Sentences with phrase «for structural studies»

These samples are useful for both structural studies and ligand binding assays.

Here, we present the 2.8 Å crystal structure of human CB1 in complex with AM6538, a stabilizing antagonist, synthesized and characterized for this structural study.

Not exact matches

Ronald Burt is a sociologist in the University of Chicago's Booth School of Business who for more than 30 years has studied the phenomenon of «structural holes,» i.e., gaps within organizations.

The university also ranks among the top 50 universities in the world for linguistics, computer science and information systems, civil and structural engineering, electrical and electronic engineering, mechanical engineering, agriculture and forestry, psychology, chemistry, environmental studies, materials science, physics and astronomy, and other fields.

However, the Organization for Economic Co-operation and Development studied structural separation (links to PDF) across various industries several years ago and didn't find that to be the case:

But according to a recent C.D. Howe study, the federal government could run a permanent structural deficit of 1 % of GDP ($ 20 billion) and still maintain a stable debt ratio of 25 %, which happens to be the Conservative government's target for 2022.

The study found that 72 percent of African Americans in predominantly black churches believe that the reasons for racial inequality are structural, rather than an individual's lack of motivation.

In contrast, the social - science approach seeks structural and cultural contexts for personages in the past by studying the actual behavior of contemporary people with similar social structures, values and human types.

The personnel of FOODPRO are pleased to offer a complete range of consulting engineering services from studies (planning, feasibility, site selection, etc.) through construction and equipment installation management including all the engineering disciplines (industrial refrigeration, electrical, structural, etc.) necessary for complete plans and specifications.

This study radiotracked several species of resident forest birds in the Coto Brus province of southern Costa Rica, now «dominated by sparsely - shaded coffee farms» — recall that in my post on coffee growing in Costa Rica that most farms, including those marketed as «shade» coffee, have few shade trees of only a couple of species, and lack the structural complexity necessary for true biodiversity preservation.

When an architectural study showed that the mansion could not handle a third expansion without costly structural work, the City Council, library board and Park District hammered out a land swap in which the Park District gave the city and library 27,000 square feet of land at Prospect Street near the Elmhurst Art Museum in exchange for 52,000 square feet of land on the north and south sides of the mansion.

Hein advised that bridges over creeks that crested would be studied by engineers for structural damage.

Farmer argues that «careful study reveals that state power has been responsible for most human rights violations and that most violations are embedded in «structural violence» — social and economic inequities that determine who will be at risk for assaults and who will be shielded.

After productively using nuclear magnetic resonance (NMR) spectroscopy to study protein structure during a Ph.D., she switched to structural mass spectrometry for her postdoc in the United Kingdom.

«This study is the first to demonstrate evidence for both keratin and melanosomes, using structural, chemical and molecular methods,» says Pan.

«We've known for some time that invadopodia are driven by protein filaments called actin,» said study leader Louis Hodgson, Ph.D., assistant professor of anatomy and structural biology at Einstein.

The study, published by the journal Science via First Release on April 12, paves the way for determining the structures of other functional states of the ATP synthase, which has been the subject of structural studies for decades in labs across the globe.

«For now, this study represents a proof of concept that monobodies can be designed to work with very difficult targets to make inhibitors and determine structural information,» he adds.

«Cryo - EM has revolutionized structural biology, particularly in the last three years, with the invention of new kinds of electron detectors for the microscope,» says Michael Rossmann, a physicist and microbiologist at Purdue University in West Lafayette, Ind., and a coauthor of the Zika mapping study.

«For the first time we have a room - temperature, high - resolution structure of one of the most difficult - to - study but medically important families of membrane proteins,» said Vadim Cherezov, a structural biologist at The Scripps Research Institute (TSRI) who led the research.

This study, titled «Enamel Hypomineralization and Structural Defects in Amelotin - deficient Mice,» is published in the OnlineFirst portion of the Journal of Dental Research: the journal for dental, oral and craniofacial research.

Marieta Pehlivanova, Joseph Kable, Theodore Satterthwaite and colleagues studied whether this relationship between cortical thickness and reward preference holds true for teens, whose brains are undergoing dramatic structural changes.

A study by Florian Krause from the Donders Institute in Nijmegen shows for the first time that these individual differences have a structural basis in the brain.

The robust study, years in the making, also applied advanced structural and 3 - D computer modeling analysis to identify the underlying basis for the new compound's success.

But the technique does not lend itself well to studying structural materials, such as steel, that are needed to build, for example, aircraft wings, bridges or engines.

«Our study emphasizes the importance of individualized therapy strategies and lifestyle interventions in order to prevent structural knee joint degeneration as early as possible in obese and overweight patients at risk for osteoarthritis or with symptomatic osteoarthritis,» Dr. Gersing said.

Different as they appear at first glance, they share basic structural features, according to a new study: characters with vertical symmetry (like the Roman letters A and T) and a preference for vertical and horizontal lines over oblique lines (like those in the letters X and W).

After some investigation I found out that the European School for Advanced Studies in Reduction of Seismic Risk (ROSE School) at the University of Pavia, in northern Italy, had the status of a Marie Curie Training Site in civil engineering, more specifically in the field of structural - earthquake engineering.

So that scientists around the world may continue to look for fundamental structural insights, the full, interactive imaging dataset is viewable at Mouse Connectome Project, providing a resource for researchers interested in studying the anatomy and function of cortical networks throughout the brain.

The three studies, published in tomorrow's issue of Nature, push the limits of structural biology and set an important precedent for understanding how molecular pumps work, including those in humans, notes Werner Kühlbrandt of the Max Planck Institute of Biophysics in Frankfurt am Main, Germany.

As detailed in an accompanying guide, NIST Disaster and Failure Studies Data Repository: The Chile Earthquake Database — Ground Motion and Building Performance Data from the 2010 Chile Earthquake — User Manual (NIST GCR 15 - 1008), the new collection contains tabular data on ground motion, damage and structural properties, as well as nearly 25,000 photographs and drawings, for 273 buildings and structures impacted by the 2010 Maule, Chile, quake, and for comparison, their response to the 1985 quake centered offshore of Valparaíso, Chile, 370 kilometers (230 miles) to the north.

LiWang's structural biology lab uses nuclear magnetic resonance (NMR) spectroscopy, the parent technology for MRI, to study the protein structure and dynamics of biological molecules and then uses the structures to gain insights into their function.

Many of the genomic projects will eventually lead to interesting targets for structural biological studies.

The study also reports the structural details of the viral gHgLgO complex bound to the cellular PDGFRα, demonstrating that the gO molecule is essential for the binding to PDGFRα and thus represents the key component that triggers the infection of the host.

In the last decade, graphene has been intensively studied for its unique optical, mechanical, electrical and structural properties.

But the technique's most valuable application will likely be using sound to probe the structural properties of objects — studying metal alloys, for instance, by blasting sound at them.

The Fraunhofer Institute for Structural Durability and System Reliability LBF in Darmstadt, Germany has now solved this problem together with the Institute for Textile Technology (ITA) of the RWTH Aachen in the exploratory study «Bastfix,» which is funded by the German Federal Ministry of Education and Research (BMBF).

By joining forces with Professor Wim Versées at the VIB research center for structural biology, the scientists were able to figure out the three - dimensional structure of Skywalker, making it possible to study the protein in microscopic detail.

In the study, jointly funded by the National Institute of Mental Health and the United States Department of Veterans Affairs, senior author Mark Miller, also from the National Center for PTSD, and colleagues examined the associations between PTSD, metabolic syndrome, and structural integrity of the brain.

For the new study, researchers looked at the brain's structural connectome, a map of white matter tracts that carry signals between different areas of the brain.

Structural data was available for 10 studies, with a total of 263 patients with BPD and 278 healthy subjects.

Still, Sheehan said neuroscience already is one of the leaders in data sharing and management, with such resources as the NIH - funded National Database for Autism Research; an NIH - Defense Department sponsored data base on traumatic brain injury; the NIH - funded Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC), which helps researchers to develop, share and collaborate on software tools for doing functional and structural imaging studies of the brain; and the Neuroscience Information Framework, an NIH initiative that makes neuroscience resources - data, materials, and tools - accessible via any computer connected to the Internet.

In two papers published back - to - back in Biotechnology Journal online on November 30, 2016, a Korean research team led by Professor Kyung - Jin Kim at Kyungpook National University and Distinguished Professor Sang Yup Lee at the Korea Advanced Institute of Science and Technology (KAIST) described the crystal structure of PHA synthase from Ralstonia eutropha, the best studied bacterium for PHA production, and reported the structural basis for the detailed molecular mechanisms of PHA biosynthesis.

The study used powerful electron microscopes at the University of Leeds» Astbury Centre for Structural Molecular Biology.

«However, this proof - of - concept study defines a roadmap for future studies investigating the genetic covariance between structural / functional brain phenotypes and risk for psychiatric disorders,» Sullivan said.

The ASU team involved in this study includes four faculty and their research teams (John Spence, Uwe Weierstall, Petra Fromme and Raimund Fromme) from the Departments of Physics and Chemistry and Biochemistry who are members of the new Center for Applied Structural Discovery at the Biodesign Institute.

«This study highlights how neutrons are an unrivaled probe for identifying the location of hydrogen atoms in biological systems, providing us with an unprecedented level of structural detail for this important enzyme,» LADI - III beamline scientist Matthew Blakeley said.

To figure out what survivin is up to, structural biologist Joseph Noel of the Salk Institute for Biological Studies in La Jolla, California, and colleagues took the first good look at its three - dimensional structure.

«Our initial research studied the variability from 16 recycled aggregate sources in the Midwest and quantified ways to pre-qualify the material for structural applications,» Kurama said.

More importantly, says Greenberg, the BRCC36 - KIAA0157 complex may represent an attractive drug development target for inflammatory diseases — an effort that should be aided immeasurably by the detailed structural information this study provides.