Sentences with phrase «for specific markers»

The two groups were monitored after the race by assessing the blood for specific markers of physiological stress that helps evaluate the body's ability to recover.

He and his colleagues extracted mitochondrial DNA from the samples and screened it for specific markers, using a technique called restriction mapping.

«One can imagine that a SLIM - based tissue imager will scan biopsies in a clinic and, paired with software that is intelligent enough to look for these specific markers, will provide the pathologist with valuable new information.

The two groups were monitored after the race by assessing the blood for specific markers of physiological stress that helps evaluate the body's ability to recover.

Not exact matches

For one, it would give them three specific biological markers to hone in on: The buildup of beta amyloid and tau proteins, which cause brain plaques associated with Alzheimer's, and brain nerve cell death.

This latest study builds on Dr Sathe's previous work in developing a bank of marker proteins for a variety of nuts, although that research did not allow for investigation of specific nut allergens.

Some teams use zonal and have specific man marker for a dangerous player... shearer, Carroll etc who did or can excel at putting the ball in the back of the net from a corner.

The company wanted to use it as a diagnostic marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.

Abiraterone's ability to lower levels of prostate - specific antigen, a surrogate marker for prostate cancer, was slightly greater for patients in the low - dose with food group when measured at 12 weeks.

But in May, the U.S. Food and Drug Administration for the first time allowed the use of an existing approved drug, Keytruda, to treat any solid tumor bearing a specific genetic marker.

Further, he noted that increased plasma CRP levels are linked to various clinical conditions, which means that CRP is not a highly specific marker for delirium.

The analysis checked the tissue samples for specific genetic markers found in brown or beige fat.

Take, for example, prostate - specific antigen (PSA), which is a blood serum marker used to test men for prostate cancer.

University Professor of Applied Physics Stephen Arnold and his team at the New York University Tandon School of Engineering have made a discovery that could lead to Star Trek - like biosensor devices capable of flagging the barest presence in blood of a specific virus or antibody, or protein marker for a specific cancer; or sniffing out airborne chemical warfare agents while they are still far below toxic levels.

The geographic variation of specific DNA markers was then mapped separately for savanna and forest elephants, which appear to be two separate species.

The Australian researchers isolated a specific DNA marker for femininity in the lizard before exposing three additional clutches of eggs to varying temperatures.

A chromosome - specific BAC library was used to assemble 82 % of the chromosome into 1036 contigs that were anchored with 1443 molecular markers, providing a major resource for genetic and genomic studies.

One of the challenges has been to identify specific markers for metastatic BLBC, which would allow development of drugs and prediction of survival.

All had been treated previously with at least one type of androgen deprivation therapy and had rising levels of prostate specific antigen (PSA), a blood marker for prostate cancer, and radiographic evidence their cancers were becoming resistant.

The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.

Next steps for the team include identifying microbiota metabolites whose levels are either significantly elevated or depleted during diseases such as IBD or cancer, to find disease - specific markers and explore possible roles for these metabolites in disease progression.

Researchers at Karolinska Institutet have identified cell surface markers specific for the very earliest stem cells in the human embryo.

Each of these magnetic markers is designed to target specific sites within biomolecules and thus enables several approaches for the structural analysis of different biomolecules.

The authors believe theirs is the first study to show that mouse mammary gland tissues are sensitive to a mixture of 23 commonly used UOG chemicals, with dose - specific effects on tissue morphology, cell proliferation and induction of intraductal hyperplasias, an overgrowth of cells considered a marker for future breast cancer risk.

A newly published International Osteoporosis Foundation (IOF) and European Calcified Tissue Society (ECTS) Working Group position paper [1] proposes measuring specific bone turnover markers (BTMs) in patients who have initiated use of oral bisphosphonates for postmenopausal osteoporosis as a clinically feasible and practical way to identify low adherence.

For the first time, researchers report identifying a biological marker: the over-production of specific genes that could be a diagnostic indicator of mental illness in female psychiatric patients.

«DNA sequencing procedures... allow for identification of parentage, more distant relatives, founders to new populations, unidentified individuals, population structure, effective population size, population - specific markers, etc.» reports Haig, adding that the result is more sophisticated information crucial to setting species recovery priorities.

We are aware that at Dr. Robert Getzenberg's request, the journal Urology on Oct. 3, 2011, retracted his manuscript entitled, «EPCA - 2: a highly specific serum marker for prostate cancer.»

Cancers would be caught at their earliest stage and other stages of development, and doctors would have the necessary protein or genetic information from these captured cells to customize your treatment based on the specific markers for your cancer.

In a paper published in the journal Nanotechnology [«Static micro-array isolation, dynamic time series classification, capture and enumeration of spiked breast cancer cells in blood: the nanotube - CTC chip»], Panchapakesan's team, which includes graduate students Farhad Khosravi, the paper's lead author, and researchers at the University of Louisville and Thomas Jefferson University, describe a study in which antibodies specific for two markers of metastatic breast cancer, EpCam and Her2, were attached to the carbon nanotubes in the chip.

Some FGF2 - treated cells also expressed markers for the rhombic lip — the structure from which granule cells develop and migrate, and a marker specific to migrating granule precursors by week seven.

With SABT2 as a marker, the researchers show BMP signaling is required for development of tissues specific to the posterior gut region of frogs and mice where the colon develops.

Expanding from their previous studies with mice, the researchers first established that under specific conditions, culturing human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers for the cerebellar plate neuroepithelium — the part of the developing nervous system specific for the cerebellum — within five.

He believes that the two relatively stable groups or enterotypes of bacteria species into which people can be grouped could be valuable markers to predict whether specific diets will work for them or not.

Other methods use chemical or physical markers that allow the operator to find the specific object they are looking for within a thick sample, but those markers can be toxic to living tissue, Popescu said.

To identify and quantitate macrophages within adipose tissue, we immunohistochemically stained sections for the F4 / 80 antigen, a marker specific for mature macrophages (Figure 2; ref.

«But the desired cells often lack a readily accessible surface marker, or that marker is not specific enough, as is the case for cardiac muscle cells.

The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease

Pluripotent cells were cultured in mouse Noggin protein for 5 d and immunocytochemistry was used to detect retinal specific markers.

However, we typically stained each mosaic retina for three or four cell class - specific markers and always detected cells expressing every marker tested (three of three or four of four).

Host (YFP) cells appear red when stained for cell class specific markers, while double - labeled, donor - derived cells (arrows, arrowheads, and carrots) appear yellowish - red.

There are no specific markers to identify them; however, they are negative for hematopoietic cell markers like CD34 / 45 / HLA - DR and express CD90 / 73/105 on their surface 2, 3, 4.

Asialoglycoprotein receptor 1 is a specific cell - surface marker for isolating hepatocytes derived from human pluripotent stem cells.

Stage - specific embryonic antigen - 4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells.

Control and gesicle - treated hiPS cells were assessed for AcGFP1 expression (green), labeled with an antibody specific to pluripotency marker Oct ‑ 4, visualized with a fluorescent - labeled secondary antibody (red), and nuclear - labeled with DAPI (blue).

Another liver - specific protein, Asialoglycoprotein receptor 1 (ASGPR1), is a surface marker for mature hepatocytes [5, 6].

Due to these physiopathological complexity and heterogeneously, one of the major requirements for a successful therapy is the design of a multifunctional nanomedicines that is able to selectively attack specific markers from tumor and stroma cells.

In addition, the presenter will provide guidance on experimental design for multiplexed antibody panels combining phenotypic markers with phospho - specific intracellular targets, and discuss the use of fix and perm kits.

For the detection of specific antigens, the following primary antibodies were used: mouse monoclonal anti-Tuj1 (Covance, Princeton, NJ, USA) as a neuronal marker, rabbit anti-L1 (kindly provided from Dr. Asou)[52] and rat monoclonal anti-L1 (Millipore, Billerica, MA, USA) as granule cell markers, rabbit anti-calbindin D28K (Millipore) as a Purkinje cell marker, and rabbit anti-glial fibrillary acidic protein (GFAP, DAKO, Denmark) as an astrocyte marker.

Cells were stained with antibodies specific for human cell surface markers: CD326 / ESA - FITC, CD24 - PE, and CD44 - PE - Cy7 (BD Pharmingen, San Jose, CA, USA).