Sentences with phrase «for reactive oxygen»

We describe Eros (essential for reactive oxygen species), a protein encoded by the previously undefined mouse gene bc017643 , and show that it is essential for host defense via the phagocyte NAPDH oxidase.

I've been experimenting with T10 dextran coated iron oxide nanoparticles, obviously not the same as fullerenes, but still a very interesting tool, I've been testing if the coating is giving the particle antioxidant abilities because of it's the (basically) indigestable sugar chains (glucose) creating a high surface area which are largely made from hydroxyl groups, I hypothesised this act's as a «sink» for reactive oxygen species converting them to water.

The researchers don't yet know the exact chemical reactions that produce the free radicals, but the work «quite solidly establishes a new role for reactive oxygen in development,» says ageing researcher Karl - Heinz Krause of the University of Geneva in Switzerland.

Not exact matches

Finally, while the underlying mechanism is unclear, the team found that having reduced NOX2 - derived reactive oxygen species also raised the risk for these autoimmune diseases.

For decades, researchers have known that reactive oxygen species, or free radicals, can do serious damage to cells and trigger cancer.

This fact makes vacuum UV light extremely useful for industrial applications from sterilizing medical devices to cleaning semiconductor substrates because when it strikes oxygen - containing molecules on a surface, it generates highly reactive oxygen radicals, which can completely destroy any microbes contaminating that surface.

«Without a membrane, the photoanode and photocathode are close enough to each other to conduct electricity, and if you also have bubbles of highly reactive hydrogen and oxygen gases being produced in the same place at the same time, that is a recipe for disaster,» Lewis says.

Geologist Martin Kennedy and his colleagues from the University of California, Riverside realized that clay minerals in marine sediments are responsible for trapping the organic carbon that would otherwise bond with highly reactive oxygen.

Sep. 14, 2017 — Blocking acid reflux - induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

Intracellular reactive oxygen species (ROS) levels were measured for all groups as described earlier [22].

«Without a membrane, the photoanode and photocathode are close enough to each other to conduct electricity, and if you also have bubbles of highly reactive hydrogen and oxygen gases being produced in the same place at the same time, that is a recipe for disaster,» Lewis says regarding his findings published in PNAS.

This required the development of strict protocols for exposure and handling due to the relatively reactive nature of the alloys to hydrogen - or oxygen - rich environments.

Furthermore, the manganoporphyrin was stably contained within the microcapsule without release, and researchers showed that both manganoporphyrin and tannic acid were required for the synergistic scavenging of reactive oxygen species.

At Emory, Kathy Griendling's group is well known for studying NADPH oxidases (also known as Nox), enzymes which generate reactive oxygen species.

Although many years ago we found that reactive oxygen species (ROS) are required for full expression of hippocampal LTP and memory, it is clear that the aged and diseased brain handle ROS much differently as many studies have pointed to a role for excessive ROS and oxidative stress in age - related cognitive decline and impaired memory associated with Alzheimer's disease (AD).

Research had shown that increased mitochondrial activity may be at least partly responsible for extending the life span of yeast, roundworms, fruit flies and some mammals — perhaps by reducing the production of disease - causing reactive oxygen species (ROS).

For this reason, it is very anti-inflammatory and can reduce reactive oxygen species by increasing oxygen levels.

Chronic oxidative stress — meaning chronic presence of overly reactive oxygen - containing molecules and cumulative damage to tissue by these molecules — is a risk factor for the development of most cancer types.

More than one hundred vitamin B6 - dependent enzymes have been identified, mostly involved in amino acid metabolism: for oxygen transport via hemoglobin synthesis; in blood sugar regulation via conversion of stored carbohydrate to energy; in the development of the myelin sheath surrounding nerve cells; in the conversion of alphalinoleic acid to the essential long - chain fatty acid DHA; 28 and in the synthesis of neurotransmitters, phospholipids and sphingolipids, the vitamin niacin from tryptophan, and other vital metabolites.5 In addition to its role in enzyme reactions, B6 appears to moderate the action of some steroid hormones such as the glucocorticoid hormones, which in turn influence the metabolism of protein, carbohydrate and lipids.5, 9 B6 also is a potent antioxidant, rivaling carotenoids and vitamin E in its ability to quench reactive oxidants in the body.29

Free radicals are often used in the same sentence with cancer, oxidative stress is a favorite buzzword for many nutritional supplement companies, and reactive oxygen species are rarely mentioned because they're hard to pronounce.

The immune defense against these infections is glucose - dependent (as it relies on production of reactive oxygen species using glucose) and thyroid hormone - dependent (as thyroid hormone drives not only glucose availability, but also the availability of iodine for the myeloperoxidase pathway).

They claimed that witch hazel had a high affinity for human cells and cell membranes and hence was highly equipped to defend them against reactive oxygen species (free radicals).

Various hypotheses have been put forward to explain the molecular reasons for aging, a prominent role among them being played by the free radical theory of aging.3, 4 Free radical components (reactive oxygen species or ROS) or lipid peroxide (LPO) is involved in the pathogenesis and progression of accelerated skin aging and chronic skin conditions such as acne vulgaris.

As a general rule, the shorter the carbon chain, the more efficiently the MCT will be turned into ketones, which are an excellent source of energy for your body — far preferable to glucose, as ketones produce far less reactive oxygen species (ROS) when they are metabolized to produce ATP.

Chronic oxidative stress — meaning chronic presence over overly reactive oxygen - containing molecules and cumulative damage to our cells by these molecules — is a risk factor for development of most cancer types.

We all know how important regular exercise is for our physical, mental and emotional health, but strenuous anaerobic exercises have been reported to enhance the generation of reactive oxygen species (ROS); which in turn can contribute to both the initiation and progression of muscle fibre injury as well as impaired muscle performance.4 Green Tea Extract (GTE) however has been clinically proven to prevent oxidative stress induced by high - intensity training and subsequent muscle breakdown — once again thanks to its EGCG content.5

It has been known for quite some time that intense exercise increases the production of potentially toxic reactive oxygen species (ROS), which have been linked to aging and most chronic diseases, one way or another.

When your body is able to burn fat for fuel, your liver creates water - soluble fats called ketones that burn far more efficiently than carbs, thereby creating fewer reactive oxygen species (ROS) and secondary free radicals.

It's so important for tackling all manner of reactive oxygen species that having low levels means that other antioxidants will have to pick up the slack.

The mitochondria in our cells are responsible for releasing energy from the molecules in our food, but they also unleash electron - stealing free radicals like reactive oxygen and reactive nitrogen species.

For example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the production of reactive oxygen species in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseasFor example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the production of reactive oxygen species in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseasfor example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseases.

Glycoproteins and polysaccharide molecules like glycosaminoglycans are important structural components of the body; certain cell types rely on glucose for energy; and the immune system relies on glucose for generation of reactive oxygen species to kill pathogens.

Reactive oxygen species are signaling molecules for skeletal muscle adaptation.

See Curry post on «Nonequilibrium thermodynamics and maximum entropy production in the Earth system» paper by Axel Kleidon (downloadable) https://judithcurry.com/2012/01/10/nonequilibrium-thermodynamics-and-maximum-entropy-production-in-the-earth-system/ «The Earth system is maintained in a unique state far from thermodynamic equilibrium, as, for instance, reflected in the high concentration of reactive oxygen in the atmosphere.

Main Outcome Measures At age 32 years, study members were assessed for the presence of 3 age - related - disease risks: major depression, high inflammation levels (high - sensitivity C - reactive protein level > 3 mg / L), and the clustering of metabolic risk biomarkers (overweight, high blood pressure, high total cholesterol, low high - density lipoprotein cholesterol, high glycated hemoglobin, and low maximum oxygen consumption levels.