The Institute's phenotyping platforms are adapted for the study of mutant mice and genetic reference populations but can also be
used for preclinical studies including the validation of therapeutic targets as well as pharmacological and toxicological studies in the mouse.
«Because mouse models are
indispensable for preclinical studies, the resource now made available shall contribute to a better understanding of microbe - host interactions and to a higher degree of standardization,» said Clavel.
Small - animal imaging has become an important research
tool for preclinical studies of infectious diseases, according to senior author Thomas M. Bocan, Ph.D., of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).
«The
model for preclinical studies to predict with great accuracy which drugs would work in the clinic was developed a decade ago,» says Dr. Chesi.
Sponsored by: Houston PetTalk, Texas Veterinary Cancer Registry, Amegy Bank, The University of Texas MD Anderson Cancer Center, Texas A&M
Institue for Preclinical Studies & Doody Calls.
The Pilot Bioproduction Facility headed by Dr. Kenneth H. Eckels, produced small batches of vaccine candidates that were
used for the preclinical studies and is currently manufacturing a vaccine lot for use in initial human clinical studies.
The Texas A&M
Institute for Preclinical Studies (TIPS) provides large animal Good Laboratory Practices (GLP) and translational research studies with unique access to expertise in all major medical and scientific disciplines including surgery, biomedical engineering, advanced imaging, pathology, radiography, interventional cardiology, neurology, animal behavior, chemistry, and engineering.
The phenotyping platforms of PHENOMIN - ICS area, adapted to study genetically modified mouse models, can also be used
for preclinical studies, including the validation of therapeutic targets, as well as pharmaceutical and toxicological studies in mice.