With Jan Stichel at Annette Beck - Sickinger's lab, Leipzig University, Germany and David Weaver, head of the high - throughput screening facilities at Vanderbilt University, I will be screening Vanderbilt's library of
small molecules for potential allosteric
modulators of the human Y4 receptor.
Once the Vanderbilt
small molecule library has been screened
for potential
modulators of the Y4 receptor, I will use the results to design efficient and accurate descriptors that can be used with artificial neural networks to predict activity at the Y4 receptor based on a
small molecule's structural properties.