Sentences with phrase «formation of tumors through»

Carcinogenesis is a multistep process, and oxidative damage is linked to formation of tumors through several mechanisms (9, 10).

Not exact matches

Loss of this function causes tumor formation through uncontrolled stimulation of AKT, an enzyme that stimulates cell proliferation and survival and is often hyperactive in human tumors.

We also found that the EphB4 receptor expressed on the surface of breast cancer cells can promote tumor xenograft growth by enhancing blood vessel formation through interactions with its preferred ligand, ephrin - B2, present in tumor endothelial cells.