Not exact matches
This analysis suggests that a rare subset of tumor cells harbor different genetic alterations and that those cells serve as the seeds
for the recurrence of
rhabdomyosarcoma.»
«Overall, survival
for patients with recurrent
rhabdomyosarcoma is just 17 percent, and until now nothing was known about how tumors evolve in response to therapy,» said corresponding author Michael Dyer, Ph.D., a member of the St. Jude Department of Developmental Neurobiology and a Howard Hughes Medical Institute Investigator.
«A so - called «muscle» cancer is not really a muscle cancer: Pinpointing the cell type that turns malignant in
rhabdomyosarcoma opens the path
for better treatments.»
The unexpected discovery that
rhabdomyosarcoma is not really a muscle cancer may offer broader lessons
for researchers seeking the cellular origin of cancers.
All seven institutions used IGRT
for treatment of ependymoma (cancer of the tissue of the brain or spinal cord), abdominal and pelvic sarcoma, and
rhabdomyosarcoma (cancer of the muscles attached to the bones).
Pax3: Fkhr interferes with embryonic Pax3 and Pax7 function: implications
for alveolar
rhabdomyosarcoma cell of origin.
At the Solid Tumor Oncology Program, part of C.S. Mott Children's Hospital at the University of Michigan, we provide comprehensive, multidisciplinary care
for children with
rhabdomyosarcoma.
In addition to research on
rhabdomyosarcoma, the Ignatius laboratory has also generated new syngeneic zebrafish models of aggressive Malignant Nerve Sheath Tumors and hemangiosarcomas
for which there are no effective treatments.