Sentences with phrase «for subsequent development»

The peer group represents an important and unique context for the development of a wide range of skills and competencies in early childhood.1 Simply stated, «playing with friends» helps young children acquire and practice social (e.g., resolving conflicts), cognitive (e.g., perspective - taking), emotional (self - regulation) and communicative skills that provide foundations for their subsequent development.

Such was the case with Chicago's Center for Green Technology, the country's first LEED Platinum municipal building — and an inspiration for subsequent development both in Chicago and nationwide.

With a lovely definition: «lock - in: The process whereby an idea or a model becomes the basis for subsequent development, so that its flaws can not be remedied without dismantling the entire system that is built upon it.»

Ranging across Johns's entire career — from his breakthrough paintings of the 1950s, which paved the way for the subsequent development of Pop art and Minimalism, to his most recent work — the survey offers a rich overview of the visual and philosophical inquiries central to Johns's practice and illuminates his enormous impact on artistic developments following Abstract Expressionism.

By the mid-1920s, the importance of cubism for American artists was in decline, but the movement was the stepping - off point for the subsequent development of American abstract art.

Ranging across Jasper Johns's entire career — from his breakthrough paintings of the 1950's, which paved the way for the subsequent development of pop art and minimalism, Jasper Johns has had numerous museum retrospectives throughout his career, including paintings, drawings, prints as well as a host of other themes; recent highlights include the landmark 1997 exhibition» «Jasper Johns: A Retrospective» at the Museum of Modern Art, curated by Kirk Varnedoe and the breathtaking 2008 «Jasper Johns: Gray» at the Art Institute of Chicago and The Metropolitan Museum of Art.

The Barbizon painters helped prepare for the subsequent development of the impressionist schools.

Vaccination of pet and research dogs with polyvalent vaccines containing rabies virus or rabies vaccine alone was recently shown to induce production of antithyroglobulin autoantibodies, a provocative and important finding with implications for the subsequent development of hypothyroidism (Scott - Moncrieff et al, 2002).

In response to extracellular matrix signalling, these cells undergo epithelialization and create an apical surface in contact with a cavity, a fundamental event for all subsequent development.

Under the companies» original strategic agreement, AstraZeneca holds exclusive access to select any target of its choice in cardiometabolic diseases, as well as select targets in oncology, over a period of up to five years for subsequent development in mRNA.

This discovery provided the physiological basis for subsequent development of fMRI and caused researchers to reconsider the dogma that brain uses oxidative phosphorylation exclusively to fuel its functional activities.

«This research highlights the potential role of individual differences in verbal abilities during childhood as a risk factor for the subsequent development of alcohol use during adolescence and young adulthood,» said Michael Windle, professor and chair of the Rollins School of Public Health at Emory University.

· The timing alone of the introduction of gluten in the diet is not an independent risk factor for subsequent development of gluten intolerance.

NKp46 was critical for the subsequent development of antiviral and antibacterial T cell responses, which suggests that the regulation of NK cell function by NKp46 allows for the optimal development of adaptive immune responses.

But his clear emphasis upon it at the moment when the whole apparatus of public, «institutional» religion had been swept away, was of the first importance for all subsequent development.

While cognitive tests have a slightly closer correlation with job success, personality tests are useful both as a basis for interview questions and for subsequent development.

In his sober assessment of the current state of post-conciliar Catholicism, Ross Douthat argues that Cardinal Newman's 1845 theory of doctrinal development should be updated to account for subsequent developments.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

Among the factors that could cause actual results to differ materially are the following: (1) worldwide economic, political, and capital markets conditions and other factors beyond the Company's control, including natural and other disasters or climate change affecting the operations of the Company or its customers and suppliers; (2) the Company's credit ratings and its cost of capital; (3) competitive conditions and customer preferences; (4) foreign currency exchange rates and fluctuations in those rates; (5) the timing and market acceptance of new product offerings; (6) the availability and cost of purchased components, compounds, raw materials and energy (including oil and natural gas and their derivatives) due to shortages, increased demand or supply interruptions (including those caused by natural and other disasters and other events); (7) the impact of acquisitions, strategic alliances, divestitures, and other unusual events resulting from portfolio management actions and other evolving business strategies, and possible organizational restructuring; (8) generating fewer productivity improvements than estimated; (9) unanticipated problems or delays with the phased implementation of a global enterprise resource planning (ERP) system, or security breaches and other disruptions to the Company's information technology infrastructure; (10) financial market risks that may affect the Company's funding obligations under defined benefit pension and postretirement plans; and (11) legal proceedings, including significant developments that could occur in the legal and regulatory proceedings described in the Company's Annual Report on Form 10 - K for the year ended Dec. 31, 2017, and any subsequent quarterly reports on Form 10 - Q (the «Reports»).

Focusing exclusively on high - potential products that align with health system priorities and patient needs, EXCITE's pre-market approach identifies opportunities for improvement while products are still in development, resulting in better technologies for patients and lower system costs, while also streamlining the subsequent adoption process.

Within the context of this broad strategic assessment, the Board judged at the time of the June meeting that the case for an easing was not sufficiently strong and, in the event, subsequent developments tended to weaken that case further, so that the cash rate was again held unchanged at the July and August meetings.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

That God never accomplishes all that is envisioned does not mean that God is sterile, for to have power means to share in the development of one's «sell» and to effect the becoming of subsequent actualities.

Newman goes on to argue that claiming that faith must always proceed works in living the Christian life is «mistaking a following in order of conception for a following in order of time...» In fact, he writes, our works are «the concomitant development and evidence, and instrumental cause, as well as the subsequent result of faith.»

My concern at this juncture is with the biblical witness itself, as crucial springboard for — and basis for judgment of — subsequent developments in the church's theologizing.

Although the subsequent chapters will develop these matters in detail, it might be helpful at this point to delineate briefly the main lines of development that Hartshorne has laid down for process theology.

The generic character of John XXIII's original intentions for the Council, of course, was essentially responsible for much of the subsequent struggle between the Council Fathers and the Roman curia, the latter being accustomed to dealing with «live issues» rather than with general goals of development.

Otherwise, what reason do we have for supposing that God, as «author of the whole drama,» meant the statement to be understood, in the light of subsequent developments, as a reference to humanity's future redemption?»

In Jesus Christ, prepared for through the long preceding development of Jewish religion, and His meaning apprehended through the long centuries of subsequent Christian experience, man is given a vivid and striking disclosure of the eternal Reality; and given it not through the retailing of information but through the whole content of a Life.

If Isaiah's Messianism has an eschatological flavor, that is, if it anticipates a growing concern in subsequent centuries with the «last things,» we may remark that this is, for Isaiah, the goal of history; that Isaiah may indeed be the father of Jewish and Christian eschatology; but that for Isaiah it is a «natural» and consistent development of a very real covenant history.

It is my impression that, on the European continent, it is the basis for almost all subsequent philosophical developments.

It has often happened, however, that scientific developments have had major significance for subsequent philosophical discussion of problems of the one and the many.

17:50 — 17:55 Introduction of NETCODE: The Network for Global Monitoring and Support for Implementation of the International Code of Marketing of Breast - milk Substitutes and Subsequent Relevant WHA Resolutions Dr Francesco Branca, Director, Nutrition for Healthy Development, WHO

An infant must learn to attach and suckle properly at the breast during the first few days of life to successfully establish breastfeeding.1,, 2 Early oral experiences that require sucking mechanics different from those required for breastfeeding are believed to contribute to the development of improper latch and subsequent breastfeeding failure — a problem described as nipple confusion.2 — 4 The avoidance of pacifiers was included as 1 of 10 steps for successful breastfeeding in the 1990 Innocenti Declaration on maternity services and breastfeeding, and many experts recommend that mothers who are breastfeeding avoid exposing their infants to artificial suckling experiences including use of pacifiers.5 — 7

However, in malnourished populations motor development may be a useful predictor of subsequent human function.5 A study conducted in Denmark6 found a positive relationship between breastfeeding duration and an earlier ability to crawl and perform the «pincer grip» after adjusting for potential confounding variables.

The Minister however in a subsequent defense said the amount was for the creation of different websites for the new development authorities; Northern Development Authority, Coastal Development Authority, and the Middle Belt Developmentdevelopment authorities; Northern Development Authority, Coastal Development Authority, and the Middle Belt DevelopmentDevelopment Authority, Coastal Development Authority, and the Middle Belt DevelopmentDevelopment Authority, and the Middle Belt DevelopmentDevelopment Authority.

[3] This shouldn't be terribly surprising given the Republican preference for development - heavy defense spending; the ramp - up of defense spending under Bush following the September 11 attacks and subsequent wind - down under Obama; and partisan differences over certain forms of applied research, which some Republicans believe is better left to the private sector.

The effects of child sexual abuse include increased risk for development of severe mental, physical and behavioral health disorders; sexually transmitted diseases; self - inflicted injury, substance abuse and violence; and subsequent victimization and criminal offending.

A subsequent project involved the development, dissemination and analysis of a preliminary global questionnaire to elicit the views of scientists, engineers and health professionals as to the meaning of the right; and organization of a briefing for the United Nations Committee on Economic, Social and Cultural Rights to inform its development of a General Comment on the right.

As reported by Theodore Kotchen et al. and Howard Dickler et al. in The Journal of the American Medical Association in 2004 and 2007, respectively, about 40 % of M.D.s with K08 (mentored clinical scientist development) awards do not even apply for a subsequent first independent (R01) grant.

Our experience with mp3 and the subsequent technologies served as a good measure for those developments,» says Max Neuendorf, group manager of the IIS Audio and Speech Coding team.

Each participant was enrolled at infancy, between 2004 and 2010, and followed in 3 to 6 months intervals for 10 years to track any development of islet autoantibodies and subsequent type 1 diabetes.

This year they included the physics prize awarded to Rainer Weiss, Barry Barish and Kip Thorne for the development of the Laser Interferometer Gravitational - Wave Observatory (LIGO), and the subsequent direct detection of gravitational waves.

The degree to which this innate tendency to appreciate the taste of salt is modified by subsequent experience is a research area ripe for further investigation, particularly because high salt intake has been implicated in the development and / or maintenance of elevated blood pressure.

For their outstanding contribution to research into the properties of clad optical fibres and their subsequent successful development leading to the commercial production of such fibres which are playing an increasing role into the field of communications.

The objectives to achieve within the 4 years of the NAREB project are: 1 / to select antibacterial molecules and design nanocarriers with strong antibacterial activity, 2 / to test in vitro and in vivo the best therapeutic combinations including innovative genomic and bioimaging approaches, 3 / to assess safety, regulatory and production (GLP / GMP) aspects for the most promising nanoformulations, and 4 / to establishing the Clinical Development Plan for the preparatory work for the subsequent clinical testing of the selected nanoformulations.

demonstrate that consumption of a peanut - containing snack by infants who are at high - risk for developing peanut allergy prevents the subsequent development of allergy.

The results of the Immune Tolerance Network's (ITN) «Learning Early About Peanut» (LEAP), discussed on February 23, 2015 at the American Academy of Allergy, Asthma & Immunology Annual Meeting and published in the New England Journal of Medicine, demonstrate that consumption of a peanut - containing snack by infants who are at high - risk for developing peanut allergy prevents the subsequent development of allergy.

As Head of Project Leader Unit, Nicolas is in charge of the pharmaceutical development and subsequent production of vaccines - for use in clinical trials - directly funded by the European Vaccine Initiative (EVI), and European projects funded from other sources coordinated by EVI.