Sentences with phrase «for vascular endothelial growth factor»

In 1989, the gene for vascular endothelial growth factor (VEGF) is identified, leading to the development of anti-angiogenesis treatments including bevacizumab (Avastin) for cancer.

His study highlighted a role for vascular endothelial growth factor (VEGF) in N - methyl - D - aspartate (NMDA) receptor trafficking via the activation of long - term potentiation signaling pathways at the post-synaptic sites (De Rossi et al, 2016).

So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem cells to biodegradable nanoparticles carrying the human gene for vascular endothelial growth factor (VEGF), which attracts blood vessels to injury sites.

Not exact matches

A critical discovery in this research was finding that the novel progenitor has a receptor protein on its cell surface called KDR, or vascular endothelial growth factor receptor 2, which until now, was thought to be restricted to endothelial cells that form vessels, the progenitors for endothelial cells and the progenitors blood cells.

Pancreatic cyst fluid is tested for a biomarker, a specific isoform of vascular endothelial growth factor A, or VEGF - A.

They focused towards this end on the vascular growth factor Angiopoietin - 2, which is produced by endothelial cells and does not just control angiogenesis, but acts as a key responsiveness factor for endothelial cells.

High serum vascular endothelial growth factor level is an adverse prognostic factor for high - risk diffuse large B - cell lymphoma patients treated with dose - dense chemoimmunotherapy.

During his career, Dr. Aiello has received numerous awards, including sharing the 2014 Antonio Champalimaud Vision Award with Dr. George L. King at Joslin for their contributions toward the discovery of treatments inhibiting vascular endothelial growth factor (VEGF) for diabetic eye disease.

Vascular endothelial growth factor signaling is necessary for expansion of medullary microvessels during postnatal kidney development.

Bevacizumab (Avastin ®), which targets vascular endothelial growth factor (VEGF), is FDA - approved for the treatment of ovarian cancer.

Phase II study of cediranib (AZD 2171), an inhibitor of the vascular endothelial growth factor receptor, for second - line therapy of small cell lung cancer (NCI # 7097).

For the analysis of mRNA levels for asparagine synthetase (ASNS), CHOP (CCAAT / enhancer - binding protein homologous protein), vascular endothelial growth factor (VEGF), glucose transporter 1 (Slc2a1) and monocarboxylate transporter 4 (Slc16a3), RT - PCR as well as qPCR were usFor the analysis of mRNA levels for asparagine synthetase (ASNS), CHOP (CCAAT / enhancer - binding protein homologous protein), vascular endothelial growth factor (VEGF), glucose transporter 1 (Slc2a1) and monocarboxylate transporter 4 (Slc16a3), RT - PCR as well as qPCR were usfor asparagine synthetase (ASNS), CHOP (CCAAT / enhancer - binding protein homologous protein), vascular endothelial growth factor (VEGF), glucose transporter 1 (Slc2a1) and monocarboxylate transporter 4 (Slc16a3), RT - PCR as well as qPCR were used.

From these cell based and clinical studies, we have developed important mechanistic ideas such as activation of protein kinase C, the role of vascular endothelial growth factor (VEGF) and selective insulin resistance as some of the basic mechanisms for the pathogenesis of diabetic microvascular and cardiovascular diseases which are now widely studied by multiple laboratories.

In 1996, for instance, Semenza demonstrated that HIF - 1 activates the gene for a key participant in blood - vessel formation, vascular endothelial growth factor (VEGF).

One class of drugs, called vascular endothelial growth factor inhibitors, for example, is designed to thwart the growth of abnormal blood vessels in the eye.

At the same time, the protein Vascular Endothelial Growth Factor (VEGF) stimulates blood supply for the damaged tissue, Fibroblast Growth Factor - 2 (FGF - 2) stimulates the damaged cells to grow and reproduce themselves, Transforming Growth Factor - beta (TGF - beta) stimulates cartilage to grow, and Stem Cell Factor (SCF) stimulates your native inactive stem cells to become activated and assist in the repair of the damaged tissue.