Two studies investigating the use of cannabis
for spasticity and three case report on use for neuropathic pain, post-traumatic stress disorder or Tourette syndrome all lacked controls or blinding, conferring a high risk of biased findings.
Not exact matches
Pediatric rehabilitation,
spasticity / tone evaluation and treatment, long - term care of chronically impaired children, transition of disabled children to adult services, muscular dystrophy, cerebral palsy, orthotics
for gait disorders, pediatric orthotics
Our aim is to raise # 70,000
for Tree of Hope to Seb to have life - changing SDR surgery which will remove or reduce the
spasticity in his legs so that he can move more freely.
Sativex, a cannabis - derived mouth spray, was licensed in the UK in 2010 as an additional treatment
for moderate to severe
spasticity in multiple sclerosis.
Seb's family are raising # 70,000 to pay
for a procedure called Selective Dorsal Rhizotomy (SDR) which will remove or reduce the
spasticity in his legs so that he can move more freely.
The government created a bit of a problem
for itself when it allowed GW Pharmaceuticals to grow cannabis under license in order to produce Sativex - a cannabis tincture used to treat
spasticity in multiple sclerosis patients.
Previously, Russo oversaw international clinical trials
for Sativex, an oral spray made by GW Pharmaceuticals in Salisbury, U.K., that has been approved in 27 countries
for treating
spasticity caused by multiple sclerosis and in Canada
for certain types of pain.
For upper limb
spasticity, three of the drug formulations — abobotulinumtoxinA, incobotulinumtoxinA, and onabotulinumtoxinA — are effective in reducing excess muscle tone and should be offered.
The guideline determined that botulinum toxin is generally safe and effective
for treating
spasticity in adults, cervical dystonia, blepharospasm and chronic migraine, according to guideline author David M. Simpson, MD, with the Icahn School of Medicine at Mount Sinai in New York, NY, and a Fellow of the American Academy of Neurology.
«There have been a series of discoveries over the last five years showing that proteins that control RNA degradation are very important
for brain development and, when they are mutated, you can have
spasticity or other movement disorders,» Dr. Colak says.
Botox — best known
for its ability to smooth wrinkles — has been extremely useful
for the treatment of over-active muscles and
spasticity as it promotes local and long - term paralysis.
The evidence
for benefits was strongest
for treating chronic pain, reducing chemotherapy - induced nausea and vomiting, multiple sclerosis patients have reported that it reduces
spasticity — muscle tightness and movement difficulties — although when the measurements are taken by a doctor the evidence of reduced
spasticity was weaker.
There is «conclusive or substantial evidence» that marijuana or related compounds can effectively treat chronic pain, nausea caused by chemotherapy treatment
for cancer, and
spasticity caused by multiple sclerosis, according to a report published today by the National Academies of Sciences, Engineering, and Medicine.
Loss of function mutations in CTNNB1 have been reported in individuals with intellectual disability [MIM # 615075] associated with peripheral
spasticity, microcephaly and central hypotonia, suggesting a recognisable phenotype associated with haploinsufficiency
for this gene.
A January 2017 report issued by the National Academies of Sciences, Engineering, and Medicine, which provides nonpartisan guidance
for national decision - makers, found substantial evidence that cannabis is effective
for treating chronic pain, nausea and vomiting, and in reducing
spasticity symptoms in multiple sclerosis, but also found clear risks
for pregnant women and youth.
Smoking cannabis was superior to smoking placebo
for symptom and pain reduction in individuals with multiple sclerosis having excessive muscle contraction or treatment - resistant
spasticity.
On October 21, 2008, Avigen announced that the top - line data from its AV650 trial
for the treatment of
spasticity in patients with multiple sclerosis did not meet its primary endpoint.