Not exact matches
This image highlights the key finding: that PTEN directly «destroys» PI (3,4) P2 and that PI (3,4) P2 is a marker
for tumour growth and
progression.
«Naked mole rats have an additional barrier in the way of
tumour progression,» says Seluanov, who presented the results at the Strategies
for Engineered Negligible Senescence meeting in Cambridge, UK, last week.
«Our results indicate it is a promising agent
for clinical trials, and a as an add - on to more conventional therapies, to prevent
tumour recurrence, further disease
progression and metastasis.»
«The new knowledge we have gained facilitates the design of prophylactic and therapeutic measures
for delaying
tumour progression and extending cancer - free periods in RDEB,» says Venugopal Rao Mittapalli, the first author of the study.
For patients with cervical cancer that has recurred after treatment or has spread elsewhere in the body, adding the experimental drug cediranib to standard chemotherapy improves
tumour shrinkage and adds a modest improvement in
progression - free survival, researchers report at the ESMO 2014 Congress in Madrid.
«Similarly 71 drugs approved by the FDA from 2002 to 2014
for solid
tumours have resulted in median gains in
progression - free and overall survival of only 2.5 and 2.1 months, respectively,» he says adding, «Also, only 42 per cent met the American Society of Clinical Oncology Cancer Research Committee's criteria
for meaningful results
for patients.»
Because the
tumour is located in an area of the brain which makes surgery risky, Alix is on a watchful waiting program, with brain scans every six months to monitor
for progression.