Sentences with phrase «for therapeutic drug»

Adult Nurse Practitioner — Duties & Responsibilities Provide exceptional patient care and medical team support across multiple medical specialties Currently completing clinical and academic work toward a master of science in nursing Utilize strong background in biology, chemistry and mathematics Maintain working knowledge of current medical technology, procedures, and standards of care Proven ability to remain calm and levelheaded in high pressure situations Direct therapeutic, educational, and recreational activities for eight developmentally disabled adults Responsible for patient health, safety, and attainment of therapy goals Train and supervise medical lab personnel ensuring efficient and professional operations Offer guidance and support to junior lab technicians and medical technologists Perform a wide variety of daily testing utilizing machines such as AXSYM — Hitachi RA 1000 CX 7 Responsible for preventative maintenance on machines by running calibrations and controls Successfully complete monthly state proficiency tests for therapeutic drug, blood, and urine chemistries Prioritize stat specimens for immediate reporting Maintain direct contact with clients to resolve problems regarding appropriate tests and specimens Oversee confidential patient information, customer service, phones, and other administrative functions as needed Perform all duties in a positive, professional, and courteous manner

In a study to be published in the May 23 print issue of the journal Small (and currently available online [abstract]-RRB-, they demonstrate the ability to package drug - loaded «nanodisks» into vault nanoparticles, naturally occurring nanoscale capsules that have been engineered for therapeutic drug delivery.

In studies to understand the molecular basis for therapeutic drug action, he showed how tiotropium bromide (Spiriva), an inhaled drug for chronic obstructive pulmonary disease and for uncontrolled asthma, recognizes and blocks the muscarinic 3 (M3) receptor.

The identification of genes that are synthetically lethal in β - catenin - activated cancer cells would provide new targets for therapeutic drug design.

They could be used for therapeutic drug screening and to help teach researchers how to grow whole human organs.

We can then identify the right targets for therapeutic drugs,» he adds.

Piomelli et al. «The Endocannabinoid System as a Target for Therapeutic Drugs», Trends in Pharmacological Sciences (TiPS), 21: 218 - 224, 2000.

Not exact matches

Though hailed as «a new therapeutic principle» in 1990, it nonetheless took another eight years for the FDA to approve the first antisense drug, fomivirsen — for the treatment of AIDS - related retinitis caused by human cytomegalovirus.

There is significant preliminary research supporting the potential therapeutic value of CBD, and while it is not yet sufficient to support drug approval, it highlights the need for rigorous clinical research in this area.

Responsible opinion agrees that AA and the therapeutic communities are the most effective agencies around for enabling alcoholics and drug abusers to live their lives without chemical support.

In early March, USADA presented the Pacquiao camp with a contract that allowed the testing agency to grant a retroactive therapeutic use exemption (TUE) to either fighter in the event that the fighter tested positive for a prohibited drug.

Clenbuterol, a therapeutic drug first developed for people with breathing disorders such as asthma, is widely used by bodybuilders and athletes.

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

In addition, it has been restored for eight additional drug classes, including: anti-depressants, anti-retroviral, anti-rejection, seizure, epilepsy, endocrine, hematologic, and immunologic therapeutic.

And just this month, the federal Food and Drug Administration requested Endo Pharmaceuticals, an international pharmaceutical manufacturer, remove Opana ER — a semi-synthetic opioid painkiller — from the market after concluding the drug's potential for abuse outweighed its therapeutic vaDrug Administration requested Endo Pharmaceuticals, an international pharmaceutical manufacturer, remove Opana ER — a semi-synthetic opioid painkiller — from the market after concluding the drug's potential for abuse outweighed its therapeutic vadrug's potential for abuse outweighed its therapeutic value.

It also can keep out therapeutic drugs and, when defective, biomolecules that are needed for healthy brain development.

The finding, reported in tomorrow's issue of the Proceedings of the National Academy of Sciences, may help researchers narrow their search for a possible therapeutic drug against a condition that strikes one in 2000 male births.

«This could lead to a new therapeutic strategy for treating type 2 diabetes,» says Stanford, whose team believes that the drug could lead to fewer people with adult - onset diabetes becoming dependent on insulin injections.

Of approximately 300 staff at the Center for Therapeutic Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and development.

A pharmaceutical hit compound, like those discovered by Vogel and her co-authors, is a compound that is a promising candidate for chemical modification so it can eventually be delivered to patients as a therapeutic drug.

Once researchers understand the rules for how to get specific shapes with TZPs that also assemble into larger structures, they can design materials with desired functions — for example, a membrane for a battery, a catalyst for a fuel cell, or even a therapeutic drug.

For now, Rashid's group has a list of candidate therapeutic drugs that they'll test in their new liver disease models, something that may still prove useful to patients.

He is also the principal U.S. investigator for a randomized trial that began late last year in Germany and is now being conducted here to test the value of nicotine as a therapeutic drug.

«By administering chemotherapy within this «therapeutic window,» oncologists could apply a lower dose of chemotherapy drugs to patients, with the potential for an improved treatment outcome — all while minimizing drug toxicity to healthy organs,» He said.

If, however, you are more interested in research you could become a health outcomes researcher, collecting data on therapeutic interventions for drug companies, or there is the Scientists Training Programme offered by the NHS.

Instead of systematically testing the effects of known compounds — the pharmaceutical industry's basic model for more than a century — scientists can now investigate backward, combing through genomic data to find links between specific genotypes and diseases and then screening drug data to identify therapeutic candidates.

If these peptides are developed for therapeutic use, the researchers anticipate that they could be used either in stand - alone therapy or together with traditional antibiotics, which would make it more difficult for bacteria to evolve drug resistance.

Until now, EGFR inhibitors have only been effective at treating the 10 to 15 percent of non-small cell lung cancers that have a variant of EGFR, but the two - drug combo could potentially work for all non-small cell lung cancers, explained Dr. John Minna, Director of the Hamon Center for Therapeutic Oncology Research and Professor of Internal Medicine and Pharmacology.

«The number of protein functions that are currently targeted by drugs is incredibly small compared to the total number of protein interactions that could be targeted for therapeutic benefit,» says Geoffrey Wahl, a professor in Salk's Gene Expression Laboratory.

Much clinical research will be needed to determine whether those drugs are safe over a long period and have therapeutic benefits for people with Down syndrome,» said Sullivan.

UT Southwestern Medical Center cancer researchers have identified a protein critical to the spread of deadly cancer cells and determined how it works, paving the way for potential use in diagnosis and eventually possible therapeutic drugs to halt or slow the spread of cancer.

The authors suggest that these toxic metabolites could potentially be developed into therapeutic drugs for malaria and dengue.

Determining the detailed molecular mechanism that mediates the therapeutic actions of cannabidiol may suggest development strategies for new drugs aimed at GPR55, according to the researchers.

«Using approved therapies for one condition to treat another, or drug repurposing, offers new avenues to speed Parkinson's therapeutic development,» said Dr Brian Fiske, senior vice president of research programs at MJFF.

Structure - based drug design, in which the physical structure of a targeted protein is used to help identify compounds that will interact with it, has already been used to generate therapeutic agents for a number of infectious and metabolic diseases.

These new markers and tests could also be used to assist in treating drug dependence, in determining appropriate therapeutic levels of medical marijuana, and for monitoring women who want to stop using cannabinoids during pregnancy.

He is the co-founder and chief scientific officer of Novo Biosciences, a for - profit spinoff of the MDI Biological Laboratory whose goal is to realize the therapeutic potential of ZF143 and other drugs that speed tissue healing and stimulate the regeneration of lost and damaged body parts.

«And while the tumor model we're now studying doesn't present targets for new drugs, if we can discover the mechanism controlling that model, it may yield therapeutic drug targets.»

These drugs subsequently have low bioavailability (i.e., they are difficult for the body to take up), which limit their therapeutic efficacy and hence seldom leads to new pharmaceuticals.

This drug has been tested in clinical trials for the treatment of sepsis, and these findings suggest a therapeutic potential for the drug in the treatment of CCMs, although considerable research remains to be done.

«A significant amount of work remains in the development of teixobactin as a therapeutic antibiotic for human use — we are probably around six to ten years off a drug that doctors can prescribe to patients — but this is a real step in the right direction and now opens the door for improving our in vivo analogues.»

The researchers hope that a therapeutic drug will be particularly useful for combating outbreaks in unvaccinated hotspots.

A therapeutic screening center, headed by Lee Rubin at the Harvard Department of Stem Cell and Regenerative Biology, is dedicated to using induced pluripotent stem cells to find new drugs for genetic diseases.

Since small, early - stage cancers are the most responsive to drug treatments, screening is an important aspect of follow - up care for breast cancer patients, and early detection is critical in tailoring appropriate and effective therapeutic interventions.

The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.

Scientists say that suggests that by disrupting the recollection of a drug - associated memory — a person one abuses drugs with, a place that one uses drugs at, for example — a therapeutic may be able to break the connection between cues in the environment and the need for drugs.

«These results are particularly exciting because they suggest that drugs directed at fusion - circular RNAs could be a powerful strategy to pursue for future therapeutic development in cancer,» said Pandolfi.

This microRNA — miR -124-3p — is thus a potential therapeutic target for novel drug development, and it can serve as a putative biomarker for MDD pathogenesis.

«We have identified a novel therapeutic target for the treatment of severe influenza that is effective under conditions where known antiviral drugs fail to protect from death.»

The study, called «Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patients.