Using the new science of optogenetics, scientists can activate or shut down neural pathways, altering behavior and heralding a true
cure for psychiatric disease.
Govoni says that when patients are
treated for psychiatric disease, the creative impulses often associated with bipolar disorder, dementia, or even depression may fall by the wayside.
«Many pharmaceutical companies largely abandoned drug
development for psychiatric diseases decades ago because the conditions are considered too difficult to treat, said Steven Hyman, director of the Stanley Center for Psychiatric Research at the Broad Institute.
It is perhaps thus likely that that these damaged genes
coding for psychiatric diseases are overrepresented in women with fertility problems, and, if transferred to their offspring, this may at least partly explain the increased risk of psychiatric diseases.»
The new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000 human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk
factor for psychiatric disease by interfering with the way the brain regulates connections between neurons.
It is important to understanding how these component parts interact with each other in order to devise treatment
strategies for psychiatric diseases such as addiction, Tourette's syndrome and obsessive - compulsive disorder,» concludes Dr. Britt.
â $ œFew biological markers have been available for PTSD or
for psychiatric diseases in general, â $ says first author Kerry Ressler, MD, PhD, associate professor of psychiatry and behavioral sciences at Emory University School of Medicine and a researcher at Yerkes National Primate Research Center.