Sentences with phrase «for synaptic transmission»
Important aspects are how nerve endings provide glutamate for synaptic release and how they recover released glutamate for reuse, as well as how synapses provide energy for synaptic transmission and how astrocytes can modulate neuronal function.
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«You wouldn't have time in the speed required for synaptic transmission to make the vesicles, load them up, and put them in the active zone ready to release them.
Working from the same data that revealed the brain waves, the team found the source was also moving too slow for synaptic transmission and a little too fast for diffusion.
Not exact matches
The extracellular space's fluid — a reservoir of ions critical for electrical activity and synaptic transmission — appears as tiny black spaces among white filaments and blobs.
Presynaptic injection of antibodies specific for VAP - 33 inhibited synaptic transmission, which suggests that VAP - 33 is required for the exocytosis of neurotransmitter.
This regulation is spectacularly apparent in the exquisite speed and precision of synaptic exocytosis, where synaptotagmin (the calcium - ion sensor for fusion) cooperates with complexin (the clamp activator) to control the precisely timed release of neurotransmitters that initiates synaptic transmission and underlies brain function.
It is quite a significant discovery, especially when you consider that many neurological diseases, such as Parkinson's, ALS or dementia, but also speech or motion disorders for instance, are caused by the disruption of synaptic transmission.»
The neurons in the cerebral cortex responsible for ensuring the transmission of the relevant information, then modify the synaptic connections that they have with other neurons.
These data suggest that increased inhibitory synaptic transmission may contribute to human ASDs and that the R451C knockin mice may be a useful model for studying autism - related behaviors.
Because of its critical importance for understanding the brain, its role in our capability to learn and to remember, and the many neurological and psychiatric disorders that involve synapses, a molecular understanding of chemical synaptic transmission has been one of the holy grails of neuroscience.
Long - term potentiation (LTP), a phenomenon in which brief repetitive activity causes a long lasting (many weeks) enhancement in the strength of synaptic transmission, is generally accepted to be a key cellular substrate for learning and memory.
They play a pivotal role in regulating synaptic transmission, modulating excitotoxicity responsible for much of the neuronal damage caused by hypoxic insult in the brain [37], and are expressed in retinal photoreceptors, horizontal cells, and bipolar cells as well as the amacrine and ganglion cells of the inner retina [38 — 41].
b1 - Integrins are required for hippocampal AMPA receptor - dependent synaptic transmission, synaptic plasticity, and working memory.
Review of the literature underlines a role for vesicular release of glutamate from astrocytes in synaptic transmission (Neuroscience 2009a).
These studies reveal for the first time specific functional connections between subsets of KCs and particular MBONs and establish the identity of synaptic microcircuits underlying transmission of homeostatic sleep signals in the MB.