Phytoestrogens are plant - based compounds that act in a manner similar to the natural
form of estrogen found in the body.
While not true hormones, isoflavones closely resemble estradiol (E2), 16 the most potent of the three
forms of estrogen found in the human body17 and the form of estrogen that has been implicated in thyroid cancer.18 - 20 Soy isoflavones cause significant endocrine disruption both directly by binding with estrogen receptors, and indirectly by interfering with the body's production of estrogen, testosterone and other hormones.
Not exact matches
They
found that women with higher concentrations
of BPA had lower peaks
of estradiol, a
form of estrogen important in the development
of eggs in the ovaries.
A compound called 10β,17β - dihydroxyestra 1,4 dien -3-one (DHED), they
found, relies on an enzyme in the brain to be converted from its «prodrug»
form into the active
form of estrogen; other organs in the body use different starting blocks to generate the hormone.
When the investigators analyzed the genes
of MECs infected with EBV, they
found genetic characteristics associated with high - grade,
estrogen - receptor - negative breast cancer (an aggressive
form of the disease).
Dietary
estrogens in the
form of soy foods were
found to have the potential to disrupt the endocrine system with the effects in women similar to taking the breast cancer drug tamoxifen (Proceedings
of the Society for Experimental Biology and Medicine 1995 Jan; 208 (1): 51 - 9).
A tissue culture study
of human breast - cancer cells
found that epigallocatechin gallate, or EGCG, an active compound in green tea, protects against some
forms of breast cancer by regulating
estrogen receptors on breast cells and inhibiting growth and reproduction
of estrogen - dependant breast - cancer cells.