Sentences with phrase «for stem cell studies»

Hyun wrote a 2006 commentary piece in Nature in which he argued that just like others who volunteer for research, women should be paid to donate eggs for stem cell studies.

Not exact matches

Tony co-founded the UW Institute for Stem Cell and Regenerative Medicine and chaired the Molecular and Cellular Hematology Study Section for the National Institutes of Health.

February 2, 2017 By Ann Perry http://mbd.utoronto.ca/ When Arif Aziz learned last fall about a new independent study project that was bringing together MBA candidates and PhD students in health sciences and engineering to map the global market for stem cell therapies, he jumped at the opportunity.

However, embryonic stem cells remain the «gold standard,» and studies of all types of stem cells should continue in parallel for the foreseeable future.»

Cauliflower is full of sulfur compounds called glucosinolates such as the powerful sulforaphane and isothiocyanates which have been studied to be very effective for phase II liver detoxification and as cancer stem cell neutralizing agents.

In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study from Sahlgrenska Academy.

The study also found that in addition to its role in determining the sex of somatic cells, Sxl regulation by m6A is required to initiate germline stem cell differentiation for developing eggs.

They also looked for genes not previously studied for having a role in fusing muscle stem cells.

«This new study uncovers for the first time the dynamic of stem cells during wound healing and identifies new molecular players associated with skin regeneration.

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

Although the U.S. government puts stringent restrictions on funding for research on embryonic stem cells, individual states such as California have set up institutes to perform that work and general stem cell studies.

«I think this is the best option we have ever had,» says Renee Reijo Pera, director of Stanford University's Center for Human Embryonic Stem Cell Research and Education in California, who wasn't involved in the study.

New treatments for spinal cord injury, including stem cells, gene therapy and electrical stimulation, are being studied.

«This study signals a big change in thinking, because it provides simple and efficient tools for scientists to study stem cell creation in a stage - by - stage manner.

This fits with studies we've conducted in the past in which we found that the gene primes blood stem cells for leukaemic transformation.»

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

We believe that they will also lead to the development of a whole new range of therapies for neurodegenerative diseases of the central nervous system,» explains corresponding author of the study Jihwan Song, professor and director of Neural Regeneration and Therapy Group at the CHA Stem Cell Institute of CHA University.

According to Izpisúa Belmonte, who is also a professor at the gene expression laboratories of the Salk Institute for Biological Studies in San Diego, California, CMRB aims to become «a research centre of excellence in south Europe in the line of world - recognized institutions such as the Salk or the Whitehead institutes, where both pre - and postdoctoral researchers receive multidisciplinary training of the highest quality» in stem cell biology and cell regeneration.

Another problem is that in its July 2009 Guidelines on Human Stem Cell Research, NIH spelled out specific requirements about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law School.

An update search enlarged the pool of study data, but did not change the content of the conclusion of the benefit assessment of stem cell transplantation (SCT) for multiple myeloma conducted in 2012.

«Blood stem cells study could pave the way for new cancer therapy.»

Several studies have supported a role for cancer stem cells in the aggressive brain tumors called glioblastoma, but those studies involved inducing human tumors to grow in mice, and as such their relevance to cancer in humans has been questioned.

It also provides novel insight into human mesenchymal stem cell - heart cell interactions that can guide future experimental studies to understand the mechanisms underlying mesenchymal stem cell therapy for the heart.

Studying mice with injuries to the lining of the stomach, the researchers blocked the animals» ability to call on stem cells for help in the stomach.

«These results provide the basis for the potential implementation of 5 - LO - inhibitors as stem cell therapeutic agents for a sustained AML cure, although this must be investigated further in preclinical and clinical studies in humans,» explains Dr. Ruthardt.

The new rules state that stem cells can be used if they are part of a study approved by the federal government, or if the protocol has been approved by an Institutional Review Board (IRB) that provides ethical review for research involving human volunteers.

Dr Lee Campbell, Research Projects and Science Communications Manager at Cancer Research Wales, who part - fund the study, commented: «This is an exciting breakthrough as cancer stem cells are thought to be responsible for the failure of many cancer treatments and the re-emergence of cancers, often many years after the initial disease.

In a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxic.

While some previous studies found that maintenance lenalidomide after autologous hematopoietic stem cell transplant improved overall survival for newly diagnosed multiple myeloma patients, others showed no benefit to this approach.

«Lenalidomide maintenance following autologous stem cell transplant can now be considered a standard of care for people with multiple myeloma,» says Dr. McCarthy, senior author on the meta - analysis and Principal Investigator of the U.S. study, CALGB (Alliance) 100104.

A stem cell core facility at CHOP, directed by study co-author Deborah French under the auspices of the hospital's Center for Cellular and Molecular Therapeutics, generated the iPSCs lines used in these studies.

The Gendered Innovations website offers case studies ranging from sex differences in stem cell characteristics to assistive technologies for aging men and women.

By tinkering with the medium in which cells are grown, researchers at the Salk Institute for Biological Studies created a type of stem cell with a survival rate of 30 to 40 percent, vs. 1 percent.

«Our study suggests that ALDH1A3 is a potentially functional biomarker for mesenchymal glioma stem cells, and that inhibiting that enzyme might offer a promising therapeutic approach for high - grade gliomas that have a mesenchymal signature,» says principal investigator Ichiro Nakano, MD, PhD, associate professor of neurosurgery at the OSUCCC — James.

A study in the International Society for Stem Cell Research's journal Stem Cell Reports, published by Cell Press on November 20 shows that a Sox2 protein, alone or in combination with another protein, Ascl1, can cause nonneuronal cells, called NG2 glia, to turn into neurons in the injured cerebral cortex of adult mice.

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

The teams are currently working on the fabrication of 3D structures from the blend suitable for implantation in patient joints with future studies focusing on understanding the peculiar interactions between the blend and stem cells towards refining the quality of regenerated cartilage.

The pluripotent stem cell - derived muscle fibers develop reservoirs of «satellite - like cells» that are necessary for normal adult muscles to repair damage, while the muscle from the previous study had much fewer of these cells.

For this study, Nakano and his collaborators used cancer cells from 40 patients with high - grade gliomas, focusing on tumor cells with a stem - cell signature.

Their research should serve as a baseline for future studies of U.S. businesses engaged in direct - to - consumer advertising of purported stem cell interventions.

«The discovery introduces — for the first time — stem cell - based «biological resynchronization» as a novel means to treat cardiac dyssynchrony,» says Andre Terzic, M.D., Ph.D., senior author of the study.

In the study published in the journal Science Signaling, the team led by LLuís Espinosa, investigator of IMIM's research group into stem cells and cancer, have shown that inhibition of endosomal activity is a potential therapeutic strategy for the treatment of cancers with the BRAF mutated gene.

That message, delivered in two studies published today, is both good news and bad news for researchers who hope to use so - called induced pluripotent stem cells (iPS cells) to study diseases and perhaps some day treat patients.

But the Harvard stem cell and regenerative biologist Amy Wagers, a co-author on three of the mouse papers, said in an email to STAT that she does not agree that her teams» studies provide a scientific basis for Maharaj's clinical trial.

And the setback followed a major stem cell scandal in which biologist Haruko Obokata of the Riken Center for Developmental Biology was found to have falsified data in studies, published in 2014, that claimed a new method of achieving pluripotency.

In prior studies, Desgrosellier and team found that αvβ3 expression acts as a switch during early pregnancy to activate normal mammary stem cells as the body remodels to prepare for a baby.

And it suggests that stem cells derived from embryos should remain the primary reference for iPS cells when researchers want to compare how cells from diseased patients behave, says Nissim Benvenisty of Hebrew University of Jerusalem, who has studied differences between ES cells and iPS cells derived from carriers of fragile X syndrome.

«Breast cancer stem cells pose a serious problem for therapy,» says lead study investigator Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine, director of the Vascular Biology Program at the Johns Hopkins Institute for Cell Engineering and a member of the Johns Hopkins Kimmel Cancer Center.

Exploiting the same pre-clinical model used for their studies, the researchers are testing the efficacy of this kind of drug candidates against cancer stem cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of human breast cancer.

In a new study the PhD students Jan Hoeber, Niclas König and Carl Trolle, working in Dr.Elena Kozlova's research group transplanted human stem cells to an avulsion injury in mice with the aim to restore a functional route for sensory information from peripheral tissues into the spinal cord.