Sentences with phrase «for therapeutic discoveries»
Such an apothecary, Kasper added, is years away, but the results set the stage for therapeutic discoveries.
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There are a variety of reasons for this gap in understanding: The time gap between discovery research and the translation of that discovery into a therapeutic or a commercial product can take decades, and public and political attention spans are short; the natural human inclination is to pay more attention to things that don't work rather than things that do.
Of approximately 300 staff at the Center for Therapeutic Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and development.
«There is still a long way to go before diabetes patients might be able to benefit from these findings, but the discovery that delta cells have a high degree of plasticity points to a hitherto unsuspected option for therapeutic intervention.»
«Although this mutation only exists in a small percentage of cases, this discovery points to a potential therapeutic avenue for these patients.»
Unlike previously known causes, this new discovery points to a potential therapeutic approach for those few patients whose tumors harbor the mutation.
After a successful postdoc at the Ontario Cancer Institute, where he developed a proprietary platform for the discovery of novel cancer therapeutic agents, Bray was asked to join the former Amgen Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative biology group and act as liaison to Amgen Inc. in California.
The discovery of 6 - OH - dopa has therapeutic implications for more than just breast and ovarian cancer — the diseases most widely associated with BRCA mutations.
The discovery could have therapeutic ramifications for conditions including dementia, age - related memory loss or even post-traumatic stress disorder.
«This latest finding provides a concise and direct synthesis pathway that, due to the structure of the products delivered, will likely be quite valuable for the discovery and development of therapeutic agents,» says Micalizio, whose work focuses on the design of organic chemical reaction methods and strategies to improve medicine and human health.
Co-lead author, Doctor Mohammed Eslam, said this discovery holds great promise for the development of effective therapeutic treatments for liver disease.
GBM is a devastating disease that originates from glia or their precursors within the central nervous system, and the prognosis for GBM patients is unfortunately poor, but this discovery offers new therapeutic potential.
The discovery of a new therapeutic target for certain kinds of myeloproliferative disease is, without doubt, good news.
«This study opens an entirely new area of discovery for many aspects of cell biology and biomedical research — how cancer cells metastasize, for example — and provides many new therapeutic targets,» said senior author Jack Dixon, PhD, professor in the UC San Diego School of Medicine and associate vice chancellor of Scientific Affairs.
On the morning of Monday, October 3, the Nobel Committee announced that immunologist Ralph Steinman had won the Nobel Prize in Medicine for his work on immune cells and a discovery that led to the first therapeutic cancer vaccine.
«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author of the study.
Not only does this discovery improve our understanding of this communication system, it may also pave the way for new therapeutic strategies.
The discovery of this feedback mechanism also offers a number of targets for therapeutic intervention.
A $ 1.7 million drug discovery effort to identify molecular and genetic risk factors and new therapeutic targets for cognitive decline and Alzheimer's disease, based on data from the Religious Order Study and the Rush Memory and Aging Project.
Calling their compound a new therapeutic candidate for people with severe asthma and other chronic airway diseases, researchers say with additional research and development their discovery could lead to future clinical trials for asthma, Cystic Fibrosis and Chronic Obstructive Pulmonary Disease (COPD).
Their discovery may be harnessed for therapeutic control of body temperature in conditions where it's beneficial for temperature to be reduced, such as recovery after trauma.
«While we need to better understand how these abnormally regulated metabolites activate oncogenic proteins, our intriguing discovery suggests novel therapeutic targets for this disease,» says principal investigator and study leader Arnab Chakravarti, MD, chair and professor of Radiation Oncology and co-director of the Brain Tumor Program at the OSUCCC — James.
Research teams are also developing ways to innovate the early drug - discovery process, including pioneering methods to rapidly identify drug targets and test them on laboratory models and finding and testing new therapeutic possibilities for already FDA - approved drugs.
«To date, neither antiviral drugs nor vaccines are approved for clinical use against human parainfluenza virus, which reinforces the urgent need for new therapeutic discovery strategies.
Non-exclusive licenses are available for research and sale of products and services across multiple fields including: research tools, kits, reagents; discovery of novel targets for therapeutic intervention; cell lines for discovery and screening of novel drug candidates; GMP production of healthcare products; production of industrial materials such as enzymes, biofuels and chemicals; and synthetic biology.
ISIS PHARMACEUTICALS» FORWARD - LOOKING STATEMENT This press release includes forward - looking statements regarding the discovery, development and potential of drugs for severe and rare diseases, and the development, activity, therapeutic potential and safety of ISIS - SMNRx.
CRI presents the Coley Award to Jeffrey V. Ravetch for his work on Fc receptors, leading to fundamental discoveries critical to improving the design of therapeutic antibodies.
These forward - looking statements are based on management's current assumptions and expectations and involve risks, uncertainties and other important factors, specifically including those relating to Lexicon's ability to successfully conduct preclinical development of its drug candidates and advance such candidates into clinical development, achieve its operational objectives, obtain patent protection for its discoveries and establish strategic alliances, as well as those relating to manufacturing, the regulatory process, intellectual property rights, and the therapeutic or commercial value of its drug candidates, that may cause Lexicon's actual results to be materially different from any future results expressed or implied by such forward - looking statements.
The consolidation of these efforts in an independent initiative will allow faculty from the CMI to lead a focused investigation in small molecule drug discovery for multiple therapeutic applications.
These discoveries not only enhance our fundamental understanding of these conditions, but also point to potential therapeutic strategies for treating them.
While translational research has traditionally moved basic immunology knowledge forward into clinical application, varying clinical presentations of human immune - related disease processes, as well as variability in therapeutic outcomes, have provided opportunities for discovery of novel mechanistic hypotheses directly from patients.
«The discovery that aldose reductase regulates mucus production and goblet cell metaplasia makes inhibition of this enzyme an attractive therapeutic option to reduce mucus - related airway obstructive diseases — and for the first time gives us a real chance to alter the course of the underlying disease in asthma and COPD.»
«Nevertheless, this is a potentially exciting finding and it is possible that nivolumab, most likely in combination with other approaches such as therapeutic vaccines, may have a role in the eventual discovery of a cure for HIV.»
«The time frame for ESCs is now for drug discovery, soon for personalized medicine, and decades for therapeutic use.»
The publication of the discovery of leptin by (3) Zhang and Friedman et al (1994) created worldwide interest in this novel peptide as a tool for research and therapeutic discovery for obesity and its related disorders.
This discovery makes it possible to screen for the disease, and opens the door for potential new therapeutic approaches.
Consequently, the safest investment in the ESC field may be «something where you're an enabler of the technology» by providing the raw tools and ingredients for ESC research, says Steve Brozak, an analyst with WBB Securities in San Diego, Calif. «The time frame [for ESCs] is now for drug discovery, soon for personalized medicine, and decades for therapeutic use,» adds Bob Palay, chairman and CEO of Cellular Dynamics International (CDI), a biotech company working with ESCs in Madison, Wisc..
Objective: To provide data - driven and computational infrastructures and data - sharing platforms to support large - scale, system - level data integration and modeling, and enable predictive biology for pathogens and host - pathogen interactions for discovery research, clinical investigation, and therapeutic development for infectious diseases.
The patented discovery comes from Novocell's recognized research & development programs to commercialize pluripotent stem cells for broad research and therapeutic uses, in particular, for an innovative cell therapy for the treatment of diabetes.
We believe that leveraging human intuition through creation of a scientific game for drug discovery can not only provide a new avenue to discover therapeutic drugs for protein targets, but can also contribute to the development of new sophisticated algorithms to use in computer aided drug design.
Carmot is applying an innovative technology, Chemotype Evolution, to overcome the limitations of conventional discovery technologies and identify superior drug candidates for challenging therapeutic targets.
«Our discovery that RGS4 may play a role in the development of Parkinson's symptoms, helps us lay the groundwork for a new therapeutic strategy — independent of dopamine.»
Importantly, the molecular imaging models that are developed can be employed to accelerate the discovery of targets and drugs for therapeutic intervention, and biomarkers that could be used for early diagnosis.
This molecule brings a revolutionary technology platform for genetic engineering in vertebrates, including gene discovery in model species and for therapeutic transgene delivery for possible human applications.
Currently, Schreiber and colleagues in the Broad's Center for the Science of Therapeutics focus on integrating human biology with chemistry and chemical biology to discovery small molecules that modulate therapeutic targets at the heart of disease.
Carmot is applying a transformative technology, Chemotype Evolution, to overcome the limitations of conventional discovery technologies and to identify superior drug candidates for challenging therapeutic targets.
Our technology enables the identification of potential endoderm differentiation factors, leading to potential discovery of new drugs & agents for research, and, ultimately, therapeutic use.»
Langmuir 29 (35), 10973 - 10979 (2013) «Reduced limbic metabolism and fronto - cortical volume in rats vulnerable to alcohol addiction» A. Gozzi, F. Agosta, M. Massi, R. Ciccocioppo, and A. Bifone NeuroImage 69, 112 - 119 (2013) «Polymeric nanocarriers for controlled and enhanced delivery of therapeutic agents to the CNS» M. Gagliardi, G. Bardi and A. Bifone Theraputic Delivery, 3 (7), 875 — 887 (2012), doi: 10.4155 / TDE.12.55 «Neuromapping techniques in drug discovery: pharmacological MRI for the assessment of novel antipsychotics» A. Bifone and A. Gozzi Expert Opinions in Drug Discovery, 7 (11): 1071 - 82 (2012) «Neuroimaging evidence of altered fronto - cortical and striatal function after prolonged self - administration in the rat»
«We think this development will help other scientists better utilize open data, hopefully leading to the discovery of new therapeutic targets for disease,» says first author Andra Waagmeester, PhD, formerly a researcher at Maastricht University and now CEO of the start - up company Micelio.
Sorting breast cancer cells using a new reporter construct allows the interrogation of a highly pure population of cancer stem cells and may allow for the discovery of new therapeutic targets