In all, the researchers were able to position more than 1000 markers on the chromosome that will help them and others hunt
for useful genes.
Not exact matches
Keith Fargo, the Alzheimer's Association director of scientific programs and outreach, told Business Insider in 2017 that the Alzheimer's report, which would tell me whether I had a mutation on my APOE
gene, was more
useful in the context of research than it was
for predicting who might get the disease.
On the contrary, he finds it
useful to ponder an array of reductionist attempts to explain the existence of religion, from that which seeks to pinpoint the area of the human brain or the specific
genes connected to religiosity to that which sees religion as a malfunction of the human mind or a vestigial remnant from a primitive stage of human development suitable only
for whimpering, immature dullards (a point of view championed by the new atheists).
Beyond this, the unique power of GM lies in its ability to incorporate novel
genes with
useful traits
for rice, including
genes from plants and organisms unrelated to rice, into new rice varieties that can not be achieved using other breeding methods.
It's
useful to keep in mind that no one is born with a
gene for automatically knowing how to care
for an infant!
Juan Carlos Izpisúa Belmonte of the Salk Institute in La Jolla, California, knew that stem cells are more
useful for gene therapy than ordinary cells, because they produce multiple daughter cells with the modified
genes.
«CRISPR - on is a tool that will be very
useful for studying many biological processes, particularly
for studying
gene functions and
gene networks,» says Whitehead Founding Member Rudolf Jaenisch.
But when the researchers compared the genomes of opossums and humans, they found a surprising number of similar immune - related
genes, meaning it's
useful for just the opposite of the expected reason: The gray short - tailed opossum is a nice model
for immunology research.
And a dog genome sequence has made the animals an even more
useful model by quickening the search
for disease - causing
genes.
These results illustrate a
useful approach
for studying the effect of
gene expression on cardiac contractility.
While the baby was breastfeeding, the bacteria in his stomach contained numerous
genes useful for breaking down milk sugars.
For the dozens of labs at work on the problem, coming up with
useful genes, known as transgenes, is not the hard part — it's how to transfer enough copies of the transgenes into free - ranging populations.
The work, published in tomorrow's issue of Science, * holds out hope that
gene therapy will be
useful for limiting the severity of Parkinson's, a progressive disease that afflicts about 500,000 people in the United States alone.
Infidelity may sound like a bad thing to humans, but
for birds, Botero says, seeking out superior
genes could be a
useful strategy
for surviving climate change.
The results showed that AAV was in fact
useful for gene therapy; it just had to be applied the right way.
«While they're
useful for studying
gene function in an animal, they also have their own inherent interest,» Melton says.
Although AdV proved too destructive
for regular
gene therapy,
for instance, it turns out to be supremely
useful in treating cancer, where you want to rouse the immune system.
«These findings illustrate how resurrection plants manipulate sugar metabolism to promote desiccation tolerance and may provide candidate
genes that are potentially
useful for the development of stress tolerant crops.»
«Soybean genotypes carrying Rpp1b, Rpp2, Rpp3, and Rpp5a resistance
genes, and cultivars Hyuuga and UG5 (carrying more than one resistance
gene), were observed to be resistant against most of the African rust strains, and therefore may be
useful for soybean - breeding programs in Africa and elsewhere,» Hartman says.
For example, many of the
genes in the new networks are related to cancer, suggesting that certain cancer treatments that target these
genes might also be
useful to treat ASD.
«Nevertheless, this
gene will be
useful in combination with other STB resistance
genes, and our study provides tools
for rapid lab - based tracing of Stb6 in wheat breeding lines,» says Kanyuka.
This test may be particularly
useful for patients with high grade serous ovarian cancer because the mutated cancer
gene TP53 is found in more than 99 per cent of patients with this form of the disease.
Molecular geneticist Lisa Baumbach of the University of Miami says the technique should be
useful in screening
for inherited forms of breast cancer,
for which researchers must use many probes to distinguish among multiple mutations in a
gene.
Because the precise activation of Hox
genes is essential
for a cell's fate, «the research should prove extremely
useful in developing novel embryonic stem cell - based therapies, Mazzoni adds.
The new AAV vectors can also deliver
genes that code
for colorful fluorescent proteins; such proteins are
useful in identifying and labeling cells.
Given how
useful any insights into
gene function are
for understanding the genetic basis of disease, the data are «priceless,» says Kári Stephánsson, a geneticist at deCODE in Reykjavík.
It is only the handful of
genes that differ, such as those defining blood group, which are
useful for making maps.
The
gene may be
useful for diagnosing the condition or projecting the risk of disease in people who are healthy, but there isn't a lot of profit in testing people.
Similarly, carriers in the Jackson study of one copy of the
genes that cause sickle - cell disease — a
useful trait against malaria in Africa — appear to be more at risk
for kidney disease.
It is particularly
useful when clinicians want to identify an illness or
gene mutation involving a single patient or the patient and two or three other family members, which is the most common clinical situation
for undiagnosed diseases.
Further work is required to consider if certain
gene pathways may provide a base
for useful interventions.»
Those
genes could be at the root of inherited sleep disorders, Blackshaw says, and the proteins they make could prove
useful as starting points
for the development of new drugs to treat insomnia and even jet lag.
These include Cenix Bioscience, which has developed a new lab technique to identify the
genes that are involved in cell division, predicted to be very
useful for finding potential new targets
for anticancer drugs.
Some proteins recycled from jumping
gene parts have also proved extremely
useful, especially
for the immune system.
Tomatoes are already an ideal model species
for plant research, but scientists at the Boyce Thompson Institute (BTI) just made them even more
useful by cutting the time required to modify their
genes by six weeks.
«This technique will be
useful for other studies interested in characterising the link between
gene expression and physical, external traits.»
The strategy of single - cut editing may be
useful for treating other single -
gene diseases, Dr. Olson said.
But they could also transplant groups of interacting
genes, creating more humanlike yeast that would be
useful for studying new drugs or molecular circuits that go awry in diseases.
In a report today, that panel endorsed Obama's broad proposal, finding that a 1 - million - person study will be
useful for finding
genes and biomarkers that influence disease risk and response to drugs.
«We chose these
genes because they have proven
useful for classification of related groups of bats,» said Velazco.
Without knowing which
gene variants were contributing
useful properties, people simply selected the best plants
for continued cultivation, in this case choosing plants that had large backpacks.
The cellulose
gene may eventually be
useful in developing new, high - fiber products, but don't look
for tougher clothes or stronger two - by - fours anytime soon.
It is expected that the new technique will be applied to
gene therapy in the future in addition to providing a powerful tool
for breeding
useful organisms and conducting disease and drug - discovery research.
So far, the CRISPR system has mostly been exploited as a
gene editing tool, but it may also prove
useful for medical testing.
The new finding suggests that this may not be a
useful a strategy in the future, because if the resistant rats hold their own or become dominant, the
gene for resistance will not disappear.
The authors conclude that there are many applications
for which using the I - score would be
useful,
for example in formulating predictions about diseases with high dimensional data, such as
gene datasets, in the social sciences
for text prediction or financial markets predictions; in terrorism, civil war, elections and financial markets.
Adeno - associated viruses (AAVs) make fantastic
gene delivery vehicles
for episomal
gene expression and are particularly
useful for gene delivery to the nervous system.
These muscle progenies will be very
useful to design
gene repair strategies
for DMD patients.
In addition, we have generated a high - quality RNA - Seq
gene annotation pipeline that is now routinely used in Ensembl annotation and is proving particularly
useful for species with very little protein or cDNA evidence.
Although CRISPR is incredibly
useful for generating mutations by NHEJ and generating small mutations with HDR, when it comes to larger scale genome editing, such as replacement of a mouse
gene with its human ortholog (greater than 5 kb), it remains to be seen whether CRISPR is as robust as conventional
gene targeting.