Sentences with phrase «for treating human diseases»

Data from a new study on how antibodies are developed in humans can be utilized to improve the development of therapeutic antibodies for treating human diseases.

Not exact matches

Salk Institute scientists say they have developed a superior way of cultivating human brain tissue, guiding research for treating neurological diseases such as Alzheimer's or Parkinson's.

Findings of the research, published April 22 in the journal Mucosal Immunology, reveal that a substance found in animal and human breast milk called epidermal growth factor, or EGF, blocks the activation of a protein responsible for unlocking the damaging immune cascade that culminates in NEC, a disease marked by the swift and irreversible death of intestinal tissue that remains one of the most - challenging - to - treat conditions.

Gene therapy delivered to a specific part of the brain reverses symptoms of depression in a mouse model of the disease — potentially laying the groundwork for a new approach to treating severe cases of human depression in which drugs are ineffective.

Building the knowledge base requires humans to teach computers key concepts from curated articles; with modest online training, anyone who reads English can scan research papers for key terms — names of genes, proteins, diseases, and drugs — and use online marking tools to document relationships between them (for example, drug X treats disease Y).

«If proven true, then combined use of metformin and rapamycin for treating aging and age - associated diseases in humans may be possible,» the researchers wrote in their conclusion.

According to Collins, «Beyond its importance for astronauts and future space explorers, this research also could lead to novel methods for preventing and treating human disease on Earth.

«Once we can build that sort of database for the human organism, it helps us much better understand disease, how to diagnose disease, how better to treat disease,» says Richard Wilson, the director of the Genome Sequencing Center at Washington University in St. Louis.

Additionally, work in a mouse model revealed similar cells, indicating that the progenitors are conserved from mouse to human, and therefore, they must be «important cells with promising potential for cell therapy in treating liver disease,» explained Dr. Gouon - Evans.

Research into how the brain processes time, sound and movement has implications for understanding how humans listen to music and speech, as well as for treating diseases like Parkinson's.

These developments have created countless opportunities for advancing our understanding and treating human disease.

Vaccines have treated infectious prions in mice, raising hopes of a cure for the deadly human version of «mad cow disease».

By pairing a receptor that targets neurons with a molecule that degrades the main component of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice brains and human brain tissue, offering a potential mechanism for treating the debilitating disease, as well as other conditions that involve either the brain or the eyes.

Since CGP3466B has already been tested in phase II clinical trials to (unsuccessfully) treat Parkinson's disease and ALS, it is known to be safe for humans, but the researchers caution that many more years of studies are needed to definitively show whether it is effective for preventing cocaine damage, first in mice, then in humans.

Understanding these redundancies, and how to bypass them, could be important for biomedical researchers wishing to manipulate gene activity to treat human diseases.

Mardinoglu says the team's network modeling approach, which relied on data from the Sweden - based Human Protein Atlas project and The Genotype - Tissue Expression (GTEx) project consortia, can be used in the identification of drug targets and eventually in the development of efficient strategies for treating a number of chronic liver diseases.

The team is now readying the vaccine for human trials and is designing related vaccines to treat other autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease.

And he says that in many areas there are strains of human H1N1 in circulation that are resistant to Tamiflu, the drug of choice for treating the disease in humans.

The experimental drug J147 is something of a modern elixir of life; it's been shown to treat Alzheimer's disease and reverse aging in mice and is almost ready for clinical trials in humans.

He added that the existence of episodic memory in lower animals has implications for research on human diseases that affect memory, including Alzheimer's, Parkinson's and Huntington's diseases, since the majority of research on the brain — and the drugs used to treat memory diseases and dementia — start out based on insights into how the brain works in rats.

Due to major advances in their immune potency DNA vaccines are being studied in human clinical trials for treating cancer and infectious diseases.

The team at UF's Powell Center for Rare Disease Research and Therapy conducted the first in - human study of gene therapy to treat respiratory dysfunction in patients with infantile onset Pompe.

If it does a similar job in humans, it could have huge potential for treating a wide - range of age - related diseases, say the researchers behind the latest work.

«Large animal models of human disease, like cats, are really helpful for determining what's going to happen in a child when you're treating them,» Vite said.

Given the rapid succession of generations in yeast, we can use it as a model organism — and study the mechanisms of aneuploidy in much greater detail to find out whether we can derive from it new approaches for diagnosing and treating human diseases.»

There are plans for human trials using stem cell therapy to treat inflammatory mouth disease as early as next year.

In addition, the findings may help guide emerging stem cell - directed technologies to generate normal kidney structures for studying and treating human kidney disease.

Woo Suk Hwang shot to fame in early 2004 for two papers in Science offering hope that cloned human stem cells could be used to treat diseases.

The result suggests that, although Hwang deceived the world about achieving the first human cloning, his group was first to succeed in performing human parthenogenesis, which may offer a way of creating cells that are genetically matched to a woman for transplantation back into her body to treat degenerative diseases.

Treating animals for a disease that can spread to humans is not unprecedented: The rabies vaccine routinely administered to pets in the developed world, for example, prevents the infection in animals, which in turn protects people.

Things may also be looking up for using iPS cells to treat human diseases.

If the bone is found to be safe and effective in humans, it could eventually provide a readily available and cheap material for treating periodontal disease.

Generated from human pluripotent stem cells (hPSCs), the miniature organs are being developed for their potential to study and treat liver disease.

This webinar will discuss the promise CRISPR / Cas9 has for rodent studies along with strategies for developing better models to understand and treat human disease.

The findings open up an avenue for treating Huntington's as well as other inherited neurodegenerative diseases, although more testing of safety and long - term effects is needed, says senior author Xiao - Jiang Li, MD, PhD, distinguished professor of human genetics at Emory University School of Medicine.

Mammoth hemoglobin, for example, may reveal information about mammalian blood useful to treating human diseases, and potentially the future of human space exploration (such as surviving cold environments); but the mutations that create mammoth hemoglobin need to be brought back to life for such discoveries to happen.

According to Penetar, puerarin was selected over other kudzu root components because its safety and efficacy have already been established in humans, particularly in China where it is approved for intravenous injection to treat coronary heart disease, myocardial infarction and angina.

Touted widely for its potential, CRISPR / Cas9 gene editing has not been used to treat any neurodegenerative disease in humans.

«In particular, his approach can be thought of as a very advanced biological therapy for the treatment of breast cancer; one that uses viruses, which are better recognized to cause disease, to treat human breast cancers.»

The stem cell research community hopes that as more is understood about STAP cells, they will join embryonic stem and iPS cells as another reprogramming tool for use in their collective quest to understand and treat human disease.

The Sanford Consortium for Regenerative Medicine facility is intended to house biologists, chemists, technologists, bioengineers, computer scientists and clinicians in open laboratories and is designed to facilitate and encourage collaboration among them as required to translate the basic understanding of stem cell science into tools useful to diagnose and treat human disease.

DUBs: The ubiquitin proteasome system represents an exciting and underexplored target class for treating many human diseases.

LA JOLLA — The experimental drug J147 is something of a modern elixir of life; it's been shown to treat Alzheimer's disease and reverse aging in mice and is almost ready for clinical trials in humans.

ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

These cells can potentially turn into many different types of cells, and offer staggering potential for treating a huge range of human diseases.

Recently, Gladstone Senior Investigator Yadong Huang, MD, PhD, found that a drug used for years to treat heart failure also seems to reverse signs of Alzheimer's disease in both human and mouse brains.

«For a nice two decades scientists have dreamt about using human embryonic stem cells to treat diseases... that day has finally come... scientists have used human embryonic stem cells to successfully treat patients suffering from severe vision loss»

The Human Cell Atlas (HCA) Consortium has released a blueprint for the international initiative's efforts to create a comprehensive reference map of all human cells, a project that will form the basis for a deeper understanding of human health and for diagnosing, monitoring, and treating disHuman Cell Atlas (HCA) Consortium has released a blueprint for the international initiative's efforts to create a comprehensive reference map of all human cells, a project that will form the basis for a deeper understanding of human health and for diagnosing, monitoring, and treating dishuman cells, a project that will form the basis for a deeper understanding of human health and for diagnosing, monitoring, and treating dishuman health and for diagnosing, monitoring, and treating disease.

The Human Cell Atlas (HCA) is an international collaborative consortium, which aims to create comprehensive reference maps of all human cells — the fundamental units of life — as a basis for both understanding human health and diagnosing, monitoring, and treating disHuman Cell Atlas (HCA) is an international collaborative consortium, which aims to create comprehensive reference maps of all human cells — the fundamental units of life — as a basis for both understanding human health and diagnosing, monitoring, and treating dishuman cells — the fundamental units of life — as a basis for both understanding human health and diagnosing, monitoring, and treating dishuman health and diagnosing, monitoring, and treating disease.

In addition, our studies provide a specific population of human astrocytes that appears to be particularly suitable for further development towards clinical application in treating the traumatically injured or diseased human central nervous system.