Sentences with phrase «for shorter sequences»

Next, I scaled my previous confidence limits for shorter sequences.
For this short sequence, it's important for you to focus on your breath and tune into your body.
Along the way you even get to occasionally jump into the boots of Ciri for short sequences.

Not exact matches

Says Roberts: «He quickly figured out that if Illumina was successful, it would need more than the world's supply of oligonucleotides» — the short snippets of nucleic acid that are designed to pair up with specific genetic sequences, and which are critical for DNA or RNA analysis.
The term premium is the extra compensations investors require for the risk of holding a long - term treasury bond versus a sequence of short - term treasury bills over the same period.
They each begin with a quote from Scripture which sets the theme of the station, the Sign of the Cross, the Our Father, a contemplation, a short prayer taken, for example, from the Divine Office or a sequence from the Mass, a Hail Mary and a Glory Be.
The children sit in a circle and learn short songs and verses to remember the sequence of steps for each stitch.
He identified a short stretch of its sequence that repeatedly coded for leucine, an amino acid.
The one - time front man for heavy metal band Black Sabbath has joined the likes of DNA co-discoverer James Watson and Harvard University professor Henry Louis Gates on the short roster of people to have their full genome sequenced and analyzed.
So Axel Visel of the Lawrence Berkeley National Laboratory in California focused on «enhancers»: short sequences of DNA — which are still sometimes called «junk» — that do not code for genes but can influence their activity.
These repeating sequences have been dubbed CRISPR (or Crispr), for Clustered Regularly Interspaced Short Palindromic Repeats.
Get to work The researchers and engineers behind Philae have had months to prepare for the lander's reawakening, and have been planning sequences of short commands that can be performed quickly without stressing its battery.
Conventional genetic screening looks for specific mutated sequences of DNA, but the Dutch test simply searches for proteins which are shorter than those produced by healthy genes.
(«Katharos» is Greek for «pure,» and «Seq» is short for sequencing.)
A microsatellite is a short, repetitious sequence of DNA — CACACACA, for instance — in which the number of repetitions can change from one generation to the next and often does.
A comprehensive DNA sequencing of pancreatic cancer cases revealed not only a plethora of damaged genes, but potential diagnostic biomarkers that could help identify those with longer or shorter survival, and provide opportunity for new therapeutic interventions.
Looking for a mechanism, researchers found remnants of genes from past infections, sandwiched between odd, repeated bacterial DNA sequences — the «clustered regularly interspaced short palindromic repeats» that give CRISPR its name.
MicroRNAs are short bits of nucleic acid — the material of DNA and RNA — that can bind to messenger RNAs that code for protein because they have a complementary sequence of A, U, C and G.
Cohen, whose background includes developing operating systems support for computer games, has developed a program called LEVER - short for Lineage Editing and Validation program - that can identify, tag and track live cells, capturing patterns of motion and cell division, using sequences of microscopic time - lapse images.
To test whether skin - associated bacteria could be tapped for forensic use, Fierer and his colleagues swabbed the fingertips of three people and their computer keyboards and then sequenced short stretches of the bacterial DNA.
The differences between coding versus noncoding trees were not solely due to shorter sequence length of the coding data, because the full coding data set (13.3 million bp for c123) produced a tree with fully supported (100 % BS) relationships that were incongruent with those fully supported in the intron (19.3 million bp), TENT (37.4 million bp without the third codon position), and WGT (322.1 million bp)(Figs. 2 and 5B, and table S3).
These differences are not merely due to shorter alignments of the exon and UCE sequences, because each accounted for ~ 25 % of the TENT data, similar in sequence length to the random 25 % subset of the TENT with introns (table S3) that produced a tree with a higher average BS and a topology closer to the full TENT (Fig. 5A and fig.
With no candidate targets, the team took an objective approach by applying a peptide phage library to MDSCs, which permitted mass screening for candidate peptides — short sequences of amino acids — that bind to the surface of the MDSCs.
Using the 58 eggs confiscated in the Folgosa case back in 2003, she and her team searched for short DNA sequences that coded for a piece of the ribosome, the cell's protein - producing factory.
More than 1.4 billion short DNA sequences were generated with the help of modern instruments for next - generation sequencing.
Cappuccio and colleagues inserted a short DNA sequence that coded for a loop of six glutamic acids — a type of amino acid — into C. vibrioides.
Then, at age 7, the children's short - term memory ¬ ¬ ¬ was tested, for example, by having them repeat a sequence of numbers.
The viral genome sequence also enabled an international group of researchers, including Fouchier and Drosten, to quickly devise diagnostic tests that look for short, characteristic stretches of the virus's RNA.
But for A. marginale, for instance, researchers have found more than 235 short, repeating DNA sequences.
Researchers have fully sequenced the virus, which they dubbed hCoV - EMC (short for human coronavirus - Erasmus Medical Center).
As reported on 30 August 2017 in Scientific Reports, a short DNA sequence in the Japanese morning glory DFR - B gene was selected as the target for the CRISPR / Cas9 system.
However, its large genome was too cumbersome for conventional whole - genome shotgun sequencing, which sequences short fragments of the genome and then stitches the results together.
Through a combination of single - molecule imaging and bulk biochemical experiments, the research team has shown that the genome - editing ability of Cas9 is made possible by the presence of short DNA sequences known as «PAM,» for protospacer adjacent motif.
Conventional shotgun sequencing methods can only be used for fairly short strands of DNA.
The short size of the locus was ideal for 454 sequencing, and because single - molecule reads are generated, the authors were able to identify haplotypes of somatic hypermutations carried by individual leukemic cells.
We refer interested readers to systematic comparisons of other aspects of the next - generation sequencing pipeline, for example comparisons of benchtop high - throughput sequencing technologies [56], short - read mappers [57], variant callers [58] and variant - calling pipelines as a whole [59, 60].
Next - gen sequencing is particularly useful for analyzing highly fragmented DNA, adds Eske Willerslev, a geneticist at the University of Copenhagen's Natural History Museum of Denmark, because it can capture the sequences of exceedingly short stretches of nucleotides.
Discovered in 1938 by geneticist Hermann J. Müller, telomeres (Greek for «end part») are essentially protective caps composed of short DNA sequences on the tips of chromosomes.
An open source computer program for ordering short DNA sequence reads into long DNA fragments with the aid of the barcodes is also provided.
We designed PhylOTU, the first computational tool for estimating the taxonomic composition of metagenomic samples from short, next - generation sequencing reads.
«In our research project on pediatric leukemia we plan to use Gemcode to define the exact chromosomal breakpoints of large scale chromosomal rearrangements and repetitive sequences that are typical for leukemic cells, but are difficult to characterize in short sequence reads,» said Professor Ann - Christine Syvänen, who leads the Molecular Medicine group.
Short DNA fragments are not able to reassemble repetitive elements in the genome — for these hard to assemble regions longer sequence read information is needed.
Among vertebrates, the fish model displays easy high density breeding (short generation time), favourable biological peculiarities (accessibility and transparency of the eggs, genome sequenced for both species used on the platform), original technological approaches (confocal and two - photon microscopy), as well as a wide accessibility to fully transparent larvae usable up to 5 days after fertilization.
Short guide RNA was targeted to the sequence corresponding to the CCHa2 peptide - coding region, resulting in the isolation of putative null alleles for CCHa2 (CCHa2CR - 1, CCHa2CR - 2, and CCHa2CR - 3)(Figs 5A and S5).
Both the modification and the restriction enzymes become activated on a short specific nucleotide sequence, the recognition sequence, which is the substrate for methylation.
The most noticeable editing events found in this study occurred in the short part of the miRNA sequence that is necessary for correct target binding.
Because K2 - 39b has a short orbital period, its existence makes it seem unlikely that tidal destruction is wholly responsible for the differences in planet populations around subgiant and main - sequence stars.
One of SciLifeLab's research groups is the first site in Europe to obtain the new Gemcode system for phasing short - read DNA sequencing data.
The students are employing that technology — which includes CRISPR (clustered regularly interspaced short palindromic repeats) systems, DNA microarrays, real - time polymerase chain reactions, RNA sequencing and western blotting — to study acute myeloid leukemia (AML), which affects both children and adults and comes with a high mortality rate for older patients.
During the pilot phase, the Project is analysing Illumina short - read sequence data on 2,512 samples from multiple locations in Africa and Asia, together with laboratory samples for benchmarking and methods development.
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