Sentences with phrase «for second messengers»

This has been used to create reporters for second messengers by using protein (domains) that undergo a conformational change upon binding of e.g. Ins (1,4,5,) P3, calcium or cAMP.

Not exact matches

This marks the second time in four years that the chemistry Nobel has been awarded to someone working with x-ray crystallography; in 2006 Roger Kornberg took the prize for detailing the structure of messenger RNA, which is the molecule that carries the information the ribosome uses to build proteins, such as insulin or hemoglobin.
Each such «second messenger» is a crucial guide for the cell, helping to determine how the cell responds to the organism's needs
The recent explosion of green fluorescent protein (GFP) based sensors of pH, halides, proteases, kinases, G proteins, and many second messengers (including Ca2 +, cAMP, cGMP, nitric oxide, and IP3) have provided important tools for the design of screening assays.
A new cell permeant IP3 antagonist offers a useful tool for exploring the second messenger pathway.
Here we show how second messengers relevant to the Gq signaling pathway can be detected in living cells using assays for DAG, PIP2, and Ca2 +.
Inositol is a sugar that can serve as a precursor for a membrane phospholipid (phosphatidylinositol), a second messenger in signal transduction, an osmolyte, or an energy source.
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