Sentences with phrase «form of human malaria»

I started my PhD in the Cell Surface Signalling Group in 2013 and have since been investigating how Plasmodium falciparum parasites, the causative agent of the most severe form of human malaria, interact with their human host.

Both manuscripts detail the role of the same AP2 - G transcriptional regulator with remarkably similar findings — despite the different groups» having worked with two highly diverged malaria parasites: Plasmodium falciparum, which causes the most severe form of human malaria and Plasmodium berghei, a commonly used model parasite infecting rodents.

Not exact matches

The most serious forms of the disease are caused by Plasmodium falciparum and Plasmodium vivax, but other related species (Plasmodium ovale and Plasmodium malariae) can also infect humans.

In 1967, Ruth found that irradiating malaria - infected mosquitoes with X-rays weakened sporozoites, the form of the malaria parasite that is transmitted to humans during mosquito bites.

Surprisingly, the major blood stage form of the parasite that causes the terrible cycles of intense fevers associated with malaria in humans can not be transmitted to mosquitos.

Two teams have independently discovered that a single regulatory protein acts as the master genetic switch that triggers the development of male and female sexual forms (termed gametocytes) of the malaria parasite, solving a long - standing mystery in parasite biology with important implications for human health.

Researchers have discovered that protection from the most severe form of malaria is linked with natural variation in human red blood cell genes.

To test their method, the researchers looked at functional predictions of a protozoan parasite known to cause the most severe form of malaria in humans — Plasmodium falciparum.

Others speculated that, like the malaria drug chloroquine, artemisinin frustrates the removal of haem, a toxic byproduct formed during the parasite's consumption of human hemoglobin.

A human vaccine against malaria has faltered in the face of the sophisticated life cycle of Plasmodium falciparum, the one - celled parasite responsible for the most severe form of the disease.

A new study reveals a new hypothesis on the evolution of hundreds of species of malaria — including the form that is deadly to humans.