Sentences with phrase «for systems biology approaches»

Specifically, the authors call for systems biology approaches (using large data sets and modeling to understand complex biological systems) to fill critical knowledge gaps in understanding how Mycobacterium tuberculosis (Mtb) infection causes disease.

Not exact matches

Over the past decade, the development of fast and affordable technologies for DNA sequencing and synthesis and a growing understanding of complex biological systems have opened the door to a new approach to biology.

In Europe, the Center for Research and Interdisciplinarity (CRI), for example, offers a 2 - year Interdisciplinary Approaches in Life Sciences master's program with a specific track in systems and synthetic biology.

The Transcriptomics Core Facility supports a systems biology approach in vaccine development focusing on the identification of transcriptomic correlates of vaccine immunogenicity and efficacy for a range of novel and licensed vaccines using PBMC or whole - blood and BAL fluid samples.

Extending cytokine / chemokine profiling platform (UNISI): Improvement of currently available services will be particularly focused on the optimisation of cytokine profiling for vaccine relevance using a systems biology approach.

The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo disease models to identify disease - associated genetic variants, disease - defining molecular signatures, and potential targets for therapeutic intervention.

Development of a gene expression assay in non-human primates: We will develop a novel sensitive assay for the characterisation of vaccination - related gene expression profiles in NHPs, using an approach that is fully harmonised with the systems biology platform.

Since biological systems challenge the available methods, and the necessary foundations in physics, computer science, and mathematics are often missing, the CellDevo track greatly benefits from the fundamental research in computer science, bio-image informatics, biophysics, and applied mathematics represented in the CompBio and BioPhysEng tracks and help to develop the methodological foundations for future biology in tight integration with life imaging and other experimental approaches.

His research interests belong to pushing frontiers of microscopy for cell biology, developing of new microscopical tools, systems and approaches.

An in vivo - vitro shuttle system for the study of P. cynomolgi liver stages12 is being exploited to better understand hypnozoite biology using molecular tools and genome - scale approaches, which rely on the availability of a complete and well annotated P. cynomolgi reference genome sequence.

Biomarkers (Rick Paules, Section Editor): This section will present a forum for innovative scientific studies that integrate genomic, proteomic and metabolomic approaches with studies of complex physiological regulatory processes to gain a systems biology insight into complex pathways and networks controlling homeostatic and pathophysiologic states.

Then for postdoctoral research I moved to Yale University, where I worked in a lab that looked at all kinds of different disease areas using the approaches of a field called chemical biology, which is using small molecules — chemicals — to probe biological systems in the hopes of developing compounds that could be new drugs.

New data and research approaches have created opportunities for researchers to study in detail many aspects of cancer biology, including how the normal biological programs of cell proliferation and death are altered during cancer and how the immune system responds to tumors.

This discovery approach greatly enhances the future potential of epistasis analysis for systems biology, and can complement genome - wide association studies as a means of formulating hypotheses for targeted experimental work.

She has also started her training with the Institute for Functional Medicine which teaches healthcare professionals to get to the root cause of lifestyle - driven disease through a patient - centered, systems biology approach.

Her ongoing clinical training through the Institute for Functional Medicine uses a systems biology approach when working with those who suffer from chronic and acute conditions to help them find their path to healing.

Dr. Brady will discuss autoimmune disease as a complex entity and «perfect storm» of biological and environmental factors and will present a systems - biology approach, utilizing a wider - lens perspective, as a suggested strategy and clinical algorithm for the clinician to consider in working through these complex clinical scenarios.

Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.

Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.

Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.

Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.

Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.