Sentences with phrase «for tumorigenic»

Not exact matches

The pathologist of the Department of Pathology at the University Hospital of Bellvitge August Vidal explained that «this tumorigenic transformation depends on Dicer protein that could serve as a marker for the presence of tumor cells, or as a therapeutic target.»

The prevailing theory of cancer progression — that it's driven by the accumulation of genetic mutations that increase tumorigenic «fitness» — holds true for the early stages of cancer progression, but metastases seem to find new ways to increase their fitness, McDonald said.

For example, low grade inflammation in the tumour microenvironment can attract detrimental regulatory cells and neutrophils which can inhibit tumour immunity and promote tumorigenic factors.14

Although we agree that greater investments are needed in the clinical development of these therapies, we disagree with the authors» suggestion that, relative to embryonic stem cells, adult stem cells provide a superior vehicle for cell - based therapies because they lack tumorigenic activity, can be prepared by methods approved by the Food and Drug Administration (FDA), and have been free of ethical controversy.

FDA's position on assessment of tumorigenic potential of cell products for regenerative medicine

Finally, the study suggests new tumorigenic and cellular functions of BAP1 and shows for the first time the interest of studying the proteome as readout of BAP1 inactivation.

The Transcription Factor ZFX Is Required for Maintaining the Tumorigenic Potential of Glioblastoma Stem Cells.