumor site itself, continues to be a successful approach
for some patients.
«We have found another piece in the
cancer puzzle — knowledge that could one day be used
for more
precision in screening and breast
cancer prevention, and also help with therapeutic approaches to block some of the earliest alterations before
cancer develops and starts to spread.»
The findings support a
precision approach to treating pancreatic
cancer, the fourth most deadly
cancer for both men and women.
«Researchers ID
cancer gene - drug combinations ripe
for precision medicine: Yeast, human cells and bioinformatics help develop one - two punch approach to personalized
cancer therapy.»
This discovery could potentially be another avenue
for precision medicine, which would allow
cancer treatment to be tailored to the patient's DNA.
The process, which located a genetic site
for the most common form of prostate
cancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer C
cancer, has potential
for developing
precision therapy
for other
cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson
Cancer C
Cancer Center.
Augmenting and regulating telomerase function will have to be performed with
precision, walking a narrow line between cell rejuvenation and a heightened risk
for cancer development.
The new findings could be used to inform
precision - medicine approaches that help minimize a person's risk
for common diseases — such as diabetes, cardiovascular disease and
cancer — by tailoring diet - based prevention and therapy to the specific needs of an individual.
In an era of
precision medicine, the guideline provides recommendations
for pathologists, oncologists, and other
cancer health professionals on the current state - of - the - art recommendations
for the molecular testing of lung
cancer.
Professor Tim Maughan, Clinical Director of the
Cancer Research UK / Medical Research Council Oxford Institute
for Radiation Oncology, said «This novel and exciting finding provides a new scientific basis
for precision targeting of some
cancers which are currently very difficult to treat, and we are now taking these findings into clinical trials.»
A team of researchers at the Massachusetts General Hospital and Harvard Medical School in Boston has developed technologies
for precision measurement of cell migration speed before and applied the new tool to study the variations of migration speed in population of
cancer cells.
The findings are being presented as part of a poster presentation by members of the Rutgers
Cancer Institute
precision medicine team at the Annual Meeting of the American Association
for Cancer Research (AACR) which begins this weekend in New Orleans.
This new knowledge is also making
precision medicine a reality by enabling the development of highly targeted therapies that offer the potential
for improved treatment outcomes, especially
for patients battling
cancer.
Other biomarkers and genetic signatures are being used in an effort to predict the aggressiveness of an individual patient's prostate
cancer, «but the current information doesn't make it possible
for their gene signature to be an actual target
for precision medicine targeted therapy,» Ellis explained.
MacConaill noted that the results of Profile genomic testing are being used to further research within the institutions and are being shared more widely with initiatives like Project GENIE of the American Association
for Cancer Research (AACR), which will help advance the field of
precision medicine.
This new commitment to the
precision medicine initiative will provide additional opportunities over the next three years
for physicians to analyze the genomic profiles of pediatric patients to better understand their
cancers and help improve treatment options.
«In identifying a specific abnormality in a patient's
cancer instead of the overall organ where it first presented, the opportunity exists to provide tailored therapies for patients,» notes Lorna Rodriguez, MD, PhD, director of the precision medicine initiative at the Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical S
cancer instead of the overall organ where it first presented, the opportunity exists to provide tailored therapies
for patients,» notes Lorna Rodriguez, MD, PhD, director of the
precision medicine initiative at the
Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical S
Cancer Institute and professor of obstetrics, gynecology and reproductive sciences at Robert Wood Johnson Medical School.
Recognizing a need to further explore genomic profiling in pediatric malignancies, the Hugs
for Brady Foundation has committed $ 300,000 to the
precision medicine initiative at Rutgers
Cancer Institute of New Jersey.
Berkeley researchers isolated circulating tumor cells from the blood of breast
cancer patients, then used microscale physics to design a
precision test
for protein biomarkers, which are indicators of
cancer.
The Oncology Research Information Exchange Network, or ORIEN, is the world's largest
precision collaboration
for cancer research, one that will enable researchers and clinicians to share data to accelerate the development of
precision medicine treatments.
Dr. Mody is leading a clinical trial investigating the role of next generation sequencing (NGS) in
precision oncology
for developing novel biomarkers and therapeutic targets against refractory childhood
cancers.
I use
precision medicine to create better treatment options
for all women who have ovarian
cancer.
In effect, Affigen uses
cancer's «Achille's Heel»: the proteins which distinguish tumor cells from normal cells, that can target tumor cells
for destruction with extreme sensitivity and
precision.
Dr. Andrew Hsieh of the Human Biology Division is teaming up with colleagues at Fred Hutch and Memorial Sloan Kettering
Cancer Center to make progress toward precision medicine for patients with prostate c
Cancer Center to make progress toward
precision medicine
for patients with prostate
cancercancer.
On Dec. 1 - 2, those issues will come to the fore as national experts in genetics, medicine, law, big data and other fields gather
for Frontiers in
Precision Medicine II:
Cancer, Big Data and the Public, a unique
precision medicine symposium at the University of Utah S.J. Quinney College of Law, Center
for Law and Biomedical Sciences, University of Utah Health Sciences, Huntsman
Cancer Institute, and University of Utah Center
for Excellence in ELSI Research (UCEER) addresses those topics as
precision medicine is gaining more attention nationwide from health care systems, practitioners, researchers, insurers and federal agencies.
What was once dismissed as futuristic has now become reality
for some
cancer patients, and with leading - edge research and groundbreaking partnerships, City of Hope stands in the
precision medicine vanguard.
A new multicenter trial focuses on providing
precision treatments
for rare
cancers based on genetics, not tumor site.
For almost three decades, Dr. Maharaj has been treating patients with blood cancers and immune disorders in a totally outpatient basis, leading the field for a personalized and precision - based approach to disea
For almost three decades, Dr. Maharaj has been treating patients with blood
cancers and immune disorders in a totally outpatient basis, leading the field
for a personalized and precision - based approach to disea
for a personalized and
precision - based approach to disease.
Two new
precision medicine tests that look beyond
cancer genes to identify novel therapeutic targets have just received New York State Department of Health approval and are now available to both oncologists and
cancer researchers
for use at the front lines of patient care.
The tests are based on research conducted by Columbia University Irving Medical Center (CUIMC) investigators — and could pave the way
for a more precise approach to
cancer therapy and help find effective drugs when conventional approaches to
precision medicine have failed.
In addition, U-M is internationally renowned
for leadership in
precision oncology, using genetic sequencing to effectively target and treat
cancer at an individualized level.
Many scientists now believe that — complementing its initial focus on mutated genes —
precision oncology must now also address the activity of otherwise normal proteins and molecular pathways that are ultimately responsible
for cancer cells» malignant behavior.
Current
precision medicine approaches aim to disable those mutated genes, and many
cancer patients today have their tumors analyzed
for mutated genes that can be treated with available targeted therapies.
The difference in expression patterns of individual
cancers observed in the study strongly reinforces the need
for personalized
cancer treatment based on
precision medicine.
Atul Butte, PhD, who is Priscilla Chan and Mark Zuckerberg Distinguished Professor at UCSF and directs the Institute
for Computational Health Sciences, a hub
for precision medicine research on campus, echoed the excitement felt across UCSF about moving towards clinical application of
precision medicine: «
Precision medicine is not just a «nice idea» at UCSF — it is benefitting real people, from
cancer patients with unusual tumor mutations to children with undiagnosed genetic diseases.