Not exact matches
Unlike the previous studies that focused on certain species or a particular RNA virus, Skalka went broad: She and her colleagues surveyed every
vertebrate genome available, 48 in all, and looked
for hints of 5666 RNA viral sequences from 38 known families and nine genera that were unclassified.
Before the consortium came together, he had participated in sequencing the
genomes of two vocal learners, a songbird and a parrot, but he knew he couldn't do all of the additional sequencing and analysis work that would be required to identify genes related to vocal learning — not by himself, at least — so he teamed up with
Genome 10K, a project aiming to collect
genomes for 10,000
vertebrate species.
Hughes's winning research proposed using microarray techniques to compare the
genomes of a variety of
vertebrate animals to test
for common regulatory elements that determine gene expression.
For most
vertebrates it's not immediately apparent why
genome deletions and add - ons typically go hand - in - hand.
While that is close to true
for coelacanths, other famous «living fossils,» which have the slowest molecular evolutionary rate among
vertebrates, the Lingula
genome has been evolving rapidly, despite the lack of changes in appearance.
In 2009, he and two others started the
Genome 10K project, a call
for the sequencing of 10,000
vertebrates.
«This is the first time the complete genetic code — the
genome — of any
vertebrate species from Panama has been sequenced and analyzed,» said Oris Sanjur, co-author and Associate Director
for Science Administration at STRI.
«Our study reveals a spectrum of methods that nature uses to allow organisms to adapt to different environments,» said senior author Kerstin Lindblad - Toh, Scientific Director of
Vertebrate Genome Biology at the Broad Institute: «These mechanisms are likely to be also at work in humans and other
vertebrates, and by focusing on the remarkably diverse cichlid fishes, we were able to study this process on a broad scale
for the first time.»
The
Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) has been designed to be a community resource for browsing manual annotation of finished sequences from a variety of vertebrat
Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) has been designed to be a community resource
for browsing manual annotation of finished sequences from a variety of
vertebratevertebrate genomes.
The
Vertebrate Genome Annotation (Vega) database is a community resource for browsing manual annotation from a variety of vertebrate genomes of finished sequence (http://vega.sang
Vertebrate Genome Annotation (Vega) database is a community resource
for browsing manual annotation from a variety of
vertebrate genomes of finished sequence (http://vega.sang
vertebrate genomes of finished sequence (http://vega.sanger.ac.uk).
Among
vertebrates, the fish model displays easy high density breeding (short generation time), favourable biological peculiarities (accessibility and transparency of the eggs,
genome sequenced
for both species used on the platform), original technological approaches (confocal and two - photon microscopy), as well as a wide accessibility to fully transparent larvae usable up to 5 days after fertilization.
The phylogenetic position of the cephalochordate amphioxus, together with its relatively simple and evolutionarily conserved morphology and
genome structure, has led to its use as a model
for studies of animal evolution, with a special focus on the origin of deuterostomes, chordates, and
vertebrates.
«Our study reveals a spectrum of methods that nature uses to allow organisms to adapt to different environments,» said co-senior author Kerstin Lindblad - Toh, Co-Director of SciLifeLab, scientific director of
vertebrate genome biology at the Broad Institute and professor in comparative genomics at Uppsala University «These mechanisms are likely also at work in humans and other
vertebrates, and by focusing on the remarkably diverse cichlid fishes, we were able to study this process on a broad scale
for the first time.»
The list of organisms that have been totally or partially sequenced continues to grow: As of April 2013, whole
genome sequences have been generated
for 112
vertebrates, along with 455 non-
vertebrates and nearly 9,000, mostly harmful, bacteria.