Sentences with phrase «form tangled»

Different mobile devices, media platforms, and industries require different content formats and standards, and this can form a tangled web of specifications.

As beta amyloid proteins intertwine, they form tangled clumps that block the passage of signals from cell to cell.

Sup35 is a prion — a type of protein that can form tangled clumps known as amyloids.

The shock fronts form tangled, knotted clumps of nebulosity and are collectively known as Herbig - Haro (HH) objects.

The proteins might instead form tangles that act like hair blocking a drain, Ellis - Behnke suggests.

In a brain ravaged by Alzheimer's, microtubules, which are crucial to cell communication, disintegrate as tau proteins (blue) form tangles and amyloid proteins (green) form plaques.

«So our idea was to chop the protein back to their normal size so they wouldn't form these tangles.»

In its rush to grow, cancer forms tangles of blood vessels, but those slapdash vessels are leaky.

If the proteins can not form correctly and be transported easily, they form tangles that cause a cascade of problems.»

Yorkies» hair usually forms tangles because it is not brushed or is brushed incorrectly.

While this is a natural process, without regular grooming, this hair will become mixed with grease, dirt and debris, forming tangles and eventually a dirty, matted layer.

Cats become greasy and shed their hair, which then mixes with dirt and debris, forming a tangled layer.

Even more so than bulrush, this species forms tangled, soil - stabilizing matrices of roots, shooting up and spreading much like a runaway mint plant in your garden (though it's always welcome!).

Krantz's work springs from an engagement with the meaning of this hopeful gesture and becomes one itself as stroke upon stroke of bright color are laid down forming her tangled piles.

Not exact matches

Unlike the wet stuff in the ocean that gets tangled in your legs and momentarily makes you think that an octopus has trapped your leg, this stuff comes in dried flake form, somewhat similar in texture to nutritional yeast or dried herbs.

With whichever footballers have fallen out of the tangled machine that is development, coaching, and competition; have managed to find decent form and avoid injury; were born this side of a border and not that.

On - form Helen Wyman had a problem on one of Namur's numerous drop - offs on lap one, tangling in the barriers and losing precious seconds.

Commonly they are made of mesh, and after your little one poking and prodding at it enough, holes can form and your little one can ultimately get trapped and tangled within it.

Although amyloid clogs the brain early on, memory loss tracks much better with a different protein, tau, which forms so - called «tangles» within nerve cells.

Once tangles form, they spread like wildfire and keep spreading.

This can lead to errors; newly emerging transcripts will get tangled up, forming loops that are lethal to the cell.

These plaques, which are believed to cause the dementia associated with the disease, are made up of tangles of amyloid beta (Aβ), a protein that is found in soluble form in healthy individuals.

Several factors have been implicated in Alzheimer's, including the build - up of an abnormal protein called beta amyloid, fibrous tangles in the brain involving abnormal forms of a protein called tau, and — most recently — an association between the disease and a gene called ApoE.

«When tau is abnormally modified, it accumulates within neurons forming sticky tangles, and the when the cell dies, it and the amyloid beta spill out into the brain.

Similar to how water in a bathtub forms a whirlpool as it goes down a drain, the gas and magnetic fields that feed a supermassive black hole swirl to form a rotating disk — a tangled spaghetti of magnetic field lines mixed into a broth of hot gas.

Not only did the normal mice develop plaques, but also a pathology similar to «tangles» — twisted protein strands that form inside brain cells, disrupting their function and eventually killing them from the inside - out.

In several diseases of the brain, long fibres of protein form, and eventually become tangled to form dense bodies known as «plaque» or «aggregates.»

A definitive diagnosis of Alzheimer's includes dementia and two distortions in the brain: amyloid plaques, sticky accumulations of misfolded pieces of protein known as amyloid beta peptides; and neurofibrillary tangles, formed when proteins called tau clump into long filaments that twist around each other like ribbons.

Neurons responsible for producing key neurotransmitters — among them acetylcholine, noradrenaline and 5 - hydroxytryptophan — begin to fail, traces of the plaques and tangles that infest the brains of Alzheimer's patients begin to form, and the organ as a whole shrinks.

Together, these plaques and neurofibrillary tangles form the pathological hallmarks of the disease.

Also, he says that if the treatment doesn't block the tau protein tangles that accumulate in neurons of Alzheimer's patients, the disease might advance even if cells survive and form connections to others.

The disease is largely attributed to an abnormal buildup of proteins, which can form amyloid beta plaques and tangles in the brain that trigger inflammation and result in the loss of brain connections called synapses, the effect most strongly associated with cognitive decline.

Amyloid - β clumps into whitish plaques, tau forms ribbons called tangles and α - synuclein creates fibrous deposits called inclusions.

But in Alzheimer's, tau clumps together, which is thought to harm the brain, and causes twisted tangles to form.

It is this sensitive, tangled transaction that forms the focus of Bioinformation: how can things that are so intimate, personal and powerful be ethically extracted and repurposed on an enormous scale?

«Tau aggregates to form the hall - mark tangles of Alzheimer's disease and serves as the best marker of disease progression.

It is interesting to contemplate a tangled bank coded with many species of plants of many kinds, with birds singing on the trees, with various insects flitting about and with worms crawling through the damp earth and to reflect that these elaborately constructed forms, so different from each other and dependent upon each other in sole complex of manner, have all been produced by laws acting around us.

Glenner's research eventually morphed into the «amyloid cascade hypothesis,» which says that the formation of amyloid - beta plaques leads to tangled forms of another protein, tau, and ultimately to inflammation in the brain.

The next step, he says, will be to use his team's three - dimensional «Alzheimer's in a dish» model to see whether microbes can induce amyloid - beta plaques to form in human brain tissue, and then whether those plaques lead to tau tangles and inflammation.

In mouse models of the disease, tau tangles didn't form after the plaques appeared.

AS MANY DIFFERENT, AND sometimes conflicting, strands of research continue to probe how and why plaques and tangles form in the brain, the ultimate goal is to find a way to keep that from happening.

Alzheimer's disease, the most common form of dementia, is characterized by the accumulation of plaques (composed of amyloid - beta protein) and fibrous tangles (composed of abnormal tau) in brain cells called neurons.

Pre-assembled tau filaments phosphorylated by GSK - 3b form large tangle - like structures.

Everyone knows that long bits of yarn, or charging cables and the like, tend to get quickly tangled and form nasty knots.

During the subtraction reaction, tangled hybrids form randomly between these long tails of unrelated DNA molecules.

Surprisingly, the same yeast chaperone also interacts with beta - amyloids, fibrous peptides that forms the destructive tangles which are believed to cause Alzheimer's disease.

Except for the fact that they can both change shape and form large protein tangles, scientists hadn't detected any significant similarities between them.

Now they can form abnormal tangles, which can help kill brain cells.

The neurofibrillary tangles found in Alzheimer's disease consist primarily of a protein called tau, which forms part of a structure called a microtubule.

They may form thread - like tangles that jam up the transport system.