Sentences with phrase «for subgroups of patients»

The pharmaceutical industry will have to shift from a business model that emphasizes blockbuster drugs to one producing many specialized medications for subgroups of patients.

«New schizophrenia treatments may be effective for subgroup of patients.»

For this subgroup of patients, a promising new treatment called Fecal Microbiota Transplantation (FMT) brings hope.

Not exact matches

«In the future, we hope that this information can be utilized in dividing the patients into different genetic susceptibility groups for clinical drug trials, thus increasing the chances of identifying the best possible treatment for each subgroup,» he continues.

As treatments for HCV have evolved, genotype 3 patients have become the most difficult subgroup of patients to cure.1 Although there have been recent advances in direct - acting antiviral therapies for HCV genotype 1, genotype 3 remains a challenge and is a highly prevalent strain of the infection globally, with a particularly high concentration of cases in Asia.1

The large size and diverse racial / ethnic makeup of the Breast Cancer Family Registry allowed the researchers to evaluate mortality risk across different subtypes of breast cancer and subgroups of patients, and adjust for confounding factors.

Clinical features of major depressive disorder (MDD) may help identify specific subgroups of depressed patients based on associations with genetic risk for major psychiatric disorders, reports a study in Biological Psychiatry.

In addition, the subgroup of patients with unmethylated MGMT promoter and HLA - A2 appear to particularly benefit,» said Patrick Y. Wen, MD, director of the Center for Neuro - Oncology at Dana - Farber Cancer Institute and professor of Neurology, Harvard Medical School, who will present the data at the conference.

Commenting on the findings, Prof Robert Pirker, programme director for lung cancer at the Vienna General Hospital in Vienna, Austria, not involved in the study, said: «This subgroup analysis shows that the effect of necitumumab was slightly greater in patients with EGFR expressing tumours than it was in the entire SQUIRE population.

«We have identified a subgroup of older patients at sufficiently low risk of recurrence for whom omission of postoperative radiotherapy after breast - conserving surgery and adjuvant endocrine therapy is a reasonable option.

Many international care guidelines call for further research addressing the different subgroups of patients with lower back pain.

The authors conclude that FL118 - based therapy may be beneficial for a subgroup of cancer patients with tumors such as chronic lymphocytic leukemia and melanomas, in which MdmX overexpression confers treatment resistance.

Our tentative, though testable, findings may provide a direction for the development of personalized treatments for a patient subgroup whose illness is associated with a dysregulation of brain glutamate function.»

The finding that one in four patients had weight gain suggests that particular subgroups of patients treated for Q fever are vulnerable to weight gain.

Where research uncovers possible mechanisms for disease, those working in drug discovery can use these data to develop novel diagnostic or monitoring tools, to develop therapies that address the biological pathways concerned, or to develop companion diagnostics to ensure that new — or existing — therapies are targeted at the correct subgroup of patients.

«Detection of ctDNA allows identification of a subgroup of patients at high risk of early relapse and inferior survival, allowing stratification of patients to adjuvant regimens associated with higher toxicity but greater potential for efficacy.»

For example, medications that may not appear to work well in a group of ADHD patients as a whole, may be effective for one particular subgroup that arises from a specific causal pathwFor example, medications that may not appear to work well in a group of ADHD patients as a whole, may be effective for one particular subgroup that arises from a specific causal pathwfor one particular subgroup that arises from a specific causal pathway.

Not all lung cancers are linked to ALK mutations, so the drug crizotinib, which inhibits the mutant enzyme, is prescribed only for that small subgroup of lung cancer patients.

We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.

Readmission rates of patients were lower for female physicians than for male physicians for all subgroups except for the least sick patients.

To be able to evaluate the prognosis for individual patients the disease is divided into subgroups based on for example the presence or absence of genetic alterations.

Little is known about the influence of treatment techniques based on DP on outcomes for patients classified as high psychosocial risk using the Subgroups for Targeted Treatment (STarT Back Screening Tool).

Lin, Y. S., Lin, L. C., and Lin, S. W. Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow - up of a double - blind randomized study with subgroup analysis.

They focused on the efficacy and safety of tPA treatment and also looked for any factors or patient subgroups that might affect treatment outcome.